Epidosin Injection is used to relieve spasms of smooth muscles in the urinary and biliary tract and during certain medical procedures. It belongs to the class of medicines known as antispasmodic agents.
This medicine is commonly prescribed to relieve painful spasms associated with conditions such as renal colic, ureteric colic, and biliary colic. It may also be used during labour or certain diagnostic procedures to help relax smooth muscles and reduce discomfort.
This injection is administered by a healthcare professional. Inform your doctor if you have glaucoma, heart disease, or prostate enlargement before receiving this medicine. Continue treatment only as advised by your doctor.
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Epidosin 8 MG Injection 20 ML
- AMPOULE of 1 ML
- Pack of 20 ML
Old MRP ₹1255
MRP ₹1176.56
₹941.25
₹58.83/ML
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CompositionAbout Epidosin 8 MG Injection 20 ML
Uses of Epidosin 8 MG Injection 20 ML
Epidosin Injection is used for:
- Relief of urinary tract spasms
- Relief of renal colic pain
- Relief of biliary colic
- Reduction of smooth muscle spasms during medical procedures
- Facilitation of cervical dilatation during labour when prescribed
Directions for Use of Epidosin 8 MG Injection 20 ML
Administer Epidosin Injection in the following manner:
This medicine should only be administered by a healthcare professional.
It's important to ensure that Epidosin Injection is not self-administered at home.
The injection process usually happens in a hospital or clinic setting.
The medicine is given either intramuscularly or as a slow intravenous injection.
For specific advice on how to use this medicine, always consult your doctor.
Route of Administration
Epidosin Injection is administered intramuscularly or via intravenous injection.
Side Effects of Epidosin 8 MG Injection 20 ML
Epidosin Injection may cause effects such as:
- Dry mouth
- Dizziness
- Blurred vision
- Fast heartbeat
- Nausea
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Epidosin Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- Dry mouth: Sip water frequently to reduce dryness.
- Dizziness: Rest until you feel better and avoid sudden movements.
How Epidosin 8 MG Injection 20 ML Works?
Epidosin Injection contains valethamate (8 mg). The activity of this medicine is as follows:
Anticholinergic Action: Valethamate bromide works by inhibiting the action of acetylcholine - a chemical messenger responsible for contraction of smooth muscles. By blocking acetylcholine, it reduces the contractions of these muscles.
Spasmolytic Action: Valethamate helps in relieving spasms and associated pain in organs composed of smooth muscles such as intestines, cervix, urinary tract and bile duct. This relaxation leads to pain relief in conditions like dysmenorrhoea and renal colic.
Cervical Dilation: During labour, valethamate aids in cervical dilation thereby facilitating childbirth.
Safety Measures & Warnings
Pregnancy
Caution is advised while being administered Epidosin Injection if you're pregnant. It's best to consult your doctor before receiving this medicine.
Breastfeeding
Epidosin Injection should be used during breastfeeding only if prescribed by a doctor. It is essential to consult your doctor to understand potential risks to the infant before receiving this medication.
Alcohol
Avoid alcohol consumption while taking this medicine as it can increase side effects such as drowsiness, dizziness, or blurred vision.
Liver
If you have mild to moderate liver issues, caution is advised when Epidosin Injection is administered. This medicine may affect liver function. Discuss these concerns with your doctor before starting this medication.
Kidney
Epidosin Injection should be used with caution if you have a history of kidney problems. Consulting your doctor before starting this medication is advisable.
Use In Driving And Operating Machinery
Since Epidosin Injection can cause drowsiness and blurred vision, avoid driving or operating heavy machinery after its administration.
Allergy
If you are allergic to Valethamate or any other components present in Epidosin Injection, avoid its use. Discuss this with your doctor before administration.
Children
Epidosin Injection is meant for adult use. Always consult your doctor before giving any medicine to a child under 18 years of age.
Older Patients
Caution is advised when Epidosin Injection is given to older patients. It should be used carefully as older adults may be more sensitive to anticholinergic effects such as dry mouth, constipation, urinary retention, and blurred vision, especially if they have other medical conditions or take multiple medicines.
Interactions of Epidosin 8 MG Injection 20 ML
Drug-Drug Interactions
Epidosin Injection interacts with the following medicines:
- Antipsychotics: Concomitant use of antipsychotics like risperidone or olanzapine may increase the risk of anticholinergic side effects.
- Antihistamines: Medicines such as cetirizine or loratadine may interact, potentially exacerbating symptoms like dry mouth and blurred vision.
- Antispasmodics: When administered with antispasmodics like mebeverine and dicyclomine, Epidosin Injection may enhance the anticholinergic effects.
- Tricyclic antidepressants: Co-administration with medicines like amitriptyline or imipramine could increase the anticholinergic effect.
- MAO inhibitors: Interactions with medicines like phenelzine or tranylcypromine may increase the side effects of Epidosin Injection.
- Opioid analgesics: Medicines like morphine or oxycodone may interact, potentially enhancing side effects such as constipation and urinary retention.
Drug-Food Interactions
No known specific food items have been reported to interact with Epidosin Injection.
Drug-Disease Interactions
Epidosin Injection interacts with the following diseases:
Severe liver or kidney dysfunction: This medicine might worsen the condition in patients suffering from severe liver or kidney disease.
Autonomic neuropathy: It should be used cautiously in patients with autonomic neuropathy due to a potential increase in side effects.
Hyperthyroidism: Patients diagnosed with hyperthyroidism may experience an exaggerated response to Epidosin Injection.
Coronary heart disease and Hypertension: Those diagnosed with these diseases should be cautious, as this medication can potentially increase heart rate.
Dosage of Epidosin 8 MG Injection 20 ML
Daily Dose
The daily dose of Epidosin Injection should be administered as directed by your doctor. The dosage may vary depending on your personal health conditions and how you respond to the medication. Always follow your doctor's instructions and never exceed the prescribed dosage.
Over Dose
If too much Epidosin Injection is administered, you might experience symptoms like severe dry mouth, blurred vision, and rapid heartbeat. If this happens, it's important to inform your doctor right away.
Missed Dose
If you happen to miss a dose of Epidosin Injection, receive it as soon as you remember. However, if it's nearly time for your next dose, let go of the missed one and continue with your regular dosage schedule. Always consult your doctor before making any changes to the dosage.
Storage
- Store Epidosin Injection at room temperature, ideally between 15°C to 25°C.
- Keep the medicine away from direct light and moisture.
- Always keep this product out of reach of children.
Special Dietary And Lifestyle Recommendation
If you're experiencing painful menstruation, try a diet rich in calcium and magnesium, like green leafy vegetables and nuts, which can help manage muscle spasms.
For individuals with urinary tract spasms, increase water intake to help dilute urine and potentially reduce discomfort. As always, consult your doctor for personalised advice.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Dysmenorrhea, Renal/Biliary Colic, Cervical Dilation |
| Drug Category | Anticholinergic, Spasmolytic |
| Therapeutic Category | Antispasmodic |
Frequently Asked Questions (FAQs)
What is Epidosin Injection used for?
Epidosin Injection is utilised for managing pain and spasms in smooth muscles, which occur in conditions such as menstrual cramps, renal/biliary colic, and during labour.
How does Epidosin work?
Epidosin contains valethamate bromide which blocks acetylcholine, a chemical that causes muscle contraction, thus helping to reduce spasms and pain by relaxing muscles.
Who administers Epidosin Injection?
Epidosin Injection should be administered by a doctor or nurse either into a muscle or into a vein; it is not meant for self-administration.
Can I take Epidosin Injection if I have kidney disease?
If you have severe kidney disease, you should avoid Epidosin Injection. Always consult your doctor before starting any new medication.
What are the possible side effects of Epidosin?
Possible side effects include dry mouth, blurred vision, rapid heartbeat, constipation and drowsiness. However, these are usually mild and temporary.
Can I drink alcohol while on Epidosin Injection?
It's best to avoid alcohol while using Epidosin Injection as it can intensify the side effects such as drowsiness and dizziness.
Is it safe to use Epidosin Injection during pregnancy?
The safety of Epidosin Injection during pregnancy has not been established. Thus, if you're pregnant, it's crucial to consult with your doctor before use.
What is the primary active component in Epidosin Injection?
Epidosin Injection contains valethamate bromide. It is the active ingredient that works by relaxing smooth muscles to relieve painful spasms and discomfort in various body organs.
How should Epidosin Injection be stored according to the label?
Store Epidosin Injection below 25°C and protect from light and moisture to ensure the medicine remains effective.
Is Epidosin Injection safe for mothers who are breastfeeding?
Epidosin Injection should be used during breastfeeding only if prescribed by a doctor. It is essential to consult your doctor to understand potential risks to the infant before receiving this specific medication.
Can Epidosin Injection cause significant drowsiness?
Epidosin Injection may cause side effects such as dizziness or blurred vision. If you feel unwell after receiving it, consult a doctor for advice.
How is Epidosin Injection administered by medical professionals?
Epidosin Injection is given by healthcare experts either as an intramuscular injection or intravenous injection. It is never meant for self-administration at home.
Can I safely drive after receiving Epidosin Injection?
Avoid driving or operating heavy machinery after receiving Epidosin Injection. It can cause dizziness or blurred vision, which may affect your ability to drive safely.
Is Epidosin Injection effective for treating kidney stone pain?
No, Epidosin Injection is not specifically indicated for kidney stone pain. It is used to relieve smooth muscle spasms as prescribed by a doctor.
Can Epidosin Injection be used for gallbladder pain?
Epidosin Injection is used to treat biliary colic, also known as gallbladder pain. It works by relaxing the smooth muscles of the bile duct to ease discomfort.
What precautions apply to Epidosin Injection for patients with liver issues?
Caution is advised if you have liver problems when receiving Epidosin Injection. Limited safety data are available in patients with liver impairment, so the doctor may monitor your condition if needed. So discuss any concerns with your doctor before administration.
Can Epidosin Injection interact with common antihistamines?
Epidosin Injection may interact with antihistamines like cetirizine. It could potentially increase anticholinergic side effects such as dry mouth and blurred vision when these medicines are taken together.
Is Epidosin Injection suitable for use in children?
Epidosin Injection is primarily intended for adult use. It should be given to children under 18 years of age only if prescribed by a doctor after careful evaluation.
What should be done if a scheduled dose of Epidosin Injection is missed?
Since Epidosin Injection is administered by a healthcare professional, a missed dose is unlikely. If you miss an appointment for the injection, contact your doctor or healthcare provider to reschedule.
Can Epidosin Injection interact with tricyclic antidepressants?
Epidosin Injection may interact with tricyclic antidepressants like amitriptyline. This combination may increase anticholinergic side effects such as dry mouth, constipation, blurred vision, and difficulty urinating.
How does Epidosin Injection assist during the labour process?
Epidosin Injection aids in cervical dilation during labour. It facilitates the opening of the cervix, which helps in the childbirth process by relaxing the relevant smooth muscles.
Does Epidosin Injection interact with MAO inhibitors?
Epidosin Injection may interact with medicines that have anticholinergic effects, but a specific interaction with MAO inhibitors is not well established. Inform your doctor about all medicines you are taking before receiving the injection.
Can Epidosin Injection interact with opioid pain medications?
Epidosin Injection may interact with opioids like morphine. This combination may increase side effects such as constipation, urinary retention, and drowsiness.
Are there specific dietary tips for painful periods while using Epidosin Injection?
Maintaining a balanced diet that includes adequate calcium and magnesium may support overall muscle function while receiving Epidosin Injection for menstrual pain. Dietary measures support general health but do not directly enhance the effect of the injection.
What lifestyle advice helps urinary spasms when receiving Epidosin Injection?
Increase your water intake if you are receiving Epidosin Injection for urinary tract spasms. It helps maintain urinary health and may reduce irritation alongside medical treatment.
Can Epidosin Injection affect patients diagnosed with hyperthyroidism?
Patients with hyperthyroidism may be more sensitive to anticholinergic effects, such as increased heart rate, when receiving Epidosin Injection. It is important to discuss your medical history with a doctor before receiving this injection.
Is caution required for patients with high blood pressure receiving Epidosin Injection?
Those with hypertension should be cautious when receiving Epidosin Injection. It may increase heart rate or cause mild changes in blood pressure, so medical supervision is necessary during its administration.
Are there special considerations for older patients receiving Epidosin Injection?
Caution is advised when Epidosin Injection is given to older patients. It should be used carefully as older adults may be more sensitive to anticholinergic effects such as dry mouth, constipation, urinary retention, and blurred vision, especially if they have other medical conditions or take multiple medicines.
What symptoms occur if too much Epidosin Injection is administered?
Overdose of Epidosin Injection can cause severe dry mouth, blurred vision, and rapid heartbeat. It is vital to inform your doctor immediately if these symptoms occur.
Does Epidosin Injection interact with antispasmodic medicines?
Epidosin Injection may interact with other anticholinergic antispasmodic medicines such as dicycloverine. This combination may increase side effects such as dry mouth, constipation, blurred vision, and urinary retention.
Should I be concerned about nausea after receiving Epidosin Injection?
Nausea may occur in some patients after receiving Epidosin Injection. If nausea becomes persistent or troublesome, consult your doctor.
Can I self-administer Epidosin Injection at my home?
Epidosin Injection must only be administered by a healthcare professional in a hospital or clinic setting. It is not designed or safe for self-administration at home.
Does Epidosin Injection cause changes in vision?
Epidosin Injection can cause common side effects like blurred vision. It is important to be aware of this and avoid tasks requiring clear sight after administration.
Can Epidosin Injection interact with antipsychotic medications?
Epidosin Injection interacts with antipsychotics like risperidone. This combination may increase side effects such as dry mouth, constipation, blurred vision, and urinary retention.
Is Epidosin Injection known to be habit-forming?
Epidosin Injection is not considered a habit-forming medicine. It is used relieve smooth muscle spasms under medical supervision.
When should I seek medical advice regarding side effects from Epidosin Injection?
Consult your doctor if side effects from Epidosin Injection, like persistent vomiting, severe dryness of mouth, fast heartbeat, or blurred visionbecome troublesome. Report any worsening symptoms to your healthcare provider.
Where is the appropriate setting to receive Epidosin Injection?
Epidosin Injection should be received in a professional healthcare setting like a hospital. It is administered by qualified staff to ensure safety and correct dosage delivery.
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Manufacturer details
6, Cathedral Road Chennai – 600 086.
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: August 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- VALETHEMATE BROMIDE AND CERVICAL DILATATION. (2017, June 26). NIH NLM. Retrieved May 23, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531893/
- Valethamate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB13497
- Fixed-Dose combination of NSAIDs and spasmolytic agents in the treatment of different types of Pain—A Practical Review. (2021). National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306558/
- Sarbhjit, K., S K, B., Parmjit, K., & Surinder, B. (2013). To compare the effect of camylofin dihydrochloride (anafortin) with combination of valethamate bromide (epidosin) and hyoscine butyl-N-bormide (buscopan) on cervical dilation. Journal of clinical and diagnostic research : JCDR, 7(9), 1897–1899. https://doi.org/10.7860/JCDR/2013/6231.3345
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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