Huminsulin 40/60 40 IU Injection 10 ML

Lupin Ltd

Pack of 10 ML

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Old MRP ₹174

MRP ~~₹163.12~~

₹130.5

₹16.31/ML

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Prescription required for this medicine

Store in refrigerator or (2^o - 8^o C) Do Not Freeze

Composition

Human Premix Insulin (40 Iu)

Huminsulin 40/60 40 IU Injection 10 ML is a premixed human insulin preparation used to maintain stable blood sugar levels in patients with diabetes mellitus. It contains a combination of 30% soluble (short-acting) insulin and 70% isophane (intermediate-acting) insulin. This formula mimics the body's natural insulin release pattern, providing a quick effect to cover post-meal sugar spikes and a steady effect to manage glucose levels between meals.

This injection is used for both Type 1 and Type 2 diabetes to provide day-long glucose control. It is typically administered subcutaneously (under the skin) 15 to 30 minutes before a meal. Proper injection technique and site rotation are essential to prevent localized skin issues. Always keep a fast-acting sugar source nearby in case of hypoglycemia. Consult your doctor for dosage adjustments based on your physical activity and dietary habits to ensure appropriate glycemic control.

Huminsulin 40/60 40 IU Injection 10 ML is used for the following:

Managing blood sugar levels in Type 1 diabetes
Controlling glucose levels in Type 2 diabetes
Providing both short-term and long-term insulin coverage
Simulating natural insulin patterns in diabetic patients
Preventing diabetic complications from uncontrolled sugar levels
Supporting insulin needs during illness or stress
Balancing blood glucose before and after meals

Follow these instructions while administering Huminsulin 40/60 40 IU Injection 10 ML:

Gently roll the vial between your palms before use.
Administer subcutaneously in the abdomen, thigh, or upper arm.
Rotate injection sites within the same region regularly.
Administer 15-30 minutes before meals.

Huminsulin 40/60 40 IU Injection 10 ML is administered subcutaneously.

Huminsulin 40/60 40 IU Injection 10 ML may have the following common side effects:

Hypoglycemia: This occurs when your blood sugar drops too low, causing symptoms like sweating, dizziness, tremors, hunger, confusion, and headache.
Injection site reactions: You may experience pain, redness, or swelling when you inject the insulin.
Weight gain
Allergic reactions
Sodium retention: This happens when your body holds onto extra sodium, which can sometimes lead to fluid buildup.
Edema refers to swelling caused by excess fluid trapped in the body's tissues, often noticed in the ankles, feet, and legs.

Management Of Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Huminsulin 40/60 40 IU Injection 10 ML. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some ways to manage common side effects:

Hypoglycemia: Administer Huminsulin 40/60 40 IU Injection 10 ML 15-30 minutes before meals to help prevent low blood sugar episodes.
Injection site reactions: Rotate your injection sites within the same body region to reduce pain, redness, or swelling.

Huminsulin 40/60 40 IU Injection 10 ML contains Human Premix Insulin (40 IU), which works on the body as follows:

Glucose uptake enhancement: The insulin in this medicine binds to specific receptors on cell surfaces, particularly in muscle and fat tissues, facilitating the movement of glucose from the bloodstream into these cells and thus reducing blood glucose levels.
Liver glucose production inhibition: It prevents your liver from producing and releasing excessive glucose into the bloodstream, contributing to better blood sugar control.
Protein synthesis promotion: Insulin helps your body build proteins by enhancing amino acid transport into cells and stimulating protein synthesis, supporting proper tissue maintenance and growth.
Fat metabolism regulation: It promotes the storage of fat and inhibits the breakdown of fat stores, helping maintain balanced energy metabolism in your body.

Pregnancy

Caution is advised while taking Huminsulin 40/60 40 IU Injection 10 ML if pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Huminsulin 40/60 40 IU Injection 10 ML if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Alcohol may affect your blood sugar levels when you are using Huminsulin 40/60 40 IU Injection 10 ML. It can increase the risk of hypoglycaemia (low blood sugar). Consider avoiding alcohol or discuss with your doctor how to manage your insulin dose if you plan to drink.

Liver

Caution is advised while taking Huminsulin 40/60 40 IU Injection 10 ML if you have liver problems. Your liver helps regulate blood glucose levels, and liver impairment may affect how your body responds to insulin. Your doctor may need to adjust your dosage.

Kidney

Caution is advised before using Huminsulin 40/60 40 IU Injection 10 ML if you have a history of any kidney problems. Kidney function can affect insulin requirements, and you may need dose adjustments. It is a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

Hypoglycaemia (low blood sugar) can affect your ability to concentrate and react. This may be dangerous when driving or operating machinery. Be aware of your blood sugar levels before such activities, and carry a quick source of sugar with you.

Allergy

If you have a known allergy to human insulin or any ingredients in Huminsulin 40/60 40 IU Injection 10 ML, do not use this medicine. Tell your doctor about any previous allergic reactions to insulin products before starting treatment.

Children

Caution is advised when administering Huminsulin 40/60 40 IU Injection 10 ML to children. The safety and effectiveness in children may vary, and insulin requirements change during growth phases. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Huminsulin 40/60 40 IU Injection 10 ML under medical supervision as they may be more susceptible to its side effects, particularly hypoglycaemia. Your doctor will guide you based on your health status and may recommend more frequent blood sugar monitoring.

Drug-Drug Interactions

Huminsulin 40/60 40 IU Injection 10 ML interacts with the following medicines:

Corticosteroids: Medicines like prednisolone and dexamethasone can reduce the effectiveness of Huminsulin 40/60 40 IU Injection 10 ML, potentially causing higher blood sugar levels.
Beta-blockers: Medicines such as propranolol and atenolol may mask low blood sugar warning signs, making it harder to recognise hypoglycaemia.
Thiazide diuretics: Water tablets like bendroflumethiazide and indapamide can decrease the blood sugar-lowering effect of Huminsulin 40/60 40 IU Injection 10 ML.
Oral contraceptives: Birth control medicines like ethinylestradiol combinations may reduce insulin sensitivity, requiring dose adjustments of Huminsulin 40/60 40 IU Injection 10 ML.
Thyroid hormones: Medicines such as levothyroxine can affect glucose metabolism, potentially altering your insulin requirements.

Drug-Food Interactions

Huminsulin 40/60 40 IU Injection 10 ML has minimal direct food interactions, but meal timing affects its action.

Carbohydrates: Foods high in carbohydrates can raise blood sugar levels rapidly, requiring careful coordination with Huminsulin 40/60 40 IU Injection 10 ML administration.

Drug-Disease Interactions

Huminsulin 40/60 40 IU Injection 10 ML interacts with the following diseases:

Renal impairment: Patients with kidney problems may experience prolonged insulin action, requiring careful dose monitoring and possible reduction.
Hepatic impairment: Liver disease can affect glucose metabolism, potentially altering insulin requirements and response to Huminsulin 40/60 40 IU Injection 10 ML.
Diabetic ketoacidosis: Huminsulin 40/60 40 IU Injection 10 ML is not suitable for treating this acute complication of diabetes, which requires immediate medical attention.

Daily Dose

The daily dose of Huminsulin 40/60 40 IU Injection 10 ML should be administered as prescribed by your doctor. The dosage may vary based on your blood sugar levels, body weight, and response to treatment. It's important to follow the prescribed dosage without making changes on your own.

Over Dose

Taking too much Huminsulin 40/60 40 IU Injection 10 ML can cause hypoglycaemia (low blood sugar). You might feel sweaty, dizzy, shaky, hungry, confused, or develop a headache. If these symptoms occur, consume something sugary and contact your doctor.

Missed Dose

If you forget to administer Huminsulin 40/60 40 IU Injection 10 ML, do it as soon as you remember. If it's nearly time for your next dose, skip the missed one and resume your regular schedule. Never increase your dosage to make up for missed doses.

Store unused Huminsulin 40/60 40 IU Injection 10 ML in a refrigerator between 2°C to 8°C (never in the freezer).
Once opened, you can keep the vial at room temperature (below 25°C) for up to 4 weeks.
Protect from direct heat and light.
Keep all medicines out of sight and reach of children.
Do not use after the expiry date printed on the label.

Monitor your carbohydrate intake consistently and try to eat meals at regular times to help maintain steady blood glucose levels throughout the day.
Regularly engage in moderate physical activity, such as walking for 30 minutes daily, as exercise helps improve insulin sensitivity and control blood sugar.

Fact Box

Dosage Forms Available	Premix Insulin Injection
Habit Forming	No
Ailment	Diabetes mellitus, Hyperglycaemia
Drug Category	Glucose metabolism regulator
Therapeutic Category	Antidiabetic

Can I mix Huminsulin 40/60 40 IU Injection 10 ML with other insulins?

You should not mix this insulin with other types in the same syringe. Use Huminsulin 40/60 40 IU Injection 10 ML exactly as prescribed by your doctor.

How should I store Huminsulin 40/60 40 IU Injection 10 ML?

Unopened vials should be stored in the refrigerator (2°C to 8°C). Once in use, they should be kept below 25°C for up to 4 weeks. Never freeze insulin.

What happens if I miss a dose?

Take it as soon as you remember. If it's almost time for your next dose, skip the missed one. Never take a double dose.

How quickly does Huminsulin 40/60 40 IU Injection 10 ML work?

It starts working within 15-30 minutes after injection. This is why you should administer it shortly before meals.

What are the signs of low blood sugar?

Watch for sweating, dizziness, shakiness, hunger, confusion, and headache. These symptoms mean your blood glucose (sugar) is too low.

How do I administer Huminsulin 40/60 40 IU Injection 10 ML correctly?

Inject it under the skin (subcutaneously) of your abdomen, thigh, or upper arm. Rotate injection sites to prevent tissue damage.

Can I use Huminsulin 40/60 40 IU Injection 10 ML during illness?

You should continue insulin during illness, but your needs may change. Monitor your blood sugar closely and consult your doctor for guidance.

Last Updated On 18 Mar. 2026 | 7:16PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 9 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

Expiry on or after: August 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. Food and Drug Administration. (2019). Clinical pharmacology and biopharmaceutics review(s): NDA 208157. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/208157Orig1s000PharmR.pdf (Accessed 1 April 2025)
Human insulin injection: MedlinePlus drug information. (2019, October 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682611.html
Insulin human. (2025, May 2). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00030
Human insulin - StatPearls - NCBI bookshelf. (2023, August 28). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK545190/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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