Gemer Ds 1 Tablet 10

Sun Pharma Laboratories Ltd.

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Composition

Glimepiride (1 Mg) + Metformin (1000 Mg)

Gemer DS 1 Tablet is used to manage high blood sugar levels in adults with type 2 diabetes. It contains a "Double Strength" (DS) combination of Glimepiride and Metformin. Glimepiride stimulates the pancreas to release more insulin, while Metformin helps the body use its natural insulin more efficiently and lowers the amount of sugar produced by the liver.

This treatment provides powerful glycemic control, helping to keep blood sugar levels stable throughout the day. It is a vital tool for preventing long-term diabetic complications like vision loss, heart disease, and kidney failure. Take this medication with your first main meal of the day as directed by your doctor to achieve the best sugar control and minimize the risk of low blood sugar.

Gemer DS 1 Tablet is used to manage type 2 diabetes in adults when diet and exercise alone are insufficient. It assists with blood sugar control when single-agent therapy doesn't provide enough glycemic control and serves as an adjunct to diet and exercise for better glycemic management.

Here's how you should take Gemer DS 1 Tablet:

Swallow the tablet whole with a glass of water.
Do not chew, crush, or split the tablet.
Always follow the dose recommended by your doctor and don't adjust it without consulting your doctor first.

Gemer DS 1 Tablet is taken orally.

Gemer DS 1 Tablet may cause upper respiratory tract infection, diarrhea, nausea, vomiting, dizziness, headache, and hypoglycemia.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gemer DS 1 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a couple of tips that might help manage some of these side effects:

Diarrhoea: Try taking Gemer DS 1 Tablet with food or milk.
Hypoglycaemia: Consider taking this medicine with meals to lessen this effect.

Gemer DS 1 Tablet contains two active ingredients:

Glimepiride (1 mg): As a medium-to-long-acting sulfonylurea, glimepiride works by stimulating your pancreas's beta cells, causing them to produce more insulin. This action helps lower blood glucose levels.
Metformin (1000 mg): This biguanide reduces intestinal glucose absorption and decreases hepatic glucose production. It improves insulin sensitivity by increasing peripheral glucose uptake and utilisation. The extended-release formulation prolongs metformin absorption in the upper gastrointestinal tract, allowing for a steady release of the medication over time.

The combined action of these two components provides better glycemic control than either component used alone.

Pregnancy

Gemer DS 1 Tablet should be used during pregnancy only if clearly needed and the potential benefit justifies the potential risk to the unborn baby. To understand the risks and benefits, it is best to consult your doctor before taking this medicine.

Breastfeeding

Gemer DS 1 Tablet is secreted in human milk. If you are breastfeeding, you should stop nursing or stop using this medicine. Consult your doctor to understand the potential risks and benefits.

Alcohol

Avoid excessive alcohol intake while taking Gemer DS 1 Tablet. Alcohol can increase the risk of lactic acidosis and can potentiate the effect of this medicine on lactate metabolism.

Liver

Avoid use of Gemer DS 1 Tablet in patients with evidence of liver disease. If you have liver health issues, discuss them with your doctor before starting this medicine. This medicine may affect liver function.

Kidney

Gemer DS 1 Tablet is not recommended for use in patients with severe renal impairment. If you have any kidney problems, it's a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

Gemer DS 1 Tablet is not known to impact your ability to drive or operate machinery. As with any medicine, it's wise to see how it affects you before driving or operating heavy machines.

Allergy

If you're allergic to glimepiride, metformin or any other ingredients in Gemer DS 1 Tablet, avoid using this medication. An allergic reaction may occur if you do so.

Children

Gemer DS 1 Tablet is not recommended for use in children.

Older Patients

Older patients should take Gemer DS 1 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Gemer DS 1 Tablet interacts with the following medicines:

Non Steroidal Anti Inflammatory Drugs (NSAIDs): Medicines like ibuprofen and naproxen can potentially increase the risk of hypoglycemia when taken alongside Gemer DS 1 Tablet.
Beta Blockers: Medicines like atenolol and propranolol can intensify the blood sugarlowering effect of Gemer DS 1 Tablet and mask the symptoms of low blood sugar (hypoglycemia).
Diuretics: Medications such as furosemide or hydrochlorothiazide can lead to an increased blood sugar level, reducing the effectiveness of Gemer DS 1 Tablet.

Drug-Food Interactions

Foods high in fibre may decrease the absorption of metformin from the gut, reducing its effectiveness.

Drug-Disease Interactions

Gemer DS 1 Tablet interacts with the following diseases:

Liver Disease: Patients with liver disease should exercise caution as it could exacerbate their condition due to impaired metabolism and clearance of glimepiride and metformin.
Kidney Disease: This medicine could accumulate in the body if you have kidney disease, leading to potentially harmful effects.
Metabolic Acidosis: In conditions like diabetic ketoacidosis, lactic acidosis, or alcohol intoxication, Gemer DS 1 Tablet should not be used as it could worsen metabolic acidosis.

Daily Dose

Take the daily dose of Gemer DS 1 Tablet as prescribed by your doctor. The dosage could change based on your individual health condition and how you respond to the medicine. Always follow your doctor's instructions and do not exceed the prescribed dosage. For further details, refer to the package insert.

Over Dose

If you accidentally take more than your prescribed dose of Gemer DS 1 Tablet, you may experience symptoms such as dizziness and diarrhoea. If these symptoms persist or worsen, inform your doctor to get appropriate advice.

Missed Dose

If you forget to take your Gemer DS 1 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Keep Gemer DS 1 Tablet in a cool, dry place.
Protect it from light and moisture.
Ensure it's kept out of reach and sight of children.
Always check the expiry date on the package before taking this medicine.

Adopt a balanced and nutritious diet that's low in sugar to help manage your type 2 diabetes. This could include whole grains, lean proteins, fruits, and vegetables.
Regular physical activity, like walking or cycling for at least 30 minutes a day, can help improve your body's sensitivity to insulin, aiding in controlling your blood glucose levels.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic

What is the purpose of Gemer DS 1 Tablet?

It's a medicine used to manage type 2 diabetes in adults when diet and exercise alone aren't enough to control blood sugar levels.

How does Gemer DS 1 Tablet work?

The tablet contains two active ingredients that work together to control blood sugar. Glimepiride stimulates insulin production, while metformin reduces glucose production and increases its use by the body.

How should I take Gemer DS 1 Tablet?

The tablet should be taken exactly as advised by your doctor.

Can I use Gemer DS 1 Tablet for type 1 diabetes?

No, this medicine isn't suitable for managing type 1 diabetes or diabetic ketoacidosis. It's specifically designed to manage type 2 diabetes in adults.

What are the common side effects of Gemer DS 1 Tablet?

Common side effects may include upper respiratory tract infection, diarrhoea, nausea/vomiting, dizziness, headache, and low blood sugar (hypoglycaemia).

Can I take Gemer DS 1 Tablet if I'm pregnant or breastfeeding?

If you're pregnant or breastfeeding, consult your doctor before using this medicine as it can pass into human milk and may harm your baby.

Should I avoid any particular food or drink while taking Gemer DS 1 Tablet?

While taking this medicine, it's wise to avoid excessive alcohol intake as it can increase the risk of lactic acidosis a serious metabolic complication.

Last Updated On 25 Mar. 2026 | 11:52AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 9 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

Expiry on or after: August 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Unknown. (n.d.). Metformin hydrochloride Prolonged Release & Glimepiride tablets I.P. [Pharmaceutical Information]. https://www.sanofi.in/dam/jcr:6c1f15ea-d4af-4e93-b38c-91a76293b247/Amaryl%20M%20-%20PI.pdf
Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
AMARYL. (n.d.). AMARYL (glimepiride tablets) 1, 2, and 4 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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