Doxoril 400 Mg Tablet 10

Macleods Pharmaceuticals Pvt.Ltd

Pack of 10 Units

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Composition

Doxofylline (400 Mg)

Strength:

400 MG 200 MG

Doxoril 400 mg Tablet 10 is used to manage asthma maintenance. It is a single-ingredient bronchodilator medicine containing doxofylline.

This medicine controls daily symptoms and reduces frequency of asthma flare-ups. It also eases chronic breathlessness and chest tightness in chronic obstructive pulmonary disease. It also prevents sudden narrowing of the airways to improve overall lung function.

Before starting, tell your doctor about your medical conditions and allergies. Tell the doctor about all other medicines, supplements or herbal products you take. Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding. Report persistent or serious side effects to your doctor. Do not stop taking or using the medicine unless your doctor advises you to do so.

Doxoril 400 mg Tablet 10 is used to manage asthma maintenance.

Uses of Doxoril 400 mg Tablet 10 are:

Asthma Maintenance: Controls daily symptoms and reduces frequency of asthma flare-ups.
COPD Management: Eases chronic breathlessness and chest tightness in chronic obstructive pulmonary disease.
Airway Spasm Prevention: Prevents sudden narrowing of the airways to improve overall lung function.

Here's how to take Doxoril 400 Mg Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush or chew it.
It can be taken with or without food.
Regular use will provide maximum benefit. Do not stop its usage without consulting your doctor.
If you find it difficult to swallow the tablet whole, consult your doctor regarding alternative formulations.

Doxoril 400 Mg Tablet 10is taken orally.

Doxoril 400 mg Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Doxoril 400 mg Tablet 10:

Digestive: feeling sick (nausea), vomiting, stomach pain and loose motions (diarrhoea).
Neurological: headache, dizziness, restlessness, difficulty sleeping (insomnia) and tremor. Rising slowly from sitting or lying down can help reduce dizziness.
Cardiovascular: a fast or irregular heartbeat (palpitations).
Circulatory: flushing.
Urinary: passing urine more often.

If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Doxoril 400 Mg Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some ways to manage common side effects:

Stomach Pain: Try taking Doxoril 400 Mg Tablet 10 with food or milk.
Insomnia: Consider taking this medicine in the morning if it causes trouble sleeping at night.

Doxoril 400 Mg Tablet 10 contains doxofylline (400 mg). Doxofylline is a xanthine-derivative bronchodilator that inhibits several phosphodiesterase (PDE) isoenzymes, leading to increased intracellular cyclic AMP (cAMP) levels in airway smooth muscle. The rise in cAMP relaxes bronchial smooth muscle (bronchodilation) and may reduce airway inflammation. Compared with theophylline, doxofylline has less activity at adenosine receptors and typically causes fewer central nervous system and cardiac stimulant effects.

Pregnancy

Caution is advised while taking Doxoril 400 Mg Tablet 10if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, please discuss this with your doctor before starting Doxoril 400 Mg Tablet 10. Understanding potential risks and benefits is essential.

Alcohol

Mixing alcohol with this medication may increase the risk of CNS side effects such as restlessness and insomnia. Consult your doctor for advice on alcohol consumption while taking Doxoril 400 Mg Tablet 10.

Liver

If you have liver issues, be cautious when starting Doxoril 400 Mg Tablet 10. It is contraindicated in severe liver impairment. This medicine may affect liver function, so discussing your health status with your doctor is recommended.

Kidney

Doxoril 400 Mg Tablet 10 should be used with caution if you have any kidney problems. Dosage adjustment may be required. Your doctor will guide you based on your health status.

Use In Driving And Operating Machinery

Doxoril 400 Mg Tablet 10may cause dizziness or tiredness which could affect your ability to drive or operate machinery. Be sure to know how you react to the medicine before engaging in such activities.

Allergy

Avoid using Doxoril 400 Mg Tablet 10if you are allergic to doxofylline or any other xanthine derivatives. If you experience any allergic reactions, seek immediate medical help.

Children

Doxoril 400 Mg Tablet 10 should be used in children only when prescribed by a child’s doctor. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Doxoril 400 Mg Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Doxoril 400 Mg Tablet 10 interacts with the following medicines:

Antibiotics: Medicines like ciprofloxacin and erythromycin can increase levels of doxofylline in the blood, potentially escalating side effects.
Antidepressants: Fluvoxamine can interact with Doxoril 400 Mg Tablet 10, leading to increased levels of doxofylline in your body, which might amplify side effects.
Antiarrhythmics: When taken alongside Doxoril 400 Mg Tablet 10, mexiletine could elevate blood concentrations of doxofylline, increasing the risk of side effects.

Drug-Food Interactions

Doxoril 400 Mg Tablet 10 interacts with the following foods:

Caffeine: Consuming large amounts of caffeine or chocolate while taking Doxoril 400 Mg Tablet 10can increase side effects like restlessness and insomnia.

Drug-Disease Interactions

Doxoril 400 Mg Tablet 10 interacts with the following diseases:

Peptic Ulcer Disease: If you have a history of peptic ulcers, using Doxoril 400 Mg Tablet 10could worsen your condition due to its potential gastrointestinal side effects.
Seizure Disorders: This medicine might exacerbate seizure disorders as it has been associated with an increased risk of seizures in susceptible individuals.
Hypertension: This medication might further increase blood pressure due to its cardiovascular side effects.

Daily Dose

It's crucial that you take Doxoril 400 Mg Tablet 10 as prescribed by your doctor. The dosage can vary based on individual factors, such as how severe your condition is and how you respond to the medicine. Always follow the dosage prescribed and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Doxoril 400 Mg Tablet 10, you may experience symptoms like nausea, vomiting, stomach pain, restlessness, tremor, rapid heartbeat, palpitations, dizziness and headache. Severe overdose may cause seizures, arrhythmias, hypotension and respiratory depression. Seek urgent medical attention if severe symptoms or collapse occur.

Missed Dose

In case you forget to take a dose of Doxoril 400 Mg Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase your dose without consulting your doctor.

Store Doxoril 400 Mg Tablet 10 at a cool room temperature between 20°C to 25°C.
Keep it away from light, heat and moisture to maintain its efficacy.
Always ensure Doxoril 400 Mg Tablet 10 is stored out of reach from children and pets for safety.

If you're prescribed Doxoril 400 Mg Tablet 10 for asthma or COPD, try incorporating easy breathing exercises into your daily routine. This can help manage your respiratory condition by improving lung capacity.
Aim to avoid exposure to dust, smoke and other airborne allergens. These can trigger asthma attacks or worsen COPD symptoms. Regularly clean your living environment to minimise these triggers.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Asthma, COPD
Drug Category	Xanthine Derivative
Therapeutic Category	Bronchodilator

What is the primary use of Doxoril 400 Mg Tablet 10

Doxoril 400 Mg Tablet 10 is primarily used to manage respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD) by relaxing and widening the airways.

How does Doxoril 400 Mg Tablet 10 work in managing these conditions?

Doxoril 400 Mg Tablet 10 contains doxofylline, which inhibits an enzyme, leading to the relaxation of bronchial muscles and the dilation of airways, thereby reducing lung inflammation.

Can Doxoril 400 Mg Tablet 10 be used during an acute asthma attack?

No, Doxoril 400 Mg Tablet 10 is not meant for immediate relief during an acute asthma attack. It is designed for regular use to manage symptoms, not for emergency situations.

Should I take Doxoril 400 Mg Tablet 10 if I am pregnant or breastfeeding?

If you're pregnant or breastfeeding, consult your doctor before taking Doxoril 400 Mg Tablet 10 as its safety in these situations is not established yet.

Can I take Doxoril 400 Mg Tablet 10 with other medicines?

Yes, but some medicines like antibiotics, antidepressants, or antiarrhythmics might interact with doxofylline in Duphill Tablet, increasing side effects. Always inform your doctor about all medicines you're currently taking.

What if I forget to take a dose of Doxoril 400 Mg Tablet 10?

If you miss a dose, take it as soon as you remember. If it's close to your next dose time, skip the missed one and continue your normal schedule.

Can I stop taking Doxoril 400 Mg Tablet 10 once my symptoms improve?

No, discontinuing Doxoril 400 Mg Tablet 10 suddenly may worsen your symptoms. Always consult your doctor before stopping the medication, even if your symptoms have improved.

Last Updated On 15 Sep. 2026 | 1:14PM (IST)

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 7 years

MD Ayurveda

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 8 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Doxofylline: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09273
PubChem. (n.d.). Doxofylline. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/50942
Matera, M. G., Page, C., & Cazzola, M. (2017). Doxofylline is not just another theophylline! International Journal of Chronic Obstructive Pulmonary Disease/International Journal of COPD, Volume 12, 3487–3493. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723117/
Chronic obstructive pulmonary disease (COPD): MedlinePlus Medical Encyclopedia. (n.d.). https://medlineplus.gov/ency/article/000091.htm
National Library of Medicine. (n.d.). Asthma. Asthma Symptoms | Asthma Attack | MedlinePlus. https://medlineplus.gov/asthma.html

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

Telephone:09240250346

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