Admegion 400 Tablet 10

Admegion 400 Tablet is used to manage liver conditions where bile flow is reduced, helping to improve bile flow and relieve symptoms such as itching and tiredness in people with liver disease.

Uses of Admegion 400 Tablet are:

• Intrahepatic Cholestasis in Chronic Liver Disease: This medicine helps improve bile flow within the liver in adults with long-term liver disease, including cirrhosis.
• Intrahepatic Cholestasis of Pregnancy: It is used to manage the condition where bile flow slows in pregnancy, causing severe itching.
• Fatigue in Chronic Liver Disease: It helps relieve the tiredness that often occurs with long-term liver conditions.

Follow these instructions while taking Admegion 400 Tablet:

• Swallow the tablet whole with a glass of water.
• Do not crush, chew or break the tablet, as it may have a protective coating.
• Take this medicine earlier in the day rather than at night, as it may disturb your sleep.
• It is best taken on an empty stomach or between meals for better absorption.
• Do not stop taking this medicine without consulting your doctor first.
• For specific advice on timing and duration, consult your doctor.

Admegion 400 Tablet is taken orally.

Admegion 400 Tablet contains Ademetionine 1,4-butanedisulfonate (SD4) equivalent to Ademetionine ion 400 mg, which works on the body through three main pathways:

• Transmethylation: Ademetionine donates methyl groups (small chemical units) to various molecules in the body, including membrane phospholipids (fats that form cell membranes). This process increases the fluidity of liver cell membranes and supports the function of transporters that move bile salts, thereby improving bile flow.
• Transsulfuration: Ademetionine is converted into glutathione, the body's major intracellular antioxidant (a substance that protects cells from damage by harmful molecules called free radicals). This protects liver cells from oxidative injury and helps maintain healthy liver function.
• Aminopropylation: Ademetionine provides aminopropyl groups needed to make polyamines (molecules essential for cell growth), which support tissue regeneration and repair in the liver.

• Store below 25°C in a cool, dry place away from direct heat and sunlight.
• Keep the tablets in their sealed blister strip until you are ready to take them, as ademetionine is sensitive to moisture.
• Do not use after the expiry date printed on the pack.
• Keep out of the sight and reach of children.

• Include a variety of nutritious foods: A balanced diet with vegetables, fruits, whole grains and adequate protein can support general nutritional health while the underlying liver condition is being treated.
• Keep a regular sleep routine: Go to bed and wake up at consistent times, particularly if you notice restlessness or difficulty sleeping during treatment.