Diapar 10/500 MG Tablet 10

Navil Laboratories

Pack of 10 Units

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Old MRP ₹48.25

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Composition

Domperidone (10 Mg) + Paracetamol/acetaminophen (500 Mg)

Diapar 10/500 MG Tablet 10 is a prescription medication primarily used to manage migraine headaches. It's a combination medicine and belongs to the class of analgesics and antiemetics.

In addition to its main use, this medicine also helps manage associated symptoms of migraines, such as nausea and vomiting. By reducing the intensity of these symptoms, it allows you to carry out your daily activities more comfortably.

The medicine should be taken orally as directed by your doctor. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

Diapar 10/500 MG Tablet 10 is used for the following:

Management of acute migraine headaches in adults
Reduction of nausea and vomiting associated with migraines
Alleviation of stomach discomfort during migraines

Here's how to take Diapar 10/500 MG Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Make sure you don't exceed the recommended dose without consulting your doctor.
Never stop taking this medicine without first consulting your doctor.

Diapar 10/500 MG Tablet 10 is taken orally.

While taking Diapar 10/500 MG Tablet 10, you might experience the following side effects:

Dry mouth
Headache
Dizziness
Abdominal pain
Diarrhoea
Constipation
Extrapyramidal symptoms: These are movement disorders that can cause muscle stiffness, twitching, or restlessness.
Gynecomastia: This is a condition where men develop enlarged breast tissue.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Diapar 10/500 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dry Mouth: Try to stay well hydrated by drinking plenty of water throughout the day.
Abdominal Pain: Consider taking Diapar 10/500 MG Tablet 10 with light meals to help ease stomach discomfort.

Diapar 10/500 MG Tablet 10 works through the combined action of two active ingredients:

Domperidone (10 mg): This antiemetic and prokinetic agent works by blocking dopamine receptors in the chemoreceptor trigger zone and the gastrointestinal tract. This action helps reduce nausea and vomiting, which are common symptoms during a migraine.
Paracetamol (500 mg): This analgesic and antipyretic ingredient helps manage the pain of a migraine by inhibiting the synthesis of prostaglandins in the central nervous system. While paracetamol also has the ability to reduce fever, this effect is not the primary reason for its inclusion in Diapar 10/500 MG Tablet 10.

Pregnancy

Caution is advised while taking Diapar 10/500 MG Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you're breastfeeding, it's recommended to discuss with your doctor before using Diapar 10/500 MG Tablet 10.

Alcohol

Consuming alcohol while using Diapar 10/500 MG Tablet 10 might lead to increased side effects. It's better to avoid or limit alcohol consumption during this period.

Liver

If you have any liver problems, it's advisable to discuss with your doctor before starting Diapar 10/500 MG Tablet 10. This medicine may impact liver function.

Kidney

Caution is advised before using Diapar 10/500 MG Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Diapar 10/500 MG Tablet 10 might cause dizziness. If you experience this, avoid driving or operating heavy machinery until you feel well again.

Allergy

If you are aware of any allergies to domperidone or paracetamol, talk to your doctor before using Diapar 10/500 MG Tablet 10.

Children

Diapar 10/500 MG Tablet 10 is not recommended for children below the age of 12. Always consult your doctor before giving this medication to a child.

Older Patients

Older patients should take Diapar 10/500 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Diapar 10/500 MG Tablet 10 interacts with the following medicines:

Antiarrhythmics: Medicines like amiodarone or disopyramide may interact with Diapar 10/500 MG Tablet 10, potentially leading to a prolonged QT interval due to domperidone.
Antipsychotics: Medicines such as haloperidol or chlorpromazine may enhance the QT-prolonging effect of domperidone in Diapar 10/500 MG Tablet 10.
Antibiotics: Certain antibiotics like erythromycin or clarithromycin can increase domperidone levels, leading to an increased risk of side effects.
Anticoagulants: Paracetamol in Diapar 10/500 MG Tablet 10 can interact with warfarin, increasing the risk of bleeding.

Drug-Food Interactions

Diapar 10/500 MG Tablet 10 has no known specific food interactions.

Drug-Disease Interactions

Diapar 10/500 MG Tablet 10 interacts with the following diseases:

Hepatic Impairment: Severe liver disease can increase the risk of adverse effects from both paracetamol and domperidone in Diapar 10/500 MG Tablet 10.
Cardiovascular Disease: Diapar 10/500 MG Tablet 10 tablets should be used cautiously in patients with heart conditions due to potential QT prolongation caused by domperidone.
Gastrointestinal Disorders: People suffering from conditions like gastrointestinal haemorrhage, obstruction, or perforation should avoid taking Diapar 10/500 MG Tablet 10.
Prolactinoma: This condition can be exacerbated by domperidone in Diapar 10/500 MG Tablet 10.

Daily Dose

As per your doctor's instructions, take the prescribed dose of Diapar 10/500 MG Tablet 10. The dosage may vary based on your symptoms and response to the medicine.

Over Dose

If you accidentally take more than the recommended dose of Diapar 10/500 MG Tablet 10, you may experience dry mouth, dizziness, and upset stomach. Consult your doctor if these symptoms persist.

Missed Dose

If you forget to take your Diapar 10/500 MG Tablet 10 dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose. Always consult your doctor before adjusting your dosage.

Store your Diapar 10/500 MG Tablet 10 in a cool, dry place.
Keep it away from direct sunlight and moisture.
Always keep this medicine out of reach and sight of children.
Make sure to use Diapar 10/500 MG Tablet 10 before its expiry date.

To help manage migraines, actively seek to identify and avoid any specific food triggers. Common triggers can include chocolate, cheese, citrus fruits, or caffeine.
Regular physical activity can help reduce the frequency and severity of migraines. Aim for at least 150 minutes of moderate-intensity exercise each week. Remember to consult your doctor before starting any new exercise regimen.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Migraine headaches, Nausea, Pain
Drug Category	Antiemetic, Analgesic
Therapeutic Category	Migraine Management

What is Diapar 10/500 MG Tablet 10?

This medicine contains two active ingredients, domperidone and paracetamol, and is used to manage symptoms of migraine headaches in adults.

How does Diapar 10/500 MG Tablet 10 work?

Diapar 10/500 MG Tablet 10 works by blocking pain signals from reaching the brain (paracetamol) and reducing nausea and vomiting (domperidone), common symptoms of migraines.

Can I take Diapar 10/500 MG Tablet 10 for any other pains?

No, Diapar 10/500 MG Tablet 10 is specifically indicated for managing migraine headaches. For other types of pain, consult your doctor.

Can children below 12 years take Diapar 10/500 MG Tablet 10?

No, this medicine is not recommended for use in children under 12 years of age. Always consult your doctor for appropriate medication.

Are there any precautionary measures while taking Diapar 10/500 MG Tablet 10?

Yes, patients with moderate liver impairment or severe kidney impairment should use this medicine cautiously and under medical supervision.

What are the possible side effects of Diapar 10/500 MG Tablet 10?

Common side effects include dry mouth, headache, dizziness, and stomach upset. If you experience severe or persistent side effects, seek medical attention immediately.

What happens if I overdose on Diapar 10/500 MG Tablet 10?

Overdose can cause severe symptoms like extreme discomfort in the stomach (domperidone overdose) or potential liver damage (paracetamol overdose). Seek immediate medical help.

Last Updated On 13 May. 2025 | 11:17AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 9 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Krishna Kunj, S V Road, Malad West, Malad West, Mumbai, Maharashtra 400064

Country of origin: INDIA

Expiry on or after: July 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Food and Drug Administration. (2021). Domperidone IND packet (pp. 1–5). https://www.fda.gov/media/100064/download
Domperidone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01184
Sharma, S., Chandel, D., Sudan, P., Jain, K. U., & Chandigarh College of Pharmacy. (2017). SHORT REVIEW ON DOMPERIDONE TABLET [Journal-article]. Journal of Applied Pharmaceutical Research, 14–19. https://media.neliti.com/media/publications/320070-short-review-on-domperidone-tablet-0768124d.pdf
Crocin. (n.d.). Crocin® Advance (pp. 1–3). https://www.crocin.com/content/dam/cf-consumer-healthcare/panadol/en_in/adult/productshots/pdfs/Crocin-advance-Product-Info.pdf
DailyMed - TYLENOL REGULAR STRENGTH- acetaminophen tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1622f694-4d63-4c56-8737-fae31f0ecfb7
Acetaminophen: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00316

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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