Endoflozin S 10/50 Tablet 10

Curega Healthcare Pvt Ltd

Strip of 10 Units

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Old MRP ₹165

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Composition

Dapagliflozin (10 Mg) + Sitagliptin (50 Mg)

Endoflozin S 10/50 Tablet 10 is used to help control blood sugar in adults with type 2 diabetes, alongside diet and exercise, when a single medicine is not enough.

It combines dapagliflozin (10 mg), an SGLT2 inhibitor that helps the kidneys remove excess sugar in the urine, and sitagliptin (50 mg), a DPP-4 inhibitor that helps the body release more insulin after meals. Take it as prescribed, with or without food.

Staying well hydrated, keeping up good personal hygiene to reduce infections, a balanced diet and regular activity support better control alongside this medicine.

Tell your doctor about any kidney problems before starting, and about other medicines you take. Report signs of a urinary or genital infection, or severe stomach pain with fast or difficult breathing.

Endoflozin S 10/50 Tablet 10 is used to help control blood sugar in adults with type 2 diabetes, combining two medicines with different ways of lowering blood sugar.

Uses of Endoflozin S 10/50 Tablet 10 are:

Type 2 Diabetes: Helps control blood sugar when a single medicine is not enough.
Complication Risk: Better control helps reduce the risk of diabetes-related complications.

Here's how you should take Endoflozin S 10/50 Tablet 10:

Take the tablet orally as advised by your doctor.
Ensure you swallow the tablet whole with a glass of water.
Avoid crushing, cutting, or chewing the tablet.
Don't take more than the recommended dose without consulting your doctor.
It's essential not to stop taking this medicine without speaking to your doctor first.

Endoflozin S 10/50 Tablet 10 is taken orally.

Endoflozin S 10/50 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Endoflozin S 10/50 Tablet 10:

Genital: Fungal infections of the genital area.
Respiratory: Cold-like symptoms and upper respiratory tract infections.
Urinary: Urinary tract infections.
Neurological: Headache. Resting and keeping well hydrated can help with headaches.
Digestive: Loose motions (diarrhoea), feeling sick (nausea) and vomiting. Taking small sips of water and eating plain, simple food can help ease nausea.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Endoflozin S 10/50 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here's how to manage some common side effects:

Diarrhoea: Try taking Endoflozin S 10/50 Tablet 10 with food.
Nausea and vomiting: Taking this medicine after meals may help lessen this effect.

Endoflozin S 10/50 Tablet 10 combines two active ingredients that work together to help manage blood sugar levels:

Sitagliptin (50 mg): As a dipeptidyl peptidase-4 (DPP-4) inhibitor, sitagliptin helps increase insulin levels when needed and decrease the production of glucose when it's high.
Dapagliflozin (10 mg): This component acts as an inhibitor of sodium-glucose cotransporter 2 (SGLT2). By reducing kidnay glucose reabsorption and lowering the renal threshold for glucose, dapagliflozin helps manage blood sugar levels effectively.

Pregnancy

Endoflozin S 10/50 Tablet 10 is not recommended during pregnancy. If you are pregnant or planning a baby, ensure you discuss this with your doctor before starting this medicine.

Breastfeeding

This medicine is not advised for breastfeeding women. It's crucial to consult your doctor to understand the potential risks and benefits before taking Endoflozin S 10/50 Tablet 10.

Alcohol

While taking Endoflozin S 10/50 Tablet 10, it is advised to avoid excessive alcohol consumption. Alcohol may interfere with blood sugar control, increasing the risk of serious complications like diabetic ketoacidosis.

Liver

If you have liver health issues, it's best to consult your doctor before taking Endoflozin S 10/50 Tablet 10. This is because liver function may be affected by this medicine.

Kidney

This medicine is contraindicated in severe kidney impairment or dialysis.

Use In Driving And Operating Machinery

There's no known effect of Endoflozin S 10/50 Tablet 10 on your ability to drive or use machines. Still, if you feel unwell after taking the medicine, avoid such activities until you feel better.

Allergy

Do not take Endoflozin S 10/50 Tablet 10 if you have had serious allergic reactions to dapagliflozin, sitagliptin, or any other components of the medicine.

Children

This medicine is meant for adults. It should not be given to children under 18 years of age unless specifically advised by a doctor.

Older Patients

For older patients above 70 years of age, caution is advised while taking Endoflozin S 10/50 Tablet 10. Older patients might have liver and kidney issues and could be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Endoflozin S 10/50 Tablet 10 interacts with the following medicines:

Anti-infective agents such as Rifampin: Rifampin, a powerful antibiotic often used to treat bacterial infections like tuberculosis, may reduce the effectiveness of Endoflozin S 10/50 Tablet 10.
Anti-coagulants such as digoxin: The concomitant use may alter the blood levels of either medicine, potentially increasing the risk of toxicity or reducing their effectiveness.
Nonsteroidal Anti-inflammatory Agent such as Mefenamic Acid: This combination could increase the risk of gastrointestinal side effects such as ulcers or bleeding, as well as compromise the effectiveness of either medication.

Drug-Disease Interactions

Endoflozin S 10/50 Tablet 10 interacts with the following diseases:

Severe kidney impairment: If you suffer from severe kidney impairment or are in end-stage kidney disease or on dialysis, you should avoid taking Endoflozin S 10/50 Tablet 10.
Diabetic ketoacidosis: In patients with acute or chronic metabolic acidosis, including diabetic ketoacidosis, this medicine may not be advisable.
Pancreatitis: If you have a history of pancreatitis, caution is advised when taking this medicine as its impact hasn't been fully studied.

Daily Dose

Your doctor will prescribe the daily dosage of Endoflozin S 10/50 Tablet 10. It's crucial to follow these instructions and not exceed the recommended dose without consulting your doctor.

Over Dose

If you accidentally take more than your prescribed dose of Endoflozin S 10/50 Tablet 10, you may experience symptoms like nausea and diarrhoea. Inform your doctor if these symptoms persist.

Missed Dose

If you forget to take your Endoflozin S 10/50 Tablet 10, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one. Never increase your dosage without consulting your doctor.

Keep Endoflozin S 10/50 Tablet 10 at room temperature below 30°C.
Make sure it's kept away from moisture.
Always keep this medicine out of the reach of children.
Use the tablet before its expiry date for maximum effectiveness.

Regularly engage in physical activity. Moderate exercise such as walking or swimming can help manage blood glucose levels. Always consult your doctor before starting any new exercise regimen.
Maintain a balanced diet. Opt for foods with low sugar content and high fibre, such as whole grains, fruits, and vegetables to support effective diabetes management. Remember to consult your doctor for personalised dietary advice.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	DPP-4 Inhibitor, SGLT2 Inhibitor
Therapeutic Category	Antidiabetic

What is Endoflozin S 10/50 Tablet 10 used for?

This medicine is used to improve blood sugar control in adults with type 2 diabetes, alongside diet and exercise.

How does Endoflozin S 10/50 Tablet 10 work?

It contains two active ingredients that lower blood glucose levels: dapagliflozin increases glucose excretion, and sitagliptin boosts insulin secretion.

How should I take Endoflozin S 10/50 Tablet 10?

You should take one tablet orally once a day with your morning meal. Remember not to crush, cut, or chew the tablet.

What are the common side effects of Endoflozin S 10/50 Tablet 10?

Common side effects include female genital yeast infections, nasopharyngitis (common cold), urinary tract infections, headache, diarrhoea, nausea and vomiting, and upper respiratory tract infection.

What precautions should I take while using Endoflozin S 10/50 Tablet 10?

If you have a history of pancreatitis or severe kidney problems, consult your doctor before taking this medicine. Stay hydrated and maintain good hygiene to avoid infections.

Can Endoflozin S 10/50 Tablet 10 interact with other medicines?

Yes, Sitara-D 50/10 Tablet can interact with other medications, such as Rifampin (an antibiotic), Digoxin (used for heart conditions), and Mefenamic Acid (a pain reliever). These interactions may affect the effectiveness or increase the risk of side effects of either medicine. Always inform your doctor about all medications you are taking before starting Sitara-D 50/10 Tablet.

Last Updated On 03 Jul. 2026 | 5:56AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 10 years

PhD in Chemistry

Reviewed by

Pragati Bhosale

Medical Content Reviewer | 5 years

M. Pharmacy

Check out Editorial Policy

Manufacturer details

Office No -4, C/2 Building, Simplicity, Handewadi Road , Hadapsar, Pune - 412308 Maharashtra, India

Country of origin: INDIA

Expiry on or after: November 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

FARXIGA® (dapagliflozin) tablets, for oral use . (N.d.). Fda.Gov. Retrieved November 29, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Dapagliflozin and Sitagliptin tablets. (N.d.). Msnlabs.Com. Retrieved November 29, 2024, from https://www.msnlabs.com/img/RxList/PrescribingInformation_MFLL0009-00.pdf
Merck Sharp & Dohme Corp. (2006). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021995s019lbl.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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