Glysafe G 2/500 MG Tablet 10: Uses, Side Effects, Price & Substitutes

About Glysafe G 2/500 Mg Tablet 10

Glysafe G 2/500 Mg Tablet 10 is a diabetes medicine used to manage high blood sugar in adults with type 2 diabetes when a single medicine is not enough. It is a combination medicine containing glimepiride (helps the pancreas release insulin) and metformin (helps the body respond better to insulin), and belongs to classes of medicines called sulfonylureas and biguanides.

This medicine works by prompting the pancreas to release more insulin and by helping the body use insulin better and make less sugar in the liver, which keeps blood sugar steadier through the day. The metformin is in a sustained-release form, so swallow the tablet whole without crushing or chewing, just before or with a main meal, and take it regularly as prescribed.

A balanced diet with regular meals, regular physical activity and routine blood sugar monitoring are important alongside this medicine. Do not skip meals, and carry a sugary snack in case your blood sugar drops suddenly.

Before taking this medicine, tell your doctor if you have kidney or liver problems, a history of low blood sugar, or are due for a scan with contrast dye or surgery, and limit alcohol. Low blood sugar (shakiness, sweating, confusion) can occur, and extreme tiredness with fast breathing or stomach pain can rarely signal lactic acidosis, so seek urgent medical help.

Fact Box

Dosage Forms Available

Tablet

Habit Forming

Ailment

Type 2 diabetes mellitus

Drug Category

Active ingredients: Glimepiride (2 mg) + Metformin (500 mg)
Dosage form: Tablet
Drug class: Sulfonylurea plus biguanide, antidiabetic medicines
Used for: Type 2 diabetes mellitus
Prescription required: Yes
Habit forming: No

Therapeutic Category

Antidiabetic

Frequently Asked Questions (FAQs)

What is Glysafe G 2/500 Mg Tablet 10 used for?

Glysafe G 2/500 Mg Tablet 10 is used to help control blood sugar levels in adults with type 2 diabetes mellitus, along with diet and exercise.

How does Glysafe G 2/500 Mg Tablet 10 work?

Glimepiride helps the pancreas release more insulin, while metformin reduces the amount of sugar produced by the liver and improves the body's response to insulin.

Can I chew or crush Glysafe G 2/500 Mg Tablet 10 before taking it?

No. Swallow it whole with water. Crushing or chewing can affect how it works.

What are the common side effects of Glysafe G 2/500 Mg Tablet 10?

Common side effects may include low blood sugar, nausea, diarrhoea, stomach discomfort and headache. Consult your doctor if any side effects persist or become troublesome.

Can I drink alcohol while taking Glysafe G 2/500 Mg Tablet 10?

Alcohol may affect blood sugar control and increase the risk of low blood sugar and lactic acidosis. Consult your doctor about alcohol consumption while taking this medicine.

Can Glysafe G 2/500 Mg Tablet 10 be used during pregnancy or breastfeeding?

Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before taking this medicine. Your doctor will advise whether this treatment is suitable for you.

How should I store my Glysafe G 2/500 Mg Tablet 10?

Store it below 25°C, in a dry place away from light and moisture, and out of the reach of children.

References

DailyMed. (n.d.). Amaryl- glimepiride tablet. U.S. National Library of Medicine. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
Langtry HD, Balfour JA. Glimepiride. A review of its use in the management of type 2 diabetes mellitus. Drugs. 1998;55(4):563-584. https://pubmed.ncbi.nlm.nih.gov/9561345/
Food and Drug Administration. (n.d.). Full prescribing information: Amaryl. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
DrugBank. (n.d.). Metformin. Retrieved April 1, 2024, from https://go.drugbank.com/drugs/DB00331

Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.