Home/Drugs By Ailments / Chlorpheniramine Maleate + Phenylephrine Hydrochloride

Chlorpheniramine Maleate + Phenylephrine Hydrochloride

COUGH COLD PREPARATION

Uses of Chlorpheniramine Maleate + Phenylephrine Hydrochloride

  • Chlorpheniramine Maleate + Phenylephrine Hydrochloride is used to treat symptoms of the common cold and allergic rhinitis in children. 
  • It helps relieve watery eyes, runny nose, sneezing, and itching of the nose or throat. 
  • Chlorpheniramine Maleate is an antiallergic that alleviates allergy symptoms, while Phenylephrine reduces nasal congestion.

Side effects of Chlorpheniramine Maleate + Phenylephrine Hydrochloride

  • Headache
  • Dry Mouth
  • Upset of stomach
  • Constipation
  • Disturbed Sleep
  • Drowsiness
  • Dizziness

How Chlorpheniramine Maleate + Phenylephrine Hydrochloride works

  • Chlorpheniramine maleate is a type of antihistamine medication that also has anticholinergic properties. Antihistamines work by blocking histamine H1 receptor sites in the body, reducing the effects of histamine. This helps prevent histamine from causing dilation of capillaries and swelling of the respiratory mucosa, alleviating symptoms like congestion and edema.
  • Phenylephrine is a type of oral sympathomimetic amine that works as a nasal decongestant by acting on the nasal mucosa. It has a strong effect on α-receptors after binding, which helps shrink blood vessels in the nasal passages and alleviate congestion. This action primarily occurs through direct interaction with receptors, with a minor contribution from its ability to release norepinephrine. By targeting the underlying cause of nasal congestion, phenylephrine effectively reduces symptoms of a stuffy or congested nose.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Chlorpheniramine Maleate + Phenylephrine Hydrochloride is available for use via oral route (syrup, oral drops).

Age and Dose Restrictions

  • This medicine is meant for adults and children above 6 months of age.

Contraindications

  • This medicine is contraindicated in patients with known allergies to chlorpheniramine maleate+phenylephrine and patients with heart disorders, who have been treated with monoamine oxidase (MAO) inhibitors, with peripheral vascular insufficiency, hyperthyroidism, glaucoma, prostate problems, pheochromocytoma.

Medications to Avoid with This Drug

  • It might interact with other medications like anti-allergic drugs (such as cetirizine, fluticasone, and diphenhydramine), blood thinners (like aspirin), cough suppressants (such as dextromethorphan), anti-hypertensive drugs (like atorvastatin), anti-asthma medications (such as albuterol), antacids (like pantoprazole), and antidepressants (including isocarboxazid, rasagiline, linezolid, and tranylcypromine).

Overdose and Missed Dose

  • An overdose of this medication may cause ataxia, excitement, tremors, psychosis, hallucinations, and convulsions. If you observe this symptom, inform your doctor and follow the advice accordingly.
  • If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use In Driving And Operating Machinery

  • This medication will impair your ability to drive or operate machinery as it causes drowsiness.

Use in Pregnancy and Lactation

  • This medicine is not recommended in pregnancy and breastfeeding.

Caution in Other Conditions

  • Patients with renal or hepatic conditions should exercise caution when taking this medicine.

Special Dietary & Lifestyle Recommendation

  • Hydration is essential for those with a cough or cold. Drinking liquids at room temperature can help ease symptoms like coughing, runny nose, and sneezing.
  • Stress can weaken the immune system and increase the risk of illness. To reduce stress, try exercising regularly, meditating, practising deep breathing, and using progressive muscle relaxation techniques.
  • Aim to get at least 8 hours of sleep each night to stay healthy and energised.
  • Avoid contact with known allergens like pollen and dust to prevent allergic reactions. Be mindful of specific food items that may trigger allergies for you.
  • Maintain personal hygiene and keep your surroundings clean to reduce the risk of illness and promote overall well-being.

Frequently asked questions

This medicine's onset of action may require a few hours for full efficacy to be realised.

If you're allergic to this medicine, don't take it. Seek medical help right away if you have any allergic reactions. Also, exercise caution while taking this combination if you have kidney and liver problems.

Please do not discontinue Chlorpheniramine Maleate + Phenylephrine Hydrochloride without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.

Patients with renal or hepatic conditions should exercise caution when taking this medicine.

This medication does not affect your fertility, however, discuss it with your doctor before taking it

Terms & Conditions


Chlorpheniramine Maleate + Phenylephrine Hydrochloride in other salts

CHLORPHENIRAMINE MALEATECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + CODEINEAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + SODIUM CITRATEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESINCAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + MENTHOLCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHANCHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLPROPANOLAMINECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINBROMHEXINE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINCHLORPHENIRAMINE MALEATE + DIETHYLCARBAMAZINEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE
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