SANDOSTATIN LAR 20MG INJECTION 1ML is used in adults for the long-term treatment of certain hormone-related disorders and tumour-related symptoms. It belongs to the class of medicines known as somatostatin analogues.
It is used for conditions such as acromegaly (excess growth hormone), severe diarrhoea and flushing episodes associated with metastatic carcinoid tumours, and profuse watery diarrhoea due to vasoactive intestinal peptide (VIP) secreting tumours. By controlling these symptoms, it improves quality of life and reduces complications associated with hormone-secreting tumours.
Before starting treatment, your doctor will decide the dose and duration based on your clinical condition, tolerance to previous therapies, and your liver and kidney health. If you notice unusual side effects or changes during therapy, you should seek immediate medical advice.
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Sandostatin Lar 20Mg Injection 1Ml
Vial of 1 ML
Old MRP ₹41430
MRP ₹38840.62
₹31072.5
₹38840.62/ML
100% genuine medicines
Safe & secure payments
Safe packing and storage
Non returnable productView policy
Prescription required for this medicine
Store in refrigerator or (2° - 8° C) Do Not Freeze
CompositionAbout Sandostatin Lar 20Mg Injection 1Ml
Uses of Sandostatin Lar 20Mg Injection 1Ml
SANDOSTATIN LAR 20MG INJECTION 1ML is used for:
- Long-term management of acromegaly in patients who have responded to subcutaneous octreotide.
- Treatment of severe diarrhoea and flushing associated with metastatic carcinoid tumours.
- Management of profuse watery diarrhoea due to VIP-secreting tumours (VIPomas).
Directions for Use of Sandostatin Lar 20Mg Injection 1Ml
SANDOSTATIN LAR 20MG INJECTION 1ML is administered by deep intramuscular injection into the gluteal muscle. It should only be given by a healthcare professional.
Route of Administration
SANDOSTATIN LAR 20MG INJECTION 1ML is for intramuscular use only.
Side Effects of Sandostatin Lar 20Mg Injection 1Ml
Common side effects of SANDOSTATIN LAR 20MG INJECTION 1ML include:
- Diarrhoea
- Abdominal pain
- Flatulence
- Nausea and vomiting
- Headache and dizziness
- Cholelithiasis (gallstones)
- Back pain and fatigue
- Pain or swelling at the injection site
Management Of Side Effects:
Most side effects are temporary and resolve with continued treatment. If they persist or worsen, consult your doctor.
- Diarrhoea/nausea: Administer injections with meals or follow dietary guidance given by your doctor. Maintain hydration.
- Injection site pain: Rotate the injection site to minimise discomfort.
- Blood sugar changes: Monitor blood glucose regularly, especially if you have diabetes, as both hypo- and hyperglycaemia may occur.
How Sandostatin Lar 20Mg Injection 1Ml Works?
SANDOSTATIN LAR 20MG INJECTION 1ML contains the following active component:
- Octreotide (20 mg): Octreotide is a synthetic analogue of somatostatin. It works by binding to somatostatin receptors in various tissues, thereby suppressing the excessive release of hormones such as growth hormone, serotonin, insulin, glucagon, and vasoactive intestinal peptides. This leads to control of hormone-related symptoms and tumour-secretory activity.
Safety Measures & Warnings
Pregnancy
SANDOSTATIN LAR 20MG INJECTION 1ML should only be used in pregnancy if the potential benefit outweighs the risk to the unborn baby. Consult your doctor if you are pregnant or planning pregnancy.
Breastfeeding
Octreotide may pass into breast milk in small amounts. Use is not recommended during breastfeeding unless clearly advised by your doctor.
Alcohol
Alcohol does not directly interact with SANDOSTATIN LAR 20MG INJECTION 1ML. However, excessive alcohol can worsen liver function and alter metabolism, potentially aggravating side effects. Avoid or limit alcohol use.
Liver
Patients with liver cirrhosis may require dose adjustments and close monitoring, as liver metabolism affects the clearance of octreotide.
Kidney
Patients with kidney impairment may require careful monitoring and possible dose changes, as clearance of the medicine may be reduced.
Use In Driving And Operating Machinery
SANDOSTATIN LAR 20MG INJECTION 1ML may cause dizziness, tiredness, or visual changes in some patients. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Allergy
Do not use SANDOSTATIN LAR 20MG INJECTION 1ML if you are allergic to octreotide or any component of the formulation. Severe allergic reactions such as rash, itching, swelling, or breathing difficulty require immediate medical attention.
Children
SANDOSTATIN LAR 20MG INJECTION 1ML is not recommended in children and adolescents below 18 years of age due to lack of safety data.
Older Patients
Older patients generally tolerate SANDOSTATIN LAR 20MG INJECTION 1ML well, though they may require closer monitoring of blood glucose and gallbladder health.
Interactions of Sandostatin Lar 20Mg Injection 1Ml
Drug-Drug Interactions
SANDOSTATIN LAR 20MG INJECTION 1ML may interact with the following medicines:
- Antidiabetic agents (e.g., insulin, sulfonylureas): Risk of both hypoglycaemia and hyperglycaemia; glucose monitoring and dose adjustment may be necessary.
- Immunosuppressants (e.g., cyclosporine): May reduce cyclosporine absorption and effectiveness; monitoring of medicine levels is required.
- Beta-blockers and calcium channel blockers (e.g., atenolol, verapamil): May increase the risk of bradycardia and conduction abnormalities; cardiac monitoring is advised.
- Dopamine agonists (e.g., bromocriptine): Concomitant use may alter hormone control and requires careful dose regulation.
Drug-Disease Interactions
SANDOSTATIN LAR 20MG INJECTION 1ML may interact with the following conditions:
- Cholelithiasis (gallstones): Risk is increased with long-term therapy; routine ultrasound monitoring is recommended.
- Glucose metabolism disorders: May cause hypo- or hyperglycaemia; regular monitoring of blood sugar is required.
- Thyroid dysfunction: May reduce thyroid hormone levels, leading to hypothyroidism; thyroid function tests should be monitored periodically.
- Cardiac disorders (e.g., bradycardia, arrhythmias): Octreotide may worsen pre-existing cardiac conditions; patients require careful monitoring.
Dosage of Sandostatin Lar 20Mg Injection 1Ml
Daily Dose
The exact dose and interval of SANDOSTATIN LAR 20MG INJECTION 1ML will be decided by your doctor depending on your underlying condition and response to treatment. Dose adjustments may be required in patients with liver or kidney impairment.
Over Dose
An overdose is highly unlikely for this medication as it is administered by a healthcare professional.
Missed Dose
If you miss an injection appointment, contact your doctor or healthcare provider promptly to reschedule. Do not take a double dose to make up for the missed injection.
Storage
- Store at 2–8°C (refrigerator temperature).
- Do not freeze.
- Keep the vial in its original packaging to protect it from light.
- Keep out of reach and sight of children.
- Do not use after the expiry date printed on the label.
Special Dietary And Lifestyle Recommendation
- Maintain a balanced diet with limited intake of refined sugars to manage fluctuations in blood glucose.
- Ensure adequate hydration to counteract diarrhoea-related fluid loss.
- Regular ultrasound monitoring of gallbladder health is advisable due to risk of gallstone formation.
- Follow-up visits with your doctor for blood glucose and thyroid monitoring are strongly recommended.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Acromegaly, carcinoid tumours, VIP-secreting tumours |
| Drug Category | Somatostatin analogue |
| Therapeutic Category | Hormone-related and tumour-symptom control medicine |
Frequently Asked Questions (FAQs)
What is SANDOSTATIN LAR 20MG INJECTION 1ML used for?
Can SANDOSTATIN LAR 20MG INJECTION 1ML be used in children?
Does SANDOSTATIN LAR 20MG INJECTION 1ML cure acromegaly or tumours?
Can I take SANDOSTATIN LAR 20MG INJECTION 1ML if I have diabetes?
Does SANDOSTATIN LAR 20MG INJECTION 1ML affect driving?
Can SANDOSTATIN LAR 20MG INJECTION 1ML be used during pregnancy?
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Manufacturer details
Country of origin: AUSTRIA
References
- SANDOSTATIN LAR DEPOT. (n.d.). This label may not be the latest approved by FDA. For current labeling information, please visit https://www.fda.gov/drugsatfda. Fda.Gov. Retrieved September 18, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021008s043lbl.pdf
- Octreotide oral/injection Uses, Side Effects & Warnings. (n.d.). Drugs.Com. Retrieved September 18, 2025, from https://www.drugs.com/mtm/octreotide-oral-injection.html
- Octreotide . (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00104
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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