Lotace 50 H Tablet 10

Karnataka Antibiotics & Pharmaceuticals Ltd(kapl)

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MRP ~~₹72~~

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Composition

Hydrochlorothiazide (12.5 Mg) + Losartan (50 Mg)

Lotace 50 H Tablet 10 is used to manage high blood pressure (hypertension). It combines Losartan (50 mg), an angiotensin II receptor blocker that relaxes blood vessels, and Hydrochlorothiazide (12.5 mg), a diuretic that removes excess salt and water from the body. This combination helps lower blood pressure effectively.

This tablet is also useful in managing oedema due to heart, kidney, or liver diseases. Furthermore, it aids in protecting the kidneys from damage caused by diabetes and reduces the risk of strokes in patients with left ventricular hypertrophy.

Before you start taking this medicine, it's crucial to consult your doctor regarding the appropriate dosage and frequency. Inform your doctor about any pre-existing health conditions or ongoing medications you're taking. If you notice any side effects during treatment, immediately inform your doctor. Remember to continue taking the medicine for the duration your doctor prescribes.

Lotace 50 H Tablet 10 is used for the following:

Reducing high blood pressure levels, also known as hypertension
Managing fluid build-up and swelling caused by heart diseases
Assisting in controlling fluid retention related to kidney ailments
Helping with managing oedema due to liver conditions
Protecting the kidneys from damage in diabetes sufferers
Decreasing the risk of strokes in people with left ventricular hypertrophy

Swallow the whole tablet with a glass of water.
Ensure you do not crush or chew the tablet.
Not exceeding the recommended dose is crucial.
Do not stop taking this medicine suddenly without discussing it with your doctor.

Lotace 50 H Tablet 10 is taken orally.

Lotace 50 H Tablet 10 may lead to the following side effects:

Dizziness
Headache
Feeling extremely tired
Nausea
Diarrhoea
Mild skin rash

Managing the Side Effects:

The most common side effects are temporary and generally harmless, and they are resolved by discontinuing the use of Lotace 50 H Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips for managing common side effects:

Dizziness: Try taking Lotace 50 H Tablet 10 at bedtime to minimise its impact on your daily activities.
Diarrhoea: Consider taking this medicine with food or milk to lessen this particular effect.

Lotace 50 H Tablet 10 consists of two active ingredients:

Hydrochlorothiazide (12.5 mg): This ingredient is a diuretic, which means it increases urine production. Doing so helps eliminate excess water and salt from your body. The result is a reduced fluid volume within your blood vessels, effectively lowering blood pressure.
Losartan (50 mg): Belonging to the class of angiotensin II receptor blockers (ARBs), losartan works by inhibiting the binding of angiotensin II - a substance that narrows blood vessels - to its receptors. When this happens, your blood vessels relax and widen, decreasing resistance to blood flow and thus reducing blood pressure.

Pregnancy

Lotace 50 H Tablet 10 is contraindicated during pregnancy, particularly in the second and third trimesters. As it could harm the unborn baby, if you are pregnant or planning to conceive, it is critical to discuss this with your doctor before starting this medicine.

Breastfeeding

Breastfeeding women should avoid taking Lotace 50 H Tablet 10. If you are nursing a child, consult your doctor to understand the potential risks and benefits.

Alcohol

While taking Lotace 50 H Tablet 10, caution is advised when consuming alcohol as it might enhance some side effects like dizziness. Discuss this with your doctor for better guidance.

Liver

If you have a history of liver disease, please proceed with caution while taking Lotace 50 H Tablet 10. It's best to discuss any liver-related concerns with your doctor before starting this medication.

Kidney

Caution is advised before using Lotace 50 H Tablet 10 if you have any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

You may experience dizziness or tiredness due to Lotace 50 H Tablet 10. In such cases, avoid driving or operating heavy machinery until you know how this medicine affects you.

Allergy

Lotace 50 H Tablet 10 should not be taken if you are allergic to hydrochlorothiazide, losartan or any other ingredient in the medication. If you have a history of allergies, discuss them with your doctor before starting this medicine.

Children

Lotace 50 H Tablet 10 is primarily meant for adults. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Lotace 50 H Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Lotace 50 H Tablet 10 interacts with the following medicines:

Mood stabilizers such as Lithium: When taken together, Lotace 50 H Tablet 10 can increase the risk of lithium toxicity.
Non-steroidal anti-inflammatory medicines (NSAIDs): Medicines such as ibuprofen and naproxen can reduce the blood pressure-lowering effect of Lotace 50 H Tablet 10 and increase the risk of kidney damage.
Potassium supplements or salt substitutes containing potassium: These can interact with Lotace 50 H Tablet 10, increasing the risk of high potassium levels in your blood (hyperkalemia).
Insulin and oral antidiabetic medications: Lotace 50 H Tablet 10 can affect blood glucose levels, potentially reducing the effectiveness of medicines like insulin and metformin.

Drug-Food Interactions

Certain foods may interact with Lotace 50 H Tablet 10. It's essential to:

Avoid potassium-rich foods: Consuming foods high in potassium while taking Lotace 50 H Tablet 10 could lead to hyperkalemia.

Drug-Disease Interactions

Lotace 50 H Tablet 10 interacts with the following diseases:

Liver disease: Patients with liver disease should exercise caution as this medicine could exacerbate their condition.
Diabetes: Lotace 50 H Tablet 10 could impact blood sugar control, making it essential to monitor glucose levels closely when on this medication.
Gout: This medicine might increase uric acid levels in people with gout.

Daily Dose

The recommended dose of Lotace 50 H Tablet 10 should be taken as instructed by your doctor. The dosage may vary according to the severity of your condition and how well you respond to the medication. It's crucial not to exceed this dosage without consulting your doctor.

Over Dose

Overdosing on Lotace 50 H Tablet 10 can lead to common side effects such as dizziness, headache, and nausea. If you suspect an overdose and these symptoms persist, it is important to inform your doctor.

Missed Dose

If you miss a dose of Lotace 50 H Tablet 10, take it as soon as you recall. However, if it's nearly time for your next dose, skip the missed one and continue with your usual schedule. Do not increase your dosage without consulting your doctor.

Keep Lotace 50 H Tablet 10 in a closed container at room temperature below 30°C.
Protect the medication from excessive light and moisture.
Keep out of reach of children.

Incorporate a low-sodium diet into your lifestyle, as this can assist in managing high blood pressure, a condition Lotace 50 H Tablet 10 is used to manage.
Regular physical activity or exercise, as approved by your doctor, is beneficial in maintaining healthy blood pressure levels.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Edema
Drug Category	Angiotensin II receptor blocker, Thiazide diuretic
Therapeutic Category	Antihypertensive

What is Lotace 50 H Tablet 10 used for?

Lotace 50 H Tablet 10 is primarily used to manage high blood pressure and oedema caused by heart, kidney, or liver diseases.

How does Lotace 50 H Tablet 10 work?

This medicine works by combining the effects of hydrochlorothiazide, a diuretic that removes excess water and salt from your body, and losartan, a medication that relaxes and widens your blood vessels.

How should I take Lotace 50 H Tablet 10?

Lotace 50 H Tablet 10 is taken with or without food. Always follow your doctor's instructions when taking this medicine.

What are the common side effects of Lotace 50 H Tablet 10?

Common side effects may include dizziness, headache, fatigue, nausea, diarrhoea, and mild skin rash. If these persist or worsen, consult your doctor.

Are there any precautions to take while using Lotace 50 H Tablet 10?

You should avoid using Lotace 50 H Tablet 10 if you're allergic to its ingredients or pregnant. It's also best to avoid excessive sun exposure as the medicine may cause photosensitivity.

Can Lotace 50 H Tablet 10 interact with other medications?

Yes, it can interact with several medications, including lithium, NSAIDs, potassium supplements or substitutes, and insulin or oral antidiabetic medications. Always inform your doctor about all the medicines you're taking.

How should I store Lotace 50 H Tablet 10?

Store at room temperature in a tightly closed container protected from light and moisture. Keep out of reach of children and pets.

Last Updated On 13 May. 2025 | 11:19AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

2H63+FP4, Rajajinagar, Bengaluru, Karnataka 560010

Country of origin: INDIA

Expiry on or after: November 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Hydrochlorothiazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00999
Hydrochlorothiazide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682571.html
PubChem. (n.d.). Hydrochlorothiazide. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/3639
Losartan: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00678
Losartan: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a695008.html
PubChem. (n.d.). Losartan. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/3961

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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