Last updated on : 01 Dec, 2025
Read time : 9 min
Arthritis is a general term for joint diseases characterized by inflammation, which causes pain, swelling, and restricted movement. The three most common types are:
While medication remains the cornerstone of treatment, lifestyle management—including maintaining a healthy weight, regular, appropriate physical activity, and making informed dietary choices- plays a critical supportive role in managing symptoms and potentially slowing disease progression [2]. Certain foods contain compounds that can either promote or reduce systemic inflammation, directly influencing the frequency and severity of arthritis symptoms, particularly joint pain and swelling.
Purines are naturally occurring chemical compounds found in many foods. When purines are metabolized by the body, they break down into uric acid.
People with gout must be particularly mindful of their intake of high-purine foods, as elevated uric acid levels can trigger painful gout attacks. Limiting these foods can help maintain uric acid levels within a safe range [3].
Foods that are typically high in purines include:
Important Note: The link between purine-rich vegetables (like spinach and cauliflower) and gout flare-ups is not as strong as the link with purine-rich meats and seafood, and they do not need to be eliminated [4].
Excessive consumption of refined sugars, often found in packaged sweets, sodas, and fruit juices, can lead to a rapid increase in blood sugar. This effect may contribute to the production of pro-inflammatory messengers called cytokines in the body [5].
Furthermore, foods high in both refined sugars and unhealthy fats contribute to weight gain. Obesity is a significant risk factor, especially for osteoarthritis (OA) of the knees, because:
Therefore, reducing the intake of “empty calorie” foods—such as full-sugar sodas, pastries, white rice, and excessive amounts of red meat or full-fat dairy—is a key strategy for weight management and overall reduction of systemic inflammation.
Foods cooked using high-heat methods, such as grilling, frying, and broiling, often contain elevated levels of compounds known as Advanced Glycation End products (AGEs).
Research suggests that high levels of AGEs in the body can promote oxidative stress and chronic inflammation, which are central to the development and progression of arthritis [8].
It is advisable to favour cooking methods that minimize AGE formation, such as boiling, poaching, steaming, or slow cooking.
The majority of people with arthritis do not need to eliminate gluten.
However, some individuals with arthritis, particularly RA, may also have Celiac Disease or Non-Celiac Gluten Sensitivity (NCGS) [9]. In these cases, consuming gluten triggers an immune response leading to widespread systemic inflammation, which can exacerbate existing joint pain and swelling.
If you suspect gluten is a trigger, it is crucial to consult a doctor or a qualified dietitian. They can accurately test for Celiac Disease or NCGS before you eliminate gluten, ensuring you maintain a nutritionally complete diet.
Butter and certain vegetable oils are high in saturated fats, and commercially fried foods and many packaged snacks contain unhealthy Trans fats. Both types of fat are known to promote systemic inflammation.
The American Heart Association recommends limiting saturated fat to less than 6% of daily calories and avoiding Trans fats completely [10].
Healthier Alternatives: It is beneficial to replace saturated fats with anti-inflammatory unsaturated fats, such as the Omega-3 fatty acids found in olive oil, flaxseeds, avocados, and certain nuts.
Alcohol can negatively impact arthritis in several ways, and the effect is often dose-dependent:
A balanced approach is vital. It is generally advised for those with inflammatory arthritis to limit alcohol intake and strictly follow their clinician’s advice regarding consumption, especially if on prescription medication.
Processed foods, including many pre-packaged meals, fast food, and certain snack items, are often high in several ingredients that can contribute to inflammation:
The goal is to move away from “ultra-processed” foods towards a diet rich in whole, unprocessed ingredients.
Conclusion
Managing arthritis successfully involves a comprehensive, multi-faceted approach where medication, physical activity, and informed dietary choices are equally important. Limiting or modifying the intake of high-purine meats, excessive calories, refined sugars, high-AGE foods, alcohol, and ultra-processed items can effectively help reduce systemic inflammation, ease joint pain, and support joint integrity.
Always individualize these adjustments with professional guidance from a doctor or registered dietitian to account for your specific diagnosis, age, comorbidities, and personal preferences. This ensures the formation of sustainable habits that enhance long-term quality of life and protect joint health.
Yes, for many individuals, diet is a powerful adjunct therapy. Avoiding known trigger foods (like purine-rich items for gout) and shifting to an anti-inflammatory diet (rich in Omega-3s, fruits, and vegetables) lowers systemic inflammation, which can translate to less swelling and discomfort over time [12]. Diet works best alongside prescribed medication and appropriate regular exercise for lasting relief.
No, total elimination is rarely necessary or recommended. While very high-purine foods (like organ meats) should be largely avoided, moderate consumption of lean poultry or certain healthy fish may be acceptable. The focus should be on reducing overall load and eliminating the strongest triggers.
Only if a person with OA also has a diagnosed coeliac disease or non-coeliac gluten sensitivity. For the majority of OA patients, whole-grain gluten foods are a healthy source of fibre and can remain part of an arthritis-friendly plan.
This is highly individual, but caution is paramount. Even moderate drinking can raise uric acid and interfere with certain medications. For inflammatory conditions, the safest advice is often to limit consumption significantly or avoid it entirely during flare-ups. A specific limit should be discussed directly with your rheumatologist or prescribing physician.
[1] Dey, M., Cutolo, M., & Nikiphorou, E. (2020). Beverages in rheumatoid arthritis: What to prefer or to avoid. Nutrients, 12(10), 3155. https://doi.org/10.3390/nu12103155
[2] Tedeschi, S. K., Frits, M., Cui, J., Zhang, Z. Z., Mahmoud, T., Iannaccone, C., Lin, T.-C., Yoshida, K., Weinblatt, M. E., Shadick, N. A., & Solomon, D. H. (2017). Diet and rheumatoid arthritis symptoms: Survey results from a rheumatoid arthritis registry. Arthritis Care & Research, 69(12), 1920–1925. https://doi.org/10.1002/acr.23225
[3] Singh, J. A., Reddy, S. G., & Kundukulam, K. S. (2011). Risk factors for gout and prevention: a systematic review of the literature. Current Opinion in Rheumatology, 23(2), 192–202. https://doi.org/10.1097/BOR.0b013e3283438e88
[4] Choi, H. K., Liu, S., & Curhan, G. (2005). Intake of purine-rich foods, protein, and dairy products and risk of gout. The New England Journal of Medicine, 355(20), 2097–2106. https://doi.org/10.1056/NEJMoa044435
[5] Ma, Q., Breyer, A., & Lee, W. (2018). The impact of sugar-sweetened beverages on inflammation: a systematic review of clinical trials. Journal of Clinical Endocrinology & Metabolism, 103(8), 3020–3030. https://doi.org/10.1210/jc.2018-00494
[6] Messier, S. P., Mihalko, S. L., Legault, L., Miller, G. D., Nicklas, B. J., DeVita, P., Beavers, D. P., Hunter, D. J., Lyles, M. F., Eckstein, F., & Williamson, D. S. (2005). Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes in overweight and obese adults with knee osteoarthritis. JAMA, 294(10), 1266–1273. https://doi.org/10.1001/jama.294.10.1266
[7] Scotece, M., Conde, J., Gómez, R., López, V., Gómez-Reino, J. J., Lago, F., Gualillo, O., & Mobasheri, A. (2014). Adipokines and cellular crosstalk in the joint: current knowledge and future therapeutic implications. Seminars in Cell & Developmental Biology, 27, 91–101. https://doi.org/10.1016/j.semcdb.2014.01.002
[8] Vlassara, H., & Uribarri, J. (2014). Advanced glycation end products (AGE) and diabetes. Clinics in Geriatric Medicine, 30(4), 599–612. https://doi.org/10.1016/j.cger.2014.06.007
[9] Pellegrino, R., Fichera, E., & Marletta, D. (2023). Diet and Rheumatoid Arthritis: The Relevance of Food Processing. Nutrients, 15(8), 1858. https://doi.org/10.3390/nu15081858
[10] Lichtenstein, A. H., Mozaffarian, D., P. J., V. L., B., P. S., P., G. L., C., L. C., R. W., S., P. M. and W., S. (2021). 2021 AHA/ACC/AHA Joint Statement on the Dietary Guidelines for Americans. Circulation, 144(11), e163–e178. https://doi.org/10.1161/CIR.0000000000001031
[11] Cutolo, M., Nikiphorou, E., & Dey, M. (2021). Alcohol and rheumatoid arthritis: a systematic review. Rheumatology International, 41(3), 441–448. https://doi.org/10.1007/s00296-020-04663-1
[12] Gioia, C., Monti, S., Benucci, M., Li Gobbi, N., Bazzichi, L., & Pelosini, I. (2020). The role of diet in the management of rheumatoid arthritis: a systematic review. Nutrients, 12(5), 1453. https://doi.org/10.3390/nu12051453
Disclaimer
Our healthcare experts have carefully reviewed and compiled the information presented here to ensure accuracy and trustworthiness. It is important to note that this information serves as a general overview of the topic and is for informational purposes only. It is not intended to diagnose, prevent, or cure any health problem. This page does not establish a doctor-patient relationship, nor does it replace the advice or consultation of a registered medical practitioner. We recommend seeking guidance from your registered medical practitioner for any questions or concerns regarding your medical condition.
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