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Dicyclomine + Mefenamic Acid

Antispasmodic / Analgesic

Uses of Dicyclomine + Mefenamic Acid

  • Dicyclomine + Mefenamic Acid is mainly used to treat pain in the abdomen and address dysmenorrhoea.

Side effects of Dicyclomine + Mefenamic Acid

  • Nausea and vomiting
  • Diarrhoea
  • Headache
  • Dizziness
  • Constipation

How Dicyclomine + Mefenamic Acid works

  • Dicyclomine is an anticholinergic that acts as an antispasmodic by relaxing the stomach muscles. This relaxation can ease abdominal pain and discomfort, especially related to irritable bowel syndrome (IBS).
  • Mefenamic Acid is an NSAID that inhibits the production of certain chemicals called prostaglandins. These prostaglandins are involved in promoting inflammation, pain, and fever. By reducing their levels, mefenamic acid helps relieve pain and discomfort.
  • This combination provides a dual-action approach. While mefenamic acid targets the inflammatory aspect of pain, dicyclomine helps relax spasms in the gut, reducing abdominal pain and cramps.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • This combination can be taken orally (tablet).

Age and Dose Restrictions

  • This combination is intended to be used by adults and children above 12 years of age.

Contraindications

  • This combination is contraindicated in patients with a history of hypersensitivity to dicyclomine or mefenamic acid, patients having peptic ulcers, bleeding disorders, asthma, glaucoma, myasthenia gravis, high blood pressure, or inflammatory bowel disease.

Other Medications To Avoid With This Medicine

  • Avoid taking ACE inhibitors (benazepril), NSAIDs (aspirin), diuretics (hydrochlorothiazide), antidepressants (lithium), antimetabolites (methotrexate), cardiac glycosides (digoxin), oral hypoglycemic agents (glipizide), antiplatelet agents (clopidogrel), corticosteroids (prednisone), and antiglaucoma agents (latanoprost). These medications may alter the safety and effectiveness of this combination.

Overdose and Missed Dose

  • Overdose can cause lethargy, drowsiness, nausea, headache, blurred vision, dilated pupils, hot and dry skin, dizziness, dryness of the mouth, difficulty in swallowing, vomiting, (upper stomach) epigastric pain, tonic-clonic (grand mal) fits, gastrointestinal bleeding, high blood pressure, acute renal failure, CNS stimulation (increased alertness, attention, energy and physical activity), respiratory depression (slow and ineffective breathing), muscular weakness paralysis and coma. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of this combination, take it as soon as you remember, but if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management of Side Effects

  • Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This medicine can cause dizziness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use in Pregnancy and Lactation

  • This combination is not recommended during pregnancy and breastfeeding.

Caution in Other Conditions

  • Caution is advised in older adults and patients with kidney and liver impairment.

Special Dietary & Lifestyle Recommendation

  • Incorporate regular exercise, including gentle activities like jogging and walking, to keep your muscles stretched and less prone to spasms, tears, or sprains.
  • It is advised to avoid taking alcohol if you are taking this combination.
  • Consider getting massages, as they can help relax tense muscles and alleviate spasms.
  • Be cautious with extreme temperatures. Avoid exposure to very cold or hot environments, which can trigger muscle spasms.
  • Opt for loose-fitting clothing instead of tight garments to prevent muscle constriction.
  • Ensure you get enough rest and good sleep to allow your muscles to recover properly.
  • Apply ice or hot packs to the affected muscles for 15-20 minutes to relieve muscle spasms and discomfort.
  • Drink sufficient water to maintain proper hydration, which is essential for muscle function.

Frequently asked questions

No, this combination is not recommended to be used in pregnancy. 

No, this combination is not recommended to be used during breastfeeding. 

This combination is available as pediatric formulations, which are indicated for children who are aged below twelve years of age. 

This combination should be given with caution in elderly patients as their liver and kidney function might decrease with age and is not advised in elderly who suffer from high blood pressure, peptic ulcers, glaucoma, bleeding disorders, myasthenia gravis, inflammatory bowel disease, liver and kidney impairment.

No, this combination is not recommended for patients with kidney disorders. 

No, this combination is not recommended for patients with liver disorders.

This combination is used to provide relief from the pain of menstrual cramps during the menstrual cycle. It does not affect the menstrual bleeding.

The symptomatic and supportive care is given for the overdose of this combination which includes emesis or use of activated charcoal, and osmotic catharsis.

Terms & Conditions


Available medicines for Dicyclomine + Mefenamic Acid
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