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Naproxen + Domperidone

Migraine Drugs

Uses of Naproxen + Domperidone

  • Naproxen + Domperidone is used in the treatment and prevention of migraines.

Side effects of Naproxen + Domperidone

  • Swelling on ankle/feet
  • Unusual tiredness
  • Mood changes
  • Hot flashes 
  • Confusion
  • Headache
  • Ringing in the ears 
  • Changes in sight

How Naproxen + Domperidone works

  • Naproxen is a non-selective, non-steroidal anti-inflammatory drug. It works by reducing prostaglandin synthesis by inhibiting COX1 and COX2 enzymes. 
  • Domperidone is an anti-emetic drug that also delays gastrointestinal emptying. It is a prokinetic which shows the action by blocking dopamine receptors. The dopamine receptor blocking property is responsible for the antiemetic action of domperidone. 

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Naproxen + Domperidone can be taken orally (tablet).

Age And Dose Restrictions

  • It can be used by adults and children over 12 years of age.

Contraindications 

  • It is contraindicated in patients with a history of hypersensitivity to naproxen or domperidone, patients with kidney disease, heart disease, liver disease or asthma.

Medications To Avoid With This Drug 

  • Avoid taking anticoagulants (warfarin), NSAIDs (ketorolac), ACE inhibitors (ramipril), corticosteroids (prednisone), aminoglycoside antibiotics (amikacin), and antiarrhythmic medications (quinidine). These medications may alter the safety and effectiveness of this combination.

Overdose And Missed Dose

  • Overdosage may cause extreme tiredness, drowsiness, stomach pain, heartburn, nausea, vomiting, sleepiness, uncontrolled eye movements, unusual tongue movements, and abnormal posture. Consult your doctor if you experience any of these side effects. Adhere to the prescribed dosage of this combination.
  • If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • The side effects are temporary and resolve when this combination is discontinued. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This medicine can cause confusion. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • Caution is advised in pregnant women. Its use in breastfeeding women should be done only if prescribed by a doctor.

Caution In Other Conditions

  • Caution should be taken in the elderly, especially in liver, kidney, and heart disease patients.

Special Dietary And Lifestyle Recommendation

  • Avoid skipping meals, as irregular eating patterns contribute to migraines.
  • Practice stress-relief techniques like meditation, yoga, deep breathing, and mindfulness to reduce migraine triggers.
  • Try sleeping in a dark room during the migraine episode. 
  • Maintain a consistent sleep schedule and ensure you get restorative sleep each night. 
  • Engage in regular physical activity but avoid excessive exertion during the migraine attack. 
  • Apply a cold compress to your forehead for 15 minutes to ease the pain. 
  • Apply gentle pressure to specific painful points on your head, neck, and shoulder to relieve the migraine headache. 

Frequently asked questions

This combination is not recommended for use during pregnancy. Please consult your doctor before using this medicine and advice. 

This combination is not recommended for use while breastfeeding. Please consult your doctor before using this medicine and advice. 

The safety and efficacy of this combination have not been established in children under twelve years of age. Please consult your child’s doctor before using it in such children. 

Be cautious about using this combination in elderly people with liver, kidney, and cardiac diseases. Dosage adjustments may be required. Your doctor will check your history of illnesses, health and current body status and prescribe it accordingly.

Drowsiness and sleepiness may occur up to the intake of this combination. It is best to avoid using machines and driving until you feel normal again. 

No, this tablet is not a steroid. It belongs to the NSAIDs and anti-emetic group of medicines that are used for the treatment and prevention of migraine headaches. 

Terms & Conditions


Available medicines for Naproxen + Domperidone
Naproxzen D 500 Tablet 10
Naproxzen D 500 Tablet 10
Steris Healthcare
Pack of 10 Units
₹58.90
MRP ₹118.00
50.08% OFF
Naxdom 250 Tablet 15
Naxdom 250 Tablet 15
Unimed Technologies Limited
Pack of 15 Units
₹91.20
MRP ₹114.00
20.00% OFF
Domstal Np 500 Tablet 10
Domstal Np 500 Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹64.16
MRP ₹80.20
20.00% OFF
Naproxzen D 250 Tablet 10
Naproxzen D 250 Tablet 10
Steris Healthcare
Pack of 10 Units
₹34.93
MRP ₹70.00
50.10% OFF
Naproxen D Tablet 10
Naproxen D Tablet 10
Ausmed Healthcare
Pack of 10 Units
₹95.31
MRP ₹191.00
50.10% OFF
Napra D 250 Tablet 10
Napra D 250 Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹62.00
MRP ₹77.50
20.00% OFF
Naxdom 500 Tablet 15
Naxdom 500 Tablet 15
Sun Pharma Laboratories Ltd.
Pack of 15 Units
₹124.80
MRP ₹156.00
20.00% OFF
Napra D 500 Tablet 10
Napra D 500 Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹94.00
MRP ₹117.50
20.00% OFF

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