Epidosin Injection is used to relieve spasms of smooth muscles in the urinary and biliary tract and during certain medical procedures. It belongs to the class of medicines known as antispasmodic agents.
This medicine is commonly prescribed to relieve painful spasms associated with conditions such as renal colic, ureteric colic, and biliary colic. It may also be used during labour or certain diagnostic procedures to help relax smooth muscles and reduce discomfort.
This injection is administered by a healthcare professional. Inform your doctor if you have glaucoma, heart disease, or prostate enlargement before receiving this medicine. Continue treatment only as advised by your doctor.
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Epidosin 8 MG Injection 20 ML
- AMPOULE of 1 ML
- Pack of 20 ML
Old MRP ₹1255
MRP ₹1176.56
₹941.25
₹58.83/ML
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CompositionAbout Epidosin 8 MG Injection 20 ML
Uses of Epidosin 8 MG Injection 20 ML
Epidosin Injection is used for:
- Relief of urinary tract spasms
- Relief of renal colic pain
- Relief of biliary colic
- Reduction of smooth muscle spasms during medical procedures
- Facilitation of cervical dilatation during labour when prescribed
Directions for Use of Epidosin 8 MG Injection 20 ML
Administer Epidosin Injection in the following manner:
This medicine should only be administered by a healthcare professional.
It's important to ensure that Epidosin Injection is not self-administered at home.
The injection process usually happens in a hospital or clinic setting.
The medicine is given either intramuscularly or as a slow intravenous injection.
For specific advice on how to use this medicine, always consult your doctor.
Route of Administration
Epidosin Injection is administered intramuscularly or via intravenous injection.
Side Effects of Epidosin 8 MG Injection 20 ML
Epidosin Injection may cause effects such as:
- Dry mouth
- Dizziness
- Blurred vision
- Fast heartbeat
- Nausea
Managing the Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Epidosin Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- Dry mouth: Sip water frequently to reduce dryness.
- Dizziness: Rest until you feel better and avoid sudden movements.
How Epidosin 8 MG Injection 20 ML Works?
Epidosin Injection contains valethamate (8 mg). The activity of this medicine is as follows:
Anticholinergic Action: Valethamate bromide works by inhibiting the action of acetylcholine - a chemical messenger responsible for contraction of smooth muscles. By blocking acetylcholine, it reduces the contractions of these muscles.
Spasmolytic Action: Valethamate helps in relieving spasms and associated pain in organs composed of smooth muscles such as intestines, cervix, urinary tract and bile duct. This relaxation leads to pain relief in conditions like dysmenorrhoea and renal colic.
Cervical Dilation: During labour, valethamate aids in cervical dilation thereby facilitating childbirth.
Safety Measures & Warnings
Pregnancy
Caution is advised while being administered Epidosin Injection if you're pregnant. It's best to consult your doctor before receiving this medicine.
Breastfeeding
Epidosin Injection should be used during breastfeeding only if prescribed by a doctor. It is essential to consult your doctor to understand potential risks to the infant before receiving this medication.
Alcohol
Avoid alcohol consumption while taking this medicine as it can increase side effects such as drowsiness, dizziness, or blurred vision.
Liver
If you have mild to moderate liver issues, caution is advised when Epidosin Injection is administered. This medicine may affect liver function. Discuss these concerns with your doctor before starting this medication.
Kidney
Epidosin Injection should be used with caution if you have a history of kidney problems. Consulting your doctor before starting this medication is advisable.
Using Machines & Driving
Since Epidosin Injection can cause drowsiness and blurred vision, avoid driving or operating heavy machinery after its administration.
Allergy
If you are allergic to Valethamate or any other components present in Epidosin Injection, avoid its use. Discuss this with your doctor before administration.
Children
Epidosin Injection is meant for adult use. Always consult your doctor before giving any medicine to a child under 18 years of age.
Older Patients
Caution is advised when Epidosin Injection is given to older patients. It should be used carefully as older adults may be more sensitive to anticholinergic effects such as dry mouth, constipation, urinary retention, and blurred vision, especially if they have other medical conditions or take multiple medicines.
Interactions of Epidosin 8 MG Injection 20 ML
Drug-Drug Interactions
Epidosin Injection interacts with the following medicines:
- Antipsychotics: Concomitant use of antipsychotics like risperidone or olanzapine may increase the risk of anticholinergic side effects.
- Antihistamines: Medicines such as cetirizine or loratadine may interact, potentially exacerbating symptoms like dry mouth and blurred vision.
- Antispasmodics: When administered with antispasmodics like mebeverine and dicyclomine, Epidosin Injection may enhance the anticholinergic effects.
- Tricyclic antidepressants: Co-administration with medicines like amitriptyline or imipramine could increase the anticholinergic effect.
- MAO inhibitors: Interactions with medicines like phenelzine or tranylcypromine may increase the side effects of Epidosin Injection.
- Opioid analgesics: Medicines like morphine or oxycodone may interact, potentially enhancing side effects such as constipation and urinary retention.
Drug-Food Interactions
No known specific food items have been reported to interact with Epidosin Injection.
Drug-Disease Interactions
Epidosin Injection interacts with the following diseases:
Severe liver or kidney dysfunction: This medicine might worsen the condition in patients suffering from severe liver or kidney disease.
Autonomic neuropathy: It should be used cautiously in patients with autonomic neuropathy due to a potential increase in side effects.
Hyperthyroidism: Patients diagnosed with hyperthyroidism may experience an exaggerated response to Epidosin Injection.
Coronary heart disease and Hypertension: Those diagnosed with these diseases should be cautious, as this medication can potentially increase heart rate.
Dosage of Epidosin 8 MG Injection 20 ML
Daily Dose
The daily dose of Epidosin Injection should be administered as directed by your doctor. The dosage may vary depending on your personal health conditions and how you respond to the medication. Always follow your doctor's instructions and never exceed the prescribed dosage.
Over Dose
If too much Epidosin Injection is administered, you might experience symptoms like severe dry mouth, blurred vision, and rapid heartbeat. If this happens, it's important to inform your doctor right away.
Missed Dose
If you happen to miss a dose of Epidosin Injection, receive it as soon as you remember. However, if it's nearly time for your next dose, let go of the missed one and continue with your regular dosage schedule. Always consult your doctor before making any changes to the dosage.
Storage
- Store Epidosin Injection at room temperature, ideally between 15°C to 25°C.
- Keep the medicine away from direct light and moisture.
- Always keep this product out of reach of children.
Diet & Lifestyle
If you're experiencing painful menstruation, try a diet rich in calcium and magnesium, like green leafy vegetables and nuts, which can help manage muscle spasms.
For individuals with urinary tract spasms, increase water intake to help dilute urine and potentially reduce discomfort. As always, consult your doctor for personalised advice.
Fact Box
| Available Dosage Types | Injection |
| Habit Forming | No |
| Ailment | Dysmenorrhea, Renal/Biliary Colic, Cervical Dilation |
| Drug Category | Anticholinergic, Spasmolytic |
| Therapeutic Category | Antispasmodic |
Frequently Asked Questions (FAQs)
What is Epidosin Injection used for?
Epidosin Injection is utilised for managing pain and spasms in smooth muscles, which occur in conditions such as menstrual cramps, renal/biliary colic, and during labour.
How does Epidosin work?
Epidosin contains valethamate bromide which blocks acetylcholine, a chemical that causes muscle contraction, thus helping to reduce spasms and pain by relaxing muscles.
Who administers Epidosin Injection?
Epidosin Injection should be administered by a doctor or nurse either into a muscle or into a vein; it is not meant for self-administration.
Can I take Epidosin Injection if I have kidney disease?
If you have severe kidney disease, you should avoid Epidosin Injection. Always consult your doctor before starting any new medication.
What are the possible side effects of Epidosin?
Possible side effects include dry mouth, blurred vision, rapid heartbeat, constipation and drowsiness. However, these are usually mild and temporary.
Can I drink alcohol while on Epidosin Injection?
It's best to avoid alcohol while using Epidosin Injection as it can intensify the side effects such as drowsiness and dizziness.
Is it safe to use Epidosin Injection during pregnancy?
The safety of Epidosin Injection during pregnancy has not been established. Thus, if you're pregnant, it's crucial to consult with your doctor before use.
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Manufacturer details
6, Cathedral Road Chennai – 600 086.
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: July 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- VALETHEMATE BROMIDE AND CERVICAL DILATATION. (2017, June 26). NIH NLM. Retrieved May 23, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531893/
- Valethamate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB13497
- Fixed-Dose combination of NSAIDs and spasmolytic agents in the treatment of different types of Pain—A Practical Review. (2021). National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306558/
- Sarbhjit, K., S K, B., Parmjit, K., & Surinder, B. (2013). To compare the effect of camylofin dihydrochloride (anafortin) with combination of valethamate bromide (epidosin) and hyoscine butyl-N-bormide (buscopan) on cervical dilation. Journal of clinical and diagnostic research : JCDR, 7(9), 1897–1899. https://doi.org/10.7860/JCDR/2013/6231.3345
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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