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Hydrochlorothiazide + Losartan

Antihypertensive

Uses of Hydrochlorothiazide + Losartan

  • Hydrochlorothiazide + Losartan is used in the management of high blood pressure (hypertension) when a single medication is not sufficient.
  • This combination is also prescribed to reduce the risk of stroke and kidney damage in patients with high blood pressure and diabetes.

Side effects of Hydrochlorothiazide + Losartan

  • Dizziness
  • Fatigue
  • Low blood pressure (hypotension)
  • Increased urination
  • Electrolyte imbalance
  • Muscle cramps

How Hydrochlorothiazide + Losartan works

  • Hydrochlorothiazide + Losartan is an antihypertensive combination.
  • Losartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels, allowing blood to flow more easily and lowering blood pressure.
  • Hydrochlorothiazide is a diuretic (water pill) that helps the body remove excess salt and water through urine, further reducing blood pressure and preventing fluid retention.
     

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 4 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Hydrochlorothiazide + Losartan is available in oral tablet form.

Age and Dose Restrictions

  • This combination is not recommended for children under 18 years.

Contraindications

  • This medication is contraindicated in patients with severe kidney disease, liver impairment, anuria (inability to produce urine), or a history of allergic reactions to sulfa medications.

Other Medications to Avoid

  • Certain medications can interact with Hydrochlorothiazide + Losartan and may lead to serious side effects. Avoid taking NSAIDs (ibuprofen, naproxen), lithium, potassium supplements, other diuretics (furosemide), and ACE inhibitors (ramipril, enalapril) without consulting a doctor.

Overdose and Missed Dose

  • An overdose of this medication can cause severe dizziness, low blood pressure, electrolyte imbalance, and dehydration. If an overdose occurs, seek immediate medical attention.
  • If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

Management of Side Effects

  • If you experience dizziness or fatigue, sit or lie down until you feel better. Staying hydrated can help reduce dehydration caused by the diuretic component. If you have muscle cramps or weakness, you may need to monitor your potassium levels and adjust your diet accordingly. Consult your doctor if side effects persist or worsen.

Use in Driving and Operating Machinery

  • This combination can cause dizziness and lightheadedness, especially when standing up suddenly. Until you know how the medication affects you, avoid driving, operating heavy machinery, or engaging in activities that require focus.

Use in Pregnancy and Lactation

  • Hydrochlorothiazide + Losartan is not safe during pregnancy, especially in the second and third trimesters, as it can harm the developing baby. Breastfeeding mothers should avoid this medication, as Hydrochlorothiazide can reduce milk production, and Losartan may pass into breast milk.

Caution in Other Conditions

  • Patients with kidney disease, liver disease, heart failure, diabetes, or electrolyte imbalances (low potassium or sodium levels) should take this medication with caution. Regular blood pressure monitoring and electrolyte checks are essential to avoid complications.

Special Dietary and Lifestyle Recommendations

  • Limit sodium intake by reducing processed and salty foods to enhance the effectiveness of blood pressure control.
  • Stay hydrated but avoid excessive fluid intake, as this medication can affect electrolyte balance.
  • Increase potassium-rich foods such as bananas, spinach, and sweet potatoes to prevent potassium depletion caused by hydrochlorothiazide.

Frequently asked questions

This combination starts working within 1 to 2 hours, but its full effect on blood pressure may take up to 3 to 6 weeks.

Yes, the diuretic component (Hydrochlorothiazide) increases urine output, which can lead to dehydration if adequate fluids are not consumed.

This medication is generally safe for the kidneys, but in some cases, it may reduce kidney function, especially in patients with pre-existing kidney disease. Regular kidney function tests are recommended.

Potassium supplements should be used only under medical supervision, as Losartan can increase potassium levels, while Hydrochlorothiazide can decrease them. A balanced diet is usually preferred over supplements.

Yes, Hydrochlorothiazide + Losartan is commonly used for long-term blood pressure management. However, regular blood pressure, kidney function, and electrolyte monitoring are required.

Terms & Conditions


List of Medicines for Hydrochlorothiazide + Losartan

Cosart H Tablet 10
Cosart H Tablet 10
Cipla Ltd.
Pack of 10 Units
₹64.95
MRP ₹106.48
39% OFF
Losakind H Tablet 10
Losakind H Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
₹74.4
MRP ₹93
20% OFF
Covance D Tablet 10
Covance D Tablet 10
Sun Pharmaceutical Industries Ltd
Pack of 10 Units
₹148.8
MRP ₹186
20% OFF
Giftan Hc Tablet 10
Giftan Hc Tablet 10
Systopic Laboratories Private Limited
Pack of 10 Units
₹40
MRP ₹50
20% OFF
Losar H Tablet 15
Losar H Tablet 15
Torrent Pharmaceuticals Ltd.
Pack of 15 Units
₹245.28
MRP ₹306.6
20% OFF
Losatan H Tablet 10
Losatan H Tablet 10
Zydus Healthcare Ltd
Pack of 10 Units
₹71.11
MRP ₹142.5
50.1% OFF
Repace H Tablet 10
Repace H Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹148.8
MRP ₹186
20% OFF
Ltk H Tablet 10
Ltk H Tablet 10
Unison Pharmaceuticals
Pack of 10 Units
₹34.8
MRP ₹43.5
20% OFF

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