Trisopt Ophthalmic Suspension 5ml

Micro Labs Ltd

Bottle of 5 ML

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Old MRP ₹536

MRP ~~₹502.5~~

₹427.12

₹100.5/ML

15% off

*MRP inclusive of all taxes

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15 days Easy returns

Prescription required for this medicine

Store Below 30^o C

Composition

Benzalkonium Chloride (0.2 Mg) + Brimonidine (2 Mg) + Brinzolamide (10 Mg) + Timolol (5 Mg)

Trisopt Ophthalmic Suspension 5ml are used to reduce high intraocular pressure in individuals with open-angle glaucoma or ocular hypertension. It is a combination medicine that belongs to the groups of alpha-2 adrenergic receptor agonists, non-selective beta-adrenergic receptor blocking agents, and carbonic anhydrase inhibitors.

This medicine also helps in preserving vision by preventing optic nerve damage.

Always instil these drops as directed by your doctor. Before starting this, inform your doctor of any pre-existing conditions or ongoing medications. If you notice any side effects while using these eye drops, notify your doctor immediately. It is crucial to continue using the eye drops for the duration prescribed by your doctor to achieve the best results.

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Trisopt Ophthalmic Suspension 5ml are used for the following:

Management of open-angle glaucoma: This is a condition where the fluid in the eye does not drain properly, leading to a gradual loss of sight.
Control of ocular hypertension: This means high pressure inside the eyes that can damage the optic nerve and lead to vision loss.

Use Trisopt Ophthalmic Suspension 5ml as follows:

Shake the bottle well before use.
Tilt your head back slightly and pull down your lower eyelid to create a small pocket.
Hold the dropper above your eye and squeeze out one drop.
Close your eye gently and press your finger to the inside corner of your eye for about 1 minute to prevent the liquid from draining into your tear duct.
If you need to use another drop or a different type of eye medication, wait for at least 5 minutes before putting it.
Always remember to consult with your doctor for more specific instructions.

Trisopt Ophthalmic Suspension 5ml are instilled topically.

Trisopt Ophthalmic Suspension 5ml may cause the following common side effects:

Blurred vision
Eye irritation
Stinging Sensation
Redness
Dry eye
Unusual taste
Dry mouth

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Trisopt Ophthalmic Suspension 5ml. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Unusual taste: This is temporary and can be reduced by gently pressing the inner corner of the eye for one minute after use.

Trisopt Ophthalmic Suspension 5ml contains the following components:

Brimonidine (2 mg): As an alpha-2 adrenergic receptor agonist, brimonidine reduces IOP by decreasing aqueous humour production and increasing uveoscleral outflow. This dual mechanism makes it an efficient ocular hypotensive agent.
Brinzolamide (10 mg): Brinzolamide is a carbonic anhydrase inhibitor that reduces IOP by decreasing aqueous humour secretion. It works by selectively inhibiting the carbonic anhydrase II enzyme in the ciliary epithelium, which ultimately reduces bicarbonate ion formation and aqueous humour production.
Timolol (5 mg): It is a non-selective beta-adrenergic receptor blocking agent. It decreases aqueous humour production, thereby reducing IOP.
Benzalkonium Chloride (0.2 mg): It acts as an antimicrobial preservative in the eye drops. It prevents microbial growth and contamination in the multi-dose container, ensuring the sterility of the solution.

Pregnancy

Caution is advised while using Trisopt Ophthalmic Suspension 5ml if you are pregnant. It is recommended to consult your doctor before using this medicine.

Breastfeeding

Caution is advised while using Trisopt Ophthalmic Suspension 5ml during breastfeeding. Timolol may pass into the breast milk. Inform your doctor before these drops are prescribed to you.

Alcohol

Interactions between Trisopt Ophthalmic Suspension 5ml and alcohol are highly unlikely as these are topical eye drops.

Liver

Caution is advised while using Trisopt Ophthalmic Suspension 5ml if you have any liver issues. Make sure to discuss your liver health with your doctor before starting this medicine.

Kidney

Those with kidney health concerns should exercise caution when using Trisopt Ophthalmic Suspension 5ml. Please consult your doctor for guidance.

Using Machines & Driving

Trisopt Ophthalmic Suspension 5ml may cause blurred vision which could affect the ability to drive or operate machinery. Be cautious and ensure clarity of vision before doing such activities.

Allergy

Trisopt Ophthalmic Suspension 5ml are contraindicated in individuals with known hypersensitivity to any of its components. If you have any known allergies, discuss them with your doctor before starting this medication.

Children

The safety and effectiveness of Trisopt Ophthalmic Suspension 5ml in children have not been established. Always consult your doctor before giving any medicine to a child.

Older Patients

No significant differences have been observed between elderly and younger adult patients using Trisopt Ophthalmic Suspension 5ml. However, older patients may be more susceptible to side effects or have liver and kidney issues. It is advisable that older patients use this medicine under medical supervision.

Drug-Drug Interactions

Trisopt Ophthalmic Suspension 5ml interacts with the following medicines:

Oral Carbonic Anhydrase Inhibitors: Medicines such as acetazolamide may interact with Trisopt Ophthalmic Suspension 5ml, potentially increasing the risk of systemic carbonic anhydrase inhibition and acid–base or electrolyte disturbances.
High-dose Salicylate Therapy: Large doses of salicylates may interact with the carbonic anhydrase inhibitor component of Trisopt Ophthalmic Suspension 5ml, increasing the risk of metabolic acidosis and salicylate toxicity.
CNS Depressants: Medicines such as diazepam or alprazolam may enhance the central nervous system effects of the brimonidine component in Trisopt Ophthalmic Suspension 5ml, possibly leading to increased drowsiness or sedation.
Antihypertensives/Cardiac Glycosides: Concomitant use with antihypertensives or cardiac glycosides such as digoxin may potentiate hypotension or bradycardia due to additive cardiovascular effects.
Tricyclic Antidepressants: Medicines such as amitriptyline may interfere with the intraocular pressure-lowering effect of brimonidine in Trisopt Ophthalmic Suspension 5ml, potentially reducing its efficacy.
Monoamine Oxidase Inhibitors: MAO inhibitors may increase systemic effects of brimonidine in Trisopt Ophthalmic Suspension 5ml, potentially leading to enhanced hypotensive responses or central adverse effects.

Drug-Food Interactions

There are no known food interactions with Trisopt Ophthalmic Suspension 5ml.

Drug-Disease Interactions

Trisopt Ophthalmic Suspension 5ml interacts with the following diseases:

Cardiovascular Disease: Patients with cardiovascular disease might experience increased hypotension after using these drops.
Raynaud's Phenomenon: Trisopt Ophthalmic Suspension 5ml should be used with caution in patients with Raynaud's phenomenon, as it may worsen peripheral vasospasm and reduce blood flow to the extremities.
Orthostatic Hypotension: Trisopt Ophthalmic Suspension 5ml may increase the risk of symptomatic blood pressure drops on standing, particularly in patients predisposed to orthostatic hypotension.
Thromboangiitis Obliterans: Caution is advised when using Trisopt Ophthalmic Suspension 5ml in patients with thromboangiitis obliterans, as it may aggravate peripheral circulatory impairment.
Diabetes: Timolol can mask the symptoms of hypoglycaemia, such as rapid heartbeat, making it harder to recognise low blood sugar levels. Diabetic patients should monitor their blood glucose levels closely.
Myasthenia Gravis: Timolol may exacerbate muscle weakness in patients with myasthenia gravis, leading to increased symptoms. Close monitoring and consultation with a healthcare provider are essential.

Daily Dose

The daily dose of Trisopt Ophthalmic Suspension 5ml should be used as suggested by your doctor, considering factors like the severity of your condition and how you respond to this medication. Always adhere to the prescribed dosage, and never modify it without your doctor's advice.

Over Dose

If you accidentally use more Trisopt Ophthalmic Suspension 5ml than recommended, don't panic. Rinse your eyes with clean water at room temperature. If you notice persistent or worsening symptoms, inform your doctor.

Missed Dose

If you miss a dose of Trisopt Ophthalmic Suspension 5ml, put it on as soon as you remember. If it is nearly time for the next dose, skip the missed dose and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store Trisopt Ophthalmic Suspension 5ml below 25°C.
Keep them away from excessive heat and light, and don't freeze them.
Discard any remaining portion 28 days after opening the bottle.

Avoid touching or rubbing your eyes after applying the drops.
Remove contact lenses before use and wait at least 15 minutes before reinserting them.
If using for glaucoma, maintain a balanced diet rich in leafy greens and omega-3 fatty acids to support eye health.
Limit caffeine and excessive salt intake to avoid fluid retention that can impact eye pressure.
Use sunglasses to protect your eyes from UV rays and irritation.
Regularly monitor your eye pressure and follow up with your doctor as advised.

Fact Box

Available Dosage Types	Eye drops
Habit Forming	No
Ailment	Open-Angle Glaucoma, Ocular Hypertension
Drug Category	Alpha-2 Adrenergic Agonist, Non-selective Beta-adrenergic Receptor Blocker, Carbonic Anhydrase Inhibitor
Therapeutic Category	Antiglaucoma agent

What are Trisopt Ophthalmic Suspension 5ml used for?

These drops are used to manage open-angle glaucoma and ocular hypertension by reducing the pressure inside the eye.

How do Trisopt Ophthalmic Suspension 5ml work?

They contain brimonidine, brinzolamide and timolol, which decrease aqueous humour production in the eye, thereby reducing eye pressure.

Can Trisopt Ophthalmic Suspension 5ml cause any side effects?

Yes, they can cause blurred vision, stinging sensation, unusual taste, eye irritation, and dry mouth.

Can I use contact lenses while using Trisopt Ophthalmic Suspension 5ml?

You should remove lenses before using the drops and wait at least 15 minutes before reinserting them.

Are there any precautions I should take when using Trisopt Ophthalmic Suspension 5ml?

Use with caution if you have diabetes, myasthenia gravis, cardiovascular disease, raynaud's phenomenon, orthostatic hypotension, and thromboangiitis obliterans.

Can pregnant or nursing women use Trisopt Ophthalmic Suspension 5ml?

These drops are not recommended during pregnancy or lactation. Always consult your doctor first.

Last Updated On 25 Feb. 2026 | 7:22PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead & Reviewer | 7 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 12 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

CTS No. 73, Saki Estate Off, Chandivali Road, Chandivali, Andheri East, Mumbai, Maharashtra 400072

Country of origin: INDIA

Expiry on or after: July 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

SIMBRINZA™ (brinzolamide/brimonidine tartrate ophthalmic suspension. (n.d.). Fda.Gov. Retrieved February 18, 2026, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204251s000lbl.pdf
Benzalkonium: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-e). DrugBank. https://go.drugbank.com/drugs/DB11105
Timolol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00373
Brimonidine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00484
Brinzolamide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-b). DrugBank. https://go.drugbank.com/drugs/DB01194

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Registered Office Address

Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

Grievance Officer

Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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