Home/Blog/Health Conditions/Aesthetic & Skin Care/Glycerine Uses for Skin and Face: Benefits and Side Effects

Glycerine Uses for Skin and Face: Benefits and Side Effects

Last updated on : 08 Jul, 2025

Read time : 9 min

Glycerine is a versatile ingredient that has been used for centuries in skincare routines. Its exceptional moisturising and protective properties make it a popular choice for those looking to enhance their skin’s health and appearance. From hydrating the skin to reducing the appearance of wrinkles, glycerine uses for skin and face are numerous and well-documented. In this article, we will explore the benefits of glycerine and how it can help you achieve glowing, healthy skin.

What is Glycerin?

Glycerin, also known as glycerol, is a colourless, odourless, and viscous liquid that is derived from vegetable oils and animal fats. It is a simple polyol compound with the chemical formula C₃H₈O₃. Glycerin is non-toxic, sweet-tasting, and hygroscopic, meaning it attracts and retains moisture. This property makes it an effective humectant, drawing water from the deeper layers of the skin to the surface, enhancing hydration and elasticity. Glycerin is widely used in skincare products due to its ability to improve the skin’s moisture content and overall appearance. In the next section, we will delve into the various benefits of glycerine for the skin and face.

Uses of Glycerine

Glycerine has a wide range of applications across various industries.

1. Skincare

Glycerine offers numerous benefits for skin hydration and protection:

  • Acts as a humectant, drawing moisture from the environment and skin layers for deep hydration.
  • Strengthens the skin barrier, preventing moisture loss and protecting sensitive skin.
  • Combats dryness by retaining moisture, especially when paired with occlusives like dimethicone.
  • Provides non-comedogenic hydration for acne-prone skin, balancing moisture without clogging pores.

2. Hair Care

Glycerine offers multiple benefits for hair care:

  • Hydrates hair and scalp, reducing dryness and flaking
  • Improves softness and manageability, especially for curly, thick, or dry hair
  • Strengthens hair, helping  prevent breakage and split ends
  • Adds shine and maintains healthy hair for all types, including straight, wavy, and curly

3. Medical Uses

Glycerine has a range of uses in different fields:

  • In medicine, glycerine plays multiple roles. It is often used topically to treat dry skin conditions like xerosis and ichthyosis by improving skin hydration and barrier function. Rectally, it acts as a mild osmotic laxative, helping relieve occasional constipation by drawing water into the intestines. Oral glycerine solutions may be used to temporarily lower intraocular pressure in acute angle-closure glaucoma emergencies. In transfusion medicine, glycerine is also used to preserve red blood cells before freezing.
  • Note: The use of oral glycerine for intraocular pressure management should always be supervised by a healthcare provider and is not a routine treatment.

4. Food Industry

Glycerine is widely used in the food industry for various purposes:

  • Prevents moisture loss in dried fruits, nutrition bars, and candy.
  • Acts as a flavour carrier in soft drinks and confections, evenly distributing flavourings.
  • Preserves botanical extracts and maintains texture in baked goods like cakes.

5. Household Applications

Glycerine is a versatile ingredient found in a variety of personal care and cleaning products:

  • Used in toothpaste, mouthwashes, shaving cream, soaps, and lubricants for its moisturising and lubricating properties.
  • In skin cleansers, it softens the skin during the cleansing process.
  • Incorporated into bio-ink formulations for bioprinting, adding viscosity without large protein or saccharide molecules.
Glycerine and Lemon Juice Toner: A toner to balance skin tone and texture. Ingredients: 1 tablespoon of glycerine, 1 tablespoon of fresh lemon juice, 1 cup of distilled water.
Instructions: Combine glycerine and lemon juice in a bottle. Add distilled water and mix well. Apply to the face with a cotton pad after cleansing.
Benefits: Balances skin tone. Helps in exfoliation and brightening.
Note: Lemon juice can irritate sensitive skin or cause photosensitivity. Always patch test first and avoid sun exposure after use.

Benefits of Glycerine

Glycerine offers numerous skincare benefits, making it a staple in many products:

  • Hydration: As a humectant, glycerine draws moisture into the skin, providing long-lasting hydration, which is ideal for dry or dehydrated skin and conditions like eczema and dermatitis.
  • Anti-Aging: By plumping the skin and filling gaps in the intercellular matrix, glycerine helps reduce fine lines and wrinkles, promoting a youthful appearance.
  • Skin Barrier: It strengthens the skin’s barrier, protecting against moisture loss, environmental stressors, and irritation.
  • Antimicrobial: While not strongly antimicrobial on its own, glycerine can enhance the effects of antimicrobial agents such as alcohol. This is why it is often used in hand sanitizers and wound care products.
  • Skin-Replenishing: Glycerine aids in healthy skin cell maturation, helping  treat conditions like psoriasis by reducing inflammation and supporting wound healing.
  • Natural Preservative: While not a preservative on its own, glycerine’s moisture-retaining properties help maintain the stability of skincare formulations when used with other ingredients.

How to Use Glycerine on Face?

Glycerine can be easily incorporated into your daily skincare routine to maximise its benefits for your skin and face. Here are some simple ways to use glycerine on your face:

  • Apply products containing glycerine immediately after showering to lock in moisture and keep your skin hydrated.
  • Choose a face wash that includes glycerine to avoid harsh agents and maintain gentle skin care.
  • Use a moisturiser or gel cream containing glycerine, especially before bed, to enhance skin hydration and elasticity.
  • Apply sunscreen with glycerine to protect your skin from the sun while maintaining hydration.
  • Add glycerine to your skin cleansers to soften the skin during the cleansing process.

Avoid applying undiluted glycerine directly to the face in dry climates, as it may draw moisture from deeper skin layers, causing dehydration.

While glycerine is generally well-tolerated, it’s important to be aware of potential side effects.

Side Effects of Glycerine

Although glycerine is considered safe for most people, there are some potential side effects to keep in mind:

  • Rarely, glycerine can cause allergic reactions such as rash, hives, itching, redness, or peeling skin.
  • Allergic contact dermatitis is very rare but can occur; patch testing by a dermatologist may be helpful.
  • Although uncommon, some individuals may experience skin irritation or sensitivity.

If you experience any adverse reactions while using glycerine on your face, discontinue use and consult with your doctor or dermatologist.

Conclusion

Glycerine is a powerhouse ingredient in modern skincare and personal care products. Its humectant properties make it a top choice for maintaining skin hydration, improving elasticity, and enhancing skin barrier function. It is suitable for all skin types—including dry, oily, combination, and sensitive—and can be found in a wide range of cleansers, moisturisers, and serums. When used correctly, glycerine can help you achieve softer, more supple skin without significant risk of irritation. However, always be mindful of how your skin reacts, and consult a dermatologist if you have any concerns or underlying skin conditions. 

Frequently Asked Questions (FAQs)

What are the uses of glycerine?

Glycerine is used in skincare, haircare, oral hygiene, pharmaceuticals, and as a humectant in various products like cosmetics, cough syrups, and food items.

Can you apply glycerine directly to skin?

It is advisable to use glycerine as an ingredient in products rather than applying pure glycerine directly to the skin, as it can dehydrate and irritate the skin.

What is 99% glycerine used for?

Glycerine at concentrations up to 99.4% is used in some beauty products for its humectant properties, helping to retain moisture in the skin.

Is glycerine safe to use daily?

Glycerine is generally recognised as safe, non-toxic, and non-irritating for daily use on most skin types, including dry, oily, and combination skin.

Why is glycerine used in the mouth?

Glycerine is used in oral care products like toothpaste and mouthwashes due to its humectant and lubricant properties, helping to maintain moisture and hygiene.

What are the side effects of glycerine?

Common side effects are mostly associated with rectal use and include excessive bowel activity, cramping, rectal irritation, and rectal pain. Rarely, it can cause skin irritation or allergic reactions.

What does glycerine do for hair?

Glycerine deeply moisturises and hydrates hair, improves manageability, reduces frizz, strengthens hair, and helps prevent split ends and breakage.

Can glycerine remove dark spots?

There is no evidence suggesting that glycerine can remove dark spots. Its primary benefits are related to moisturising and hydrating the skin.

Can I mix glycerine with water?

While you can mix glycerine with water, it is recommended to use it as part of a formulated product to avoid potential dehydration or irritation of the skin.

Does glycerine expire?

There is no specific mention of glycerine expiring, but it is important to check the product’s expiration date and stability when stored properly.

Can we apply glycerine on lips?

Glycerine can be beneficial for lip care due to its moisturising properties, but it is best used in formulated lip products rather than applying pure glycerine directly.

Can I use glycerine on my face?

Yes, glycerine is suitable for use on the face as part of moisturisers, cleansers, or other skincare products, helping to retain moisture and support the skin barrier function.

References:

  • Chen, H. J., Lee, P. Y., Chen, C. Y., Huang, S. L., Huang, B. W., Dai, F. J., Chau, C. F., Chen, C. S., & Lin, Y. S. (2022). Moisture retention of glycerin solutions with various concentrations: a comparative study. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-13452-2
  • Fluhr, J. W., Darlenski, R., & Surber, C. (2008). Glycerol and the skin: holistic approach to its origin and functions. The British Journal of Dermatology, 159(1), 23–34. https://doi.org/10.1111/j.1365-2133.2008.08643.x
  • Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., Gill, L. J., & Heldreth, B. (2019). Safety Assessment of Glycerin as Used in Cosmetics. International Journal of Toxicology, 38(3_suppl), 6S22S. https://doi.org/10.1177/1091581819883820
  • Enhancing skin hydration and barrier function via skin penetration of monoglycerides and sustained glycerin release. (2017). Journal of the American Academy of Dermatology, 76(6), AB122. https://doi.org/10.1016/j.jaad.2017.04.476
  • Roussel, L., Atrux-Tallau, N., & Pirot, F. (2012). Glycerol as a Skin Barrier Influencing Humectant. Treatment of Dry Skin Syndrome, 473–480. https://doi.org/10.1007/978-3-642-27606-4_32
Select Category
Was this article useful?
40 people find this information helpful

Meet our Health Experts

View All
Dr. Nikhil Ambatkar
Dr. Nikhil Ambatkar

Ph.D, M.Tech, B.Tech

7 years
Dr. Sachin Singh
Dr. Sachin Singh

MBBS

6 years
Dr. Mandeep Chadha
Dr. Mandeep Chadha

MBBS, DNB (OBGY)

11 years
Amatul Ameen
Amatul Ameen

B. Pharm, MSc.

13 years
Amit Sharma
Amit Sharma

B. Pharm

4 years
Rohini Mankar
Rohini Mankar

Bsc. Zoology, Masters of Public Health

12 years
Dr. Divya Mandial
Dr. Divya Mandial

PhD in Chemistry

9 years
Dr. Sonia Gupta
Dr. Sonia Gupta

BDS

7 years
Saloni Bhardwaj Sharma
Saloni Bhardwaj Sharma

B.Pharm, M.Pharm

4 years
Dr. Chhavi Rosha
Dr. Chhavi Rosha

BAMS, FMC, MD Resident

9 years
Dr. Lakshmi Vaswani
Dr. Lakshmi Vaswani

MBBS, Diploma Pathology, MBA (Healthcare Services)

14 years

Follow us on

Disclaimer

Our healthcare experts have carefully reviewed and compiled the information presented here to ensure accuracy and trustworthiness. It is important to note that this information serves as a general overview of the topic and is for informational purposes only. It is not intended to diagnose, prevent, or cure any health problem. This page does not establish a doctor-patient relationship, nor does it replace the advice or consultation of a registered medical practitioner. We recommend seeking guidance from your registered medical practitioner for any questions or concerns regarding your medical condition.

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Registered Office Address

Intellihealth Solutions Private Limited
Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346

Grievance Officer

Name: Chandrasekhar Swaminathan

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Playstore
Apple App  Store

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v4.0.2

copyright

2025 - Truemeds | All rights reserved. Our content is for informational purposes only. See additional information.

Trust Certified

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner