Gemtide 250 mcg Cartridge Injection 3 ml is used to manage postmenopausal osteoporosis. It is a single-ingredient parathyroid hormone analogue medicine containing teriparatide.
This medicine helps increase bone density and reduce fracture risk in women after menopause. It is also used in men with primary or hypogonadal osteoporosis at high fracture risk. It also helps manage bone loss caused by long-term steroid use.
Before starting, tell your doctor about your medical conditions and allergies. Tell the doctor about all other medicines, supplements or herbal products you take. Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding. Report persistent or serious side effects to your doctor. Do not stop taking or using the medicine unless your doctor advises you to do so.
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Gemtide 250 Mcg Cartridge Injection 3 Ml
Cartridge of 3 ML
Old MRP ₹9999
MRP ₹9374.06
₹7499.25
₹3124.69/ML
100% genuine medicines
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15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Gemtide 250 Mcg Cartridge Injection 3 Ml
Uses of Gemtide 250 Mcg Cartridge Injection 3 Ml
Gemtide 250 mcg Cartridge Injection 3 ml is used to manage osteoporosis and help strengthen bones in people at increased risk of fractures.
Uses of Gemtide 250 mcg Cartridge Injection 3 ml are:
- Postmenopausal Osteoporosis: Helps increase bone density and reduce the risk of fractures in women after menopause.
- Male Osteoporosis: Used in men with primary or hypogonadal osteoporosis who have a high risk of fractures.
- Glucocorticoid-Induced Osteoporosis: Helps manage bone loss associated with long-term glucocorticoid (steroid) treatment.
Directions for Use of Gemtide 250 Mcg Cartridge Injection 3 Ml
- A healthcare professional usually gives this medicine. It is administered via a subcutaneous route.
- Be aware that this medicine is for injection only. Do not attempt to swallow or apply it topically.
- Always consult your doctor for specific advice on how to use this medication.
Route of Administration
Gemtide 250 MCG Cartridge Injection is administered through the subcutaneous route, which involves injecting it under the skin.
Side Effects of Gemtide 250 Mcg Cartridge Injection 3 Ml
Gemtide 250 mcg Cartridge Injection 3 ml may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Gemtide 250 mcg Cartridge Injection 3 ml:
- Nervous System: Dizziness and headache.
- Digestive: Nausea.
- Musculoskeletal: Leg cramps and joint pain.
If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so.
Management Of Side Effects:
Most side effects of Teriparatide are temporary and generally harmless and resolve upon discontinuation of this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- If you experience injection site reactions such as redness or swelling, try to rotate the injection sites as directed by your doctor to avoid repeated trauma to the same area.
- In case of nausea or vomiting, take this medicine with food, as it can help to reduce these symptoms.
- Increasing fluid intake may help reduce constipation caused by this medication
How Gemtide 250 Mcg Cartridge Injection 3 Ml Works?
Gemtide 250 MCG Cartridge Injection contains the following components:
- Teriparatide (0.25 mg): Teriparatide is a parathyroid hormone analogue. It works by stimulating the formation of new bone, thereby increasing overall bone mass. This is achieved by the action of Teriparatide on the cells that are responsible for creating new bone. This helps in the strengthening weak and thin bones, reducing the risk of fractures.
Safety Measures & Warnings
Pregnancy
This medicine should not be used during pregnancy unless your doctor advises.
Breastfeeding
This medicine should not be used by breastfeeding mothers. Consult your doctor before using it if you are nursing.
Alcohol
Consult your doctor regarding alcohol consumption during treatment with Gemtide 250 MCG Cartridge Injection, as it may interfere with the medication's efficacy or increase side effects.
Liver
If you have liver health issues, it is advised to consult your doctor before using Gemtide 250 MCG Cartridge Injection. Your doctor can assess if this medicine is suitable for you, considering your health status.
Kidney
Caution is advised while taking this injection if you have kidney problems. If you have kidney-related health issues, inform your doctor before using Gemtide 250 MCG Cartridge Injection. They will evaluate your condition to determine if the medication is safe.
Use In Driving And Operating Machinery
Gemtide 250 MCG Cartridge Injection may cause dizziness. This could affect your ability to drive or operate machinery. If you experience dizziness after taking this medicine, avoid driving or operating heavy machinery.
Allergy
If you are allergic to teriparatide or any other components of Gemtide 250 MCG Cartridge Injection, avoid this medicine. Inform your doctor about all known allergies before starting this medication.
Children
Gemtide 250 MCG Cartridge Injection is intended for adult use and should not be given to children unless specifically prescribed by a doctor.
Older Patients
Older patients should take Gemtide 250 MCG Cartridge Injection under medical supervision as they may be more susceptible to its side effects, particularly regarding kidney and liver health. It is advisable to discuss any health-related concerns with your doctor before starting this medicine.
Interactions of Gemtide 250 Mcg Cartridge Injection 3 Ml
Drug-Drug Interactions
Gemtide 250 MCG Cartridge Injection can interact with the following medicines:
- Cardiac glycosides (e.g., digoxin): Interaction due to altered calcium levels, potentially increasing the risk of digoxin toxicity.
- Thiazide diuretics (e.g., hydrochlorothiazide and indapamide): Interaction by increasing calcium reabsorption, potentially enhancing hypercalcemia risk.
- Loop diuretics (e.g., furosemide): Interaction through potential hypocalcemia, which may influence Teriparatide's efficacy.
Drug-Food Interactions
There are no specific food items known to interact negatively with Gemtide 250 MCG Cartridge Injection.
Drug-Disease Interactions
Gemtide 250 MCG Cartridge Injection can interact with the following diseases:
- Hypercalcemia (high calcium level): Exacerbates pre-existing hypercalcemia, reducing the safety of Teriparatide.
- Severe kidney impairment: May reduce Teriparatide clearance, increasing medication levels and risk of adverse effects.
- Metabolic bone diseases other than osteoporosis: May alter efficacy and safety due to differing pathophysiology.
- Unexplained elevations of alkaline phosphatase: Interaction suggests potential undiagnosed bone pathology, contraindicating Teriparatide.
- Prior radiation therapy involving the skeleton: Increases risk of osteosarcoma, a contraindication for Teriparatide.
- Skeletal malignancies or bone metastases: Inappropriate use, as Teriparatide may stimulate malignant cell growth.
Dosage of Gemtide 250 Mcg Cartridge Injection 3 Ml
Daily Dose
Your doctor will prescribe the daily dose of Gemtide 250 MCG Cartridge Injection. This may vary depending on your health status and how well you respond to the medicine. It is crucial to follow your doctor's instructions and not alter the dosage without consulting them first.
Over Dose
An overdose is highly unlikely for this medication as a skilled healthcare professional administers it.
Missed Dose
If you forget to take a dose of Gemtide 250 MCG Cartridge Injection as scheduled, consult your doctor for advice.
Storage
- Store Gemtide 250 MCG Cartridge Injection in a cool, dry place.
- Keep it away from direct light.
- Ensure the injection is kept out of reach of children.
- Always check the expiry date before use and do not use the injection if expired.
Special Dietary And Lifestyle Recommendation
- It is advisable to follow a diet rich in calcium and vitamin D while taking this medication, as these nutrients are essential for bone health.
- Regular monitoring of bone density is advised to assess the progress of osteoporosis management.
- Limiting the intake of caffeine and alcohol, which can inhibit calcium absorption, is also recommended.
- Smoking cessation is also advised as smoking can lower bone mineral density and increase fracture risk.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Osteoporosis |
| Drug Category | Hormone analogue |
| Therapeutic Category | Bone |
Frequently Asked Questions (FAQs)
What is Gemtide 250 MCG Cartridge Injection used for?
Gemtide 250 MCG Cartridge Injection is used to treat osteoporosis in postmenopausal women, men with primary or hypogonadal osteoporosis, and individuals with glucocorticoid-induced osteoporosis who are at high risk of fractures.
How does Gemtide 250 MCG Cartridge Injection work?
It contains Teriparatide, a parathyroid hormone analogue, which stimulates bone-forming cells to create new bone, increasing bone density and reducing fracture risk.
How is Gemtide 250 MCG Cartridge Injection given?
It is administered as a subcutaneous injection once daily, typically in the thigh or abdomen by a healthcare professional, as directed by your doctor.
What are the common side effects of Gemtide 250 MCG Cartridge Injection?
Common side effects include nausea, dizziness, leg cramps, injection site pain, and transient hypercalcemia.
Can pregnant or breastfeeding women use Gemtide 250 MCG Cartridge Injection?
It is not recommended for pregnant or breastfeeding women due to limited safety data. Consult your doctor for alternatives.
What precautions should I take while using Gemtide 250 MCG Cartridge Injection?
Inform your doctor of any medical conditions like hypercalcemia or prior skeletal radiation. Avoid exceeding the prescribed dose and monitor calcium levels as advised.
How should Gemtide 250 MCG Cartridge Injection be stored?
Store it in a refrigerator at 2°C to 8°C, away from light and heat. Do not freeze or use it beyond its expiry date.
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Manufacturer details
Country of origin: INDIA
References
- Forteo (teriparatide) label - accessdata.fda.gov. (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021318Orig1s056lbl.pdf
- Teriparatide: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06285
- Sondelbay | European Medicines Agency (EMA). (n.d.). European Medicines Agency (EMA). https://www.ema.europa.eu/en/medicines/human/EPAR/sondelbay
- Quattrocchi, E., & Kourlas, H. (2004). Teriparatide: A review. Clinical Therapeutics, 26(6), 841–854. https://doi.org/10.1016/s0149-2918(04)90128-2
- Blick, S. K. A., Dhillon, S., & Keam, S. J. (2008). Teriparatide. Drugs, 68(18), 2709–2737. https://doi.org/10.2165/0003495-200868180-00012
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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