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Drotaverine + Mefenamic Acid

ANTISPASMODIC / ANALGESIC

Uses of Drotaverine + Mefenamic Acid

  • Drotaverine + Mefenamic Acid is a combination medication used to treat various types of pain, including abdominal pain, muscle pain, migraine headaches, and pain associated with functional bowel disorders.
  •  It is also effective in managing dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain (kidney-related pain), and post-surgical pain. 
  • It is also effective in treating gastrointestinal spasms, providing relief from pain related to various gastrointestinal disorders. 
  • Additionally, this combination may be used to manage tension headaches. Its versatility in addressing different types of pain makes it a common prescription for acute pain relief.

Side effects of Drotaverine + Mefenamic Acid

The side effects of Drotaverine + Mefenamic Acid are:

  • Diarrhoea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Constipation 
  • Indigestion
  • Headache
  • Dizziness
  • Flushing

How Drotaverine + Mefenamic Acid works

  • Drotaverine + Mefenamic Acid is a pain reliever.
  • Drotaverine is a smooth muscle relaxant that helps to relieve spasms by inhibiting an enzyme called phosphodiesterase-4 (PDE-4). This action leads to the relaxation of smooth muscles in various parts of the body, reducing pain and discomfort caused by spasms. 
  • Mefenamic Acid, on the other hand, is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are chemicals in the body responsible for causing inflammation and pain. Together, they provide relief from pain and spasms associated with conditions like menstrual cramps, muscle spasms, and gastrointestinal disorders.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • This combination can be taken orally (tablet).

Age and Dose Restrictions

  •  This combination is intended to be used by adults only.

Contraindications

  •  This combination is contraindicated in patients with a history of hypersensitivity to drotaverine or mefenamic acid, patients with pre-existing asthma, aspirin-sensitive asthma, and during coronary artery bypass graft (CABG) surgery.

Medications to Avoid with This Drug

  • Avoid taking antacids, antiarrhythmics (digoxin), diuretics, anticoagulants (warfarin), immunosuppressive medications (methotrexate), antihypertensives, chemotherapy such as pemetrexed, other NSAIDs (aspirin), muscarinic antagonists (atropine), antiparkinson agents (levopoda), and antidepressants such as diazepam. These medications may alter the safety and effectiveness of this combination.

Overdose and Missed Dose

  • Overdose can cause lethargy, drowsiness, nausea, vomiting, abdominal pain, weakness, dizziness, headache, a drop in blood pressure and sleepiness. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of this combination, take it as soon as you remember, but if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management of Side Effects

  • Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This combination can cause dizziness and drowsiness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this combination. 

Use in Pregnancy and Lactation

  • This combination is not recommended during pregnancy and breastfeeding.

Caution in Other Conditions

  • Caution is advised in older adults and patients with heart conditions, hypertension, hypotension, congestive heart failure and odema, active ulceration/bleeding, inflammation of the gastrointestinal tract and kidney and liver impairment.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol consumption, as it may increase the risk of gastrointestinal irritation and other adverse effects.
  • Take this combination only for the prescribed duration.
  • Engage in regular, low-impact exercises such as walking, swimming, or cycling to improve flexibility and strengthen muscles.
  • Consider incorporating probiotics into your diet to promote a healthy balance of gut bacteria and potentially reduce symptoms.
  • Reduce consumption of caffeine, as these can exacerbate IBS symptoms.

Frequently asked questions

Yes, this combination is a painkiller. This combination helps reduce pain associated with menstrual cramps, kidney stone and inflammation of colon.

This combination typically shows its effects within 30 minutes to an hour after ingestion. However, individual responses may vary. 

This combination is not habit-forming and is generally safe when used as directed.

The use of this combination may impair female fertility and is not recommended in women attempting to conceive.

This combination usually requires a prescription and is not available over the counter.

This combination may relieve pain for up to a few hours. However, the duration of effect of this medication can vary with the individual and the severity of the condition being treated.

This combination is effective in reducing stomach pain associated with menstruation and irritable bowel syndrome. However, its use for stomach pain should only be done when a doctor advises.

Yes, this combination may cause sleepiness when the dosage is exceeded.

Terms & Conditions


Available medicines for DROTAVERINE + MEFENAMIC ACID
Drotikind M Tablet 10
Drotikind M Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
₹84.34
MRP ₹102.85
18.00% OFF
Drofem Tablet 10
Drofem Tablet 10
Fdc Ltd.
Pack of 10 Units
₹58.63
MRP ₹71.50
18.00% OFF
Dvn Plus Tablet 10
Dvn Plus Tablet 10
Overseas Healthcare Pvt Ltd.
Pack of 10 Units
₹170.15
MRP ₹207.50
18.00% OFF
Drotaclear Spas Tablet 10
Drotaclear Spas Tablet 10
Glenmark Pharmaceuticals Ltd.
Pack of 10 Units
₹43.66
MRP ₹87.50
50.10% OFF
Tavera M Tablet 10
Tavera M Tablet 10
Leeford Healthcare
Pack of 10 Units
₹34.93
MRP ₹70.00
50.10% OFF
Ditim Mf Tablet 10
Ditim Mf Tablet 10
Biochem Pharmaceutical Inds
Pack of 10 Units
₹88.87
MRP ₹178.10
50.10% OFF
Drotin M Tablet 10
Drotin M Tablet 10
Walter Bushnell
Pack of 10 Units
₹174.62
MRP ₹212.95
18.00% OFF
Cytospas 80/250 MG Tablet 10
Cytospas 80/250 MG Tablet 10
Cytochem Health Care India Pvt Ltd
Pack of 10 Units
₹29.52
MRP ₹36.00
18.00% OFF

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