Mefenamic Acid + Paracetamol

Dosage Forms Available

• Mefenamic Acid + Paracetamol can be taken orally (tablet and suspension).

Age And Dose Restrictions

• This combination is intended for adults and children over six months of age. 

Contraindications 

• This combination is contraindicated in patients with a history of hypersensitivity to mefenamic acid or paracetamol, patients with pre-existing asthma, aspirin-sensitive asthma, and during coronary artery bypass graft (CABG) surgery. 

Other Medications To Avoid With This Medicine

• Avoid taking antacids (aluminium hydroxide), antiarrhythmics (digoxin), diuretics (furosemide), anticoagulants (warfarin), immunosuppressive medications (methotrexate), cholesterol-lowering medications (cholestyramine), prokinetic agents (metoclopramide and domperidone), anticonvulsants (carbamazepine), antihypertensives (amlodipine), antibiotics (amikacin, tobramycin, gentamicin), and other NSAIDs (aspirin) with this combination. These medications may alter the safety and effectiveness of Mefenamic Acid + Paracetamol.

Overdose And Missed Dose

• Overdose can cause lethargy, drowsiness, nausea, vomiting, and abdominal pain. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
• If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

• Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

• This combination can cause dizziness and drowsiness. It is not recommended to drive, operate machinery, or do other activities requiring mental alertness or coordination after this combination. 

Use In Pregnancy And Lactation

• This combination is not recommended during the third trimester of pregnancy. Caution is advised during 1st and 2nd trimester of pregnancy and breastfeeding.

Caution In Other Conditions

• Caution is advised in older adults and patients with heart conditions, active ulceration/bleeding, chronic inflammation of the gastrointestinal tract and kidney and liver impairment.

Special Dietary And Lifestyle Recommendation

• Avoid alcohol consumption, as it may increase the risk of liver toxicity and adverse side effects.
• Take this combination only for the prescribed duration.
• Maintain a healthy weight. Excess weight can contribute to joint pain and inflammation, so maintaining a healthy weight can reduce these issues.
• Engage in regular, low-impact exercises such as walking, swimming, or cycling to improve flexibility and strengthen muscles.