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Orange Juice: Uses, Benefits and Side Effects

Last updated on : 09 Jul, 2025

Read time : 11 min

Orange juice is more than just a breakfast drink, but a refreshing beverage packed with immune-boosting vitamin C, heart-healthy antioxidants, and essential nutrients. In this blog, discover the nutritional value, science-backed health benefits, skincare uses, and potential side effects of orange juice to help you make informed dietary choices.

Orange Juice Nutrition Facts (Per 100g)

Orange juice is a powerhouse of essential nutrients, offering a wide array of vitamins, minerals, and antioxidants in every sip. The table below provides an overview of the key nutrients:

NutrientAmount per 100 g
Vitamin C53.2 mg (93% DV)
Folate (Vitamin B9)39.5 mcg (10% DV)
Potassium181 mg (5% DV)
Magnesium11 mg (3% DV)
Protein0.7 g
Fibre0.2 g
Sugar8.6 g
CarotenoidsVarious amounts
HesperidinSignificant amounts

Medicinal Properties of Orange Juice

Orange juice boasts several remarkable properties that contribute to its overall health benefits:

  • Immune Support: The high vitamin C content in orange juice enhances the production and function of white blood cells, while also acting as an antioxidant to protect immune cells.
  • Anti-Inflammatory Effects: Orange juice is rich in antioxidants, including vitamin C, hesperidin, and other flavonoids, which help reduce inflammation markers in the body.
  • Cardiovascular Health: The potassium and hesperidin found in orange juice can help lower LDL cholesterol and increase HDL cholesterol levels, thus supporting heart health.
  • Kidney Stone Prevention: The citrate content in orange juice helps prevent kidney stones by binding with calcium before it can form stones.

Top 6 Health Benefits of Orange Juice

Orange juice is a nutritional powerhouse, packed with essential vitamins, minerals, and antioxidants that support overall health and well-being. Let us explore some of the specific benefits that orange juice offers for the brain, heart, and weight management.

1) Potential Benefits of Orange Juice for the Brain

The nutrients and plant compounds found in orange juice may have a positive impact on brain function and cognitive health. The flavonoids present in orange juice, particularly hesperidin, possess antioxidant and anti-inflammatory properties that help shield the brain from oxidative stress and inflammation, which are linked to cognitive decline. 

Furthermore, the vitamin C and other essential nutrients in orange juice support the health of neurons and overall brain function, potentially aiding in the prevention of age-related cognitive disorders such as Alzheimer’s disease and dementia.

2) Potential Benefits of Orange Juice for the Heart

In addition to its brain-boosting properties, orange juice may also contribute to a healthier heart by targeting several risk factors associated with cardiovascular disease. The high potassium content in orange juice helps regulate blood pressure, while the antioxidants, such as hesperidin, protect against the oxidation of cholesterol, a significant risk factor for atherosclerosis. 

Studies have demonstrated that regular consumption of orange juice over an extended period can lead to lower levels of total and ‘bad’ LDL cholesterol, increased levels of ‘good’ HDL cholesterol, and decreased diastolic blood pressure.

3) Potential Benefits of Orange Juice for Obesity

While orange juice is relatively high in calories and natural sugars, it can still be enjoyed as part of a balanced diet for those looking to manage their weight. The soluble fibre and antioxidants present in orange juice can help reduce cholesterol and blood sugar levels, which are essential factors in maintaining a healthy weight.

However, it is crucial to consume orange juice in moderation owing to its calorie content. Opting for 100% orange juice without added sugars and limiting your daily intake can allow you to reap the nutritional benefits of this beverage without compromising your weight management goals.

4) Potential Benefits of Orange Juice for Cancer

The high antioxidant content in orange juice, particularly flavonoids like hesperidin and carotenoids, may help protect the body’s cells from damage caused by free radicals. This, in turn, could potentially reduce the risk of certain types of cancer.

These antioxidants can improve blood vessel function, which may be beneficial in preventing cardiovascular-related cancers. Moreover, the vitamin C in orange juice supports the immune system, further aiding in the fight against diseases, including potentially reducing the risk of cancer. While these potential benefits are promising, it’s essential to note that further research is needed to fully understand the role of orange juice in cancer prevention.

5) Potential Benefits of Orange Juice for Microbial Infections

The high vitamin C content in orange juice plays a crucial role in boosting the immune system and combating microbial infections. Vitamin C is essential for the production of white blood cells, which are the body’s primary defence against infections.

Consuming orange juice regularly may help prevent respiratory illnesses such as the common cold and flu by enhancing the immune response. Additionally, the antioxidants present in orange juice can help reduce inflammation and oxidative stress, further aiding in the recovery from microbial infections.

6) Potential Benefits of Orange Juice for Metabolic Diseases

Orange juice can be beneficial for metabolic health due to its soluble fibre content, particularly when consumed with pulp. This fibre can help lower cholesterol and blood sugar levels, reducing the risk of metabolic diseases such as diabetes and heart disease.

The potassium found in orange juice also plays a crucial role in regulating fluid balance and blood pressure, which is essential for managing conditions such as hypertension and metabolic syndrome. However, since oranges are high in sugar, people with diabetes must always consult their doctor before consuming them.

How to Include Orange Juice in Your Diet?

To use orange juice healthily, opt for 100% pure orange juice that contains no added sugars.

  • You can enjoy it freshly squeezed or diluted with water to reduce the calorie content.
  • Orange juice makes a great breakfast beverage, but it can also be used as a marinade for grilled chicken or as a base for salad dressings.

While orange juice is a delicious and nutritious beverage, it is important to be aware of potential side effects.

Is Orange Juice Good for Skin? How to Use It Topically

Using orange juice on the face can provide numerous skin benefits due to its vitamin C content. To apply:

  • Cleanse your face thoroughly.
  • Dilute fresh orange juice with an equal part of water to avoid irritation.
  • Using a cotton ball, gently dab the mixture onto your skin, focusing on areas prone to dullness or pigmentation.
  • Leave it on for 10-15 minutes before rinsing off with lukewarm water.

This can help brighten the complexion, reduce dark spots, and provide a natural glow. However, avoid sun exposure immediately after application, as orange juice may increase skin sensitivity to UV rays.

Side Effects of Drinking Too Much Orange Juice

Consuming excessive amounts of orange juice can lead to several adverse effects:

  • The high sugar content may contribute to weight gain and increase the risk of developing type 2 diabetes.
  • The acidity of orange juice can erode tooth enamel, leading to dental problems.
  • Excessive fibre intake from orange juice can cause digestive issues such as abdominal cramps, diarrhoea, and bloating.
  • Some individuals may experience severe heartburn, nausea, vomiting, headaches, and insomnia.
  • In rare cases, consuming orange juice may trigger skin allergies and sleep disturbances due to sudden spikes in blood sugar levels.

Precautions While Drinking Orange Juice

When incorporating orange juice into your diet, keep the following precautions in mind:

  • Pregnant and breastfeeding women should limit their intake to normal food amounts, as there is insufficient evidence regarding safety in larger quantities.
  • Be cautious when taking medications like celiprolol, ivermectin, and quinolone antibiotics, as orange juice can interfere with their absorption.
  • To protect your dental health, drink orange juice with meals, use a straw to minimise contact with teeth, and rinse your mouth with water afterwards.
  • Limit your daily consumption to the recommended amount (approximately 240 ml) to avoid excessive sugar and calorie intake.

Takeaway

Orange juice can be a delicious and nutrient-rich addition to your diet when consumed in moderation. From supporting brain and heart health to boosting immunity and aiding digestion, its benefits are diverse. However, its high sugar and acidity mean it’s best enjoyed as part of a balanced diet. Choose 100% pure juice, limit daily intake, and pair it with meals to maximise benefits while protecting your health.

Expert Quote

“Orange juice is an excellent source of vitamin C and antioxidants, but portion control is key due to its natural sugar content.”

-Dr Anubha Karol

Frequently Asked Questions (FAQ)

Is drinking orange juice good for you?

Drinking orange juice can be beneficial owing to its high content of vitamin C, folate, and antioxidants, which support immune function and heart health and reduce the risk of certain diseases

Is orange juice good for your stomach?

Orange juice, especially with pulp, can be good for digestive health due to its fibre content, which helps maintain a healthy digestive system and reduces cholesterol and blood sugar levels.

What is the healthiest orange juice to drink?

The healthiest option is 100% orange juice with extra pulp, as it contains more fibre and beneficial plant compounds like flavonoids without added sugars.

Are there orange juice benefits for skin?

Yes, orange juice is beneficial for skin health due to its high content of vitamin C, which is essential for collagen production and maintaining healthy skin.

Is orange juice healthy for weight loss?

Although orange juice contains a higher amount of calories and natural sugars, it can still be included in a balanced diet for individuals aiming to manage their weight.

Is orange juice high in sugar?

Yes, orange juice is high in sugar, with one cup containing about 21 grams of sugar, which can increase blood sugar levels and is a concern for those managing blood sugar.

Do oranges make skin glow?

Oranges, and by extension orange juice, can contribute to glowing skin due to their high vitamin C content, which supports collagen production and overall skin health.

Which juice is best for a glowing face?

Orange juice is good for face glow due to its rich content of vitamin C and antioxidants, which help in maintaining healthy and glowing skin.

References

  • Cara, K. C., Beauchesne, A. R., Wallace, T. C., & Chung, M. (2021). Effects of 100% orange juice on markers of inflammation and oxidation in Healthy and At-Risk adult populations: A scoping review, systematic review, and meta-analysis. Advances in Nutrition, 13(1), 116–137. https://doi.org/10.1093/advances/nmab101
  • Ruxton, C. H. S., & Myers, M. (2021). Fruit juices: Are they helpful or harmful? An evidence review. Nutrients, 13(6), 1815. https://doi.org/10.3390/nu13061815
  • Robayo, S., Kucab, M., Walker, S. E., Suitor, K., D’Aversa, K., Morello, O., & Bellissimo, N. (2024). Effect of 100% orange juice and a Volume-Matched Sugar-Sweetened drink on subjective appetite, food intake, and glycemic response in adults. Nutrients, 16(2), 242. https://doi.org/10.3390/nu16020242
  • Yun, J., Mullarky, E., Lu, C., Bosch, K. N., Kavalier, A., Rivera, K., Roper, J., Chio, I. I. C., Giannopoulou, E. G., Rago, C., Muley, A., Asara, J. M., Paik, J., Elemento, O., Chen, Z., Pappin, D. J., Dow, L. E., Papadopoulos, N., Gross, S. S., & Cantley, L. C. (2015). Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science, 350(6266), 1391–1396. https://doi.org/10.1126/science.aaa5004
  • Beckett, E. L., Fayet-Moore, F., Cassettari, T., Starck, C., Wright, J., & Blumfield, M. (2024). Health effects of drinking 100% juice: an umbrella review of systematic reviews with meta-analyses. Nutrition Reviews. https://doi.org/10.1093/nutrit/nuae036
  • Khan, A., Ikram, M., Hahm, J. R., & Kim, M. O. (2020). Antioxidant and Anti-Inflammatory Effects of Citrus flavonoid hesperetin: Special focus on neurological disorders. Antioxidants, 9(7), 609. https://doi.org/10.3390/antiox9070609
  • Aptekmann, N. P., & Cesar, T. B. (2013). Long-term orange juice consumption is associated with low LDL-cholesterol and apolipoprotein B in normal and moderately hypercholesterolemic subjects. Lipids in Health and Disease, 12(1). https://doi.org/10.1186/1476-511x-12-119
  • Miles, E. A., & Calder, P. C. (2021). Effects of citrus fruit juices and their bioactive components on inflammation and immunity: a narrative review. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.712608
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