Rynazma 400 MG Tablet 10

Ranbaxy Laboratories Ltd

Pack of 10 Units

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MRP ~~₹57~~

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Composition

Doxofylline (400 Mg)

Rynazma 400 MG Tablet 10is primarily utilised to manage respiratory disorders such as chronic obstructive pulmonary disease (COPD) and asthma. This medicine falls under the category of bronchodilators, which are designed to ease breathing difficulties.

This medicine also helps prevent symptoms like wheezing, coughing, chest tightness, and shortness of breath. It relaxes and widens the airways in the lungs, improving airflow and making breathing easier.

You should take this medicine as directed by your doctor. Before starting this medicine, inform your doctor about any pre-existing conditions or ongoing medications. If you observe any side effects while on this medication, notify your doctor immediately. For optimal results, continue taking the medication for the duration prescribed by your doctor.

Rynazma 400 MG Tablet 10is used for the following:

Maintenance therapy to improve airflow and control symptoms in adults with asthma or chronic obstructive pulmonary disease (COPD)
Prevention of asthma attacks
Preventing bronchospasm, a sudden constriction of the airways
Reducing lung inflammation

Here's how to take Rynazma 400 MG Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush or chew it.
It can be taken with or without food.
Regular use will provide maximum benefit. Do not stop its usage without consulting your doctor.
If you find it difficult to swallow the tablet whole, consult your doctor regarding alternative formulations.

Rynazma 400 MG Tablet 10is taken orally.

Taking Rynazma 400 MG Tablet 10can result in the following common side effects:

Nausea
Vomiting
Stomach Pain
Diarrhoea
Headache
Dizziness
Restlessness: This might make you feel uneasy or anxious.
Insomnia: You may experience trouble sleeping due to this medicine.
Tremors: This refers to the involuntary shaking of body parts.
Palpitations: You may feel your heartbeat is faster or irregular.
Flushing: You could notice a sudden warmth and redness in your skin.
Increased urination: You might have to urinate more frequently than usual.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Duphill Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some ways to manage common side effects:

Stomach Pain: Try taking Rynazma 400 MG Tablet 10with food or milk.
Insomnia: Consider taking this medicine in the morning if it causes trouble sleeping at night.

Rynazma 400 MG Tablet 10 contains doxofylline (400 mg). Doxofylline is a xanthine-derivative bronchodilator that inhibits several phosphodiesterase (PDE) isoenzymes, leading to increased intracellular cyclic AMP (cAMP) levels in airway smooth muscle. The rise in cAMP relaxes bronchial smooth muscle (bronchodilation) and may reduce airway inflammation. Compared with theophylline, doxofylline has less activity at adenosine receptors and typically causes fewer central nervous system and cardiac stimulant effects.

Pregnancy

Caution is advised while taking Rynazma 400 MG Tablet 10if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, please discuss this with your doctor before starting Duphill Tablet. Understanding potential risks and benefits is essential.

Alcohol

Mixing alcohol with this medication may increase the risk of CNS side effects such as restlessness and insomnia. Consult your doctor for advice on alcohol consumption while taking Rynazma 400 MG Tablet 10.

Liver

If you have liver issues, be cautious when starting Rynazma 400 MG Tablet 10. It is contraindicated in severe liver impairment. This medicine may affect liver function, so discussing your health status with your doctor is recommended.

Kidney

Rynazma 400 MG Tablet 10 should be used with caution if you have any kidney problems. Dosage adjustment may be required. Your doctor will guide you based on your health status.

Using Machines & Driving

Rynazma 400 MG Tablet 10may cause dizziness or tiredness which could affect your ability to drive or operate machinery. Be sure to know how you react to the medicine before engaging in such activities.

Allergy

Avoid using Rynazma 400 MG Tablet 10if you are allergic to doxofylline or any other xanthine derivatives. If you experience any allergic reactions, seek immediate medical help.

Children

Rynazma 400 MG Tablet 10 should be used in children only when prescribed by a child’s doctor. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Rynazma 400 MG Tablet 10under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Rynazma 400 MG Tablet 10interacts with the following medicines:

Antibiotics: Medicines like ciprofloxacin and erythromycin can increase levels of doxofylline in the blood, potentially escalating side effects.
Antidepressants: Fluvoxamine can interact with Duphill Tablet, leading to increased levels of doxofylline in your body, which might amplify side effects.
Antiarrhythmics: When taken alongside Duphill Tablet, mexiletine could elevate blood concentrations of doxofylline, increasing the risk of side effects.

Drug-Food Interactions

Rynazma 400 MG Tablet 10interacts with the following foods:

Caffeine: Consuming large amounts of caffeine or chocolate while taking Rynazma 400 MG Tablet 10can increase side effects like restlessness and insomnia.

Drug-Disease Interactions

Rynazma 400 MG Tablet 10interacts with the following diseases:

Peptic Ulcer Disease: If you have a history of peptic ulcers, using Rynazma 400 MG Tablet 10could worsen your condition due to its potential gastrointestinal side effects.
Seizure Disorders: This medicine might exacerbate seizure disorders as it has been associated with an increased risk of seizures in susceptible individuals.
Hypertension: This medication might further increase blood pressure due to its cardiovascular side effects.

Daily Dose

It's crucial that you take Rynazma 400 MG Tablet 10as prescribed by your doctor. The dosage can vary based on individual factors, such as how severe your condition is and how you respond to the medicine. Always follow the dosage prescribed and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Rynazma 400 MG Tablet 10, you may experience symptoms like nausea, vomiting, stomach pain, restlessness, tremor, rapid heartbeat, palpitations, dizziness and headache. Severe overdose may cause seizures, arrhythmias, hypotension and respiratory depression. Seek urgent medical attention if severe symptoms or collapse occur.

Missed Dose

In case you forget to take a dose of Duphill Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase your dose without consulting your doctor.

Store Rynazma 400 MG Tablet 10at a cool room temperature between 20°C to 25°C.
Keep it away from light, heat and moisture to maintain its efficacy.
Always ensure Rynazma 400 MG Tablet 10is stored out of reach from children and pets for safety.

If you're prescribed Rynazma 400 MG Tablet 10for asthma or COPD, try incorporating easy breathing exercises into your daily routine. This can help manage your respiratory condition by improving lung capacity.
Aim to avoid exposure to dust, smoke and other airborne allergens. These can trigger asthma attacks or worsen COPD symptoms. Regularly clean your living environment to minimise these triggers.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Asthma, COPD
Drug Category	Xanthine Derivative
Therapeutic Category	Bronchodilator

What is the primary use of Duphill Tablet?

Rynazma 400 MG Tablet 10is primarily used to manage respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD) by relaxing and widening the airways.

How does Rynazma 400 MG Tablet 10work in managing these conditions?

Rynazma 400 MG Tablet 10contains doxofylline, which inhibits an enzyme, leading to the relaxation of bronchial muscles and the dilation of airways, thereby reducing lung inflammation.

Can Rynazma 400 MG Tablet 10be used during an acute asthma attack?

No, Rynazma 400 MG Tablet 10is not meant for immediate relief during an acute asthma attack. It is designed for regular use to manage symptoms, not for emergency situations.

Should I take Rynazma 400 MG Tablet 10if I am pregnant or breastfeeding?

If you're pregnant or breastfeeding, consult your doctor before taking Duphill Tablet, as its safety in these situations is not established yet.

Can I take Rynazma 400 MG Tablet 10with other medicines?

Yes, but some medicines like antibiotics, antidepressants, or antiarrhythmics might interact with doxofylline in Duphill Tablet, increasing side effects. Always inform your doctor about all medicines you're currently taking.

What if I forget to take a dose of Duphill Tablet?

If you miss a dose, take it as soon as you remember. If it's close to your next dose time, skip the missed one and continue your normal schedule.

Can I stop taking Rynazma 400 MG Tablet 10once my symptoms improve?

No, discontinuing Rynazma 400 MG Tablet 10suddenly may worsen your symptoms. Always consult your doctor before stopping the medication, even if your symptoms have improved.

Last Updated On 13 May. 2025 | 11:17AM (IST)

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 6 years

MD Ayurveda

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

A-41 Industrial Area Phase VIII-A SAS Nagar PB 160071 IN ,

Country of origin: INDIA

Expiry on or after: January 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Doxofylline: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09273
PubChem. (n.d.). Doxofylline. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/50942
Matera, M. G., Page, C., & Cazzola, M. (2017). Doxofylline is not just another theophylline! International Journal of Chronic Obstructive Pulmonary Disease/International Journal of COPD, Volume 12, 3487–3493. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723117/
Chronic obstructive pulmonary disease (COPD): MedlinePlus Medical Encyclopedia. (n.d.). https://medlineplus.gov/ency/article/000091.htm
National Library of Medicine. (n.d.). Asthma. Asthma Symptoms | Asthma Attack | MedlinePlus. https://medlineplus.gov/asthma.html

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Telephone:09240250346

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