Chlorpheniramine Maleate + Dextromethorphan + Phenylephrine Hydrochloride is a combination medicine used for temporary relief of symptoms associated with the common cold, flu, allergies, and hay fever.
This combination is commonly used for:
• Common cold and flu: Relieves sneezing, a runny nose, and body aches.
• Allergies and hay fever: Eases itching, watery eyes, and nasal symptoms caused by allergens.
• Dry cough: Reduces the urge to cough caused by throat and airway irritation.
• Nasal and sinus congestion: Relieves a blocked or stuffy nose and sinus pressure.
Drowsiness
Dizziness
Headache
Dry mouth, nose, and throat
Nausea and vomiting
Chlorpheniramine Maleate + Dextromethorphan + Phenylephrine Hydrochloride combines three medicines to relieve several cold and allergy symptoms together.
Chlorpheniramine Maleate is an antihistamine. It blocks histamine, a natural chemical that causes allergic symptoms such as sneezing, itching, and watery eyes.
Dextromethorphan is a cough suppressant. It acts on the cough centre in the brain to reduce the urge to cough.
Phenylephrine Hydrochloride is a decongestant. It narrows the small blood vessels in the nasal passages, reducing swelling and congestion.
Together, these three ingredients relieve symptoms such as a runny nose, sneezing, itchy or watery eyes, itchy throat, and coughing associated with colds, flu, and allergies.

Doctor of Medicine

BAMS, FMC, MD Resident
Chlorpheniramine Maleate + Dextromethorphan + Phenylephrine Hydrochloride is available as an oral solution or syrup, oral suspension, tablets, capsules, for use via the oral route.
This combination of medicines is meant for adults and children aged 12 years and above.
The use of Chlorpheniramine Maleate + Dextromethorphan + Phenylephrine Hydrochloride is contraindicated in patients with known hypersensitivity or allergy to any of its ingredients.
It is also contraindicated in patients with severe hypertension (high blood pressure) or severe coronary artery disease (a medical condition where the blood vessels supplying the heart muscles are narrowed).
This combination may interact with MAO inhibitors (such as selegiline and rasagiline) and antidepressants (such as fluoxetine and duloxetine).
Taking more than the prescribed dose may cause drowsiness, a rapid heartbeat, hallucinations, and seizures. Seek medical attention immediately if an overdose is suspected.
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For dry mouth, try to keep yourself hydrated by drinking plenty of water.
For dizziness or drowsiness, try to rest and avoid activities requiring alertness until you feel better.
Chlorpheniramine Maleate + Dextromethorphan + Phenylephrine Hydrochloride may cause drowsiness or dizziness. If you experience these side effects, avoid driving or operating heavy machinery.
It is advised to consult your doctor if you are pregnant, planning to conceive, or breastfeeding.
Patients with high blood pressure, heart disease, diabetes, liver or kidney disease, thyroid disorder, and those with difficulty urinating due to an enlarged prostate should exercise caution while using this medication.
Try to maintain a balanced diet and regular sleep schedule as a poor diet and lack of sleep can exacerbate some symptoms like fatigue and irritability.
Try to avoid exposure to allergens (things you're allergic to) as they can exacerbate your symptoms. This might include dust mites, animal dander, mould, pollen, and certain foods.
Frequently asked questions
No, Chlorpheniramine Maleate + Dextromethorphan + Phenylephrine Hydrochloride is not a steroid. It is a combination medicine used to relieve symptoms associated with the common cold, flu, allergies, hay fever, and upper respiratory tract ailments.
The speed of effect can vary among individuals and depends on factors such as the severity of symptoms and the individual's overall health condition. However, in general, you should start experiencing symptom relief within a few minutes to an hour after taking this medication.
Please check the product label or consult your doctor before taking this medicine if you are lactose intolerant. Some formulations may contain lactose.
Common side effects of this medication include drowsiness and nervousness. If you experience mood swings or any other unusual emotional reactions while taking this medication, you should consult with your doctor immediately.
Yes, this combination medicine is used to relieve symptoms of allergies as well as common cold and flu symptoms. This includes relieving itchy, watery eyes and runny nose which are common in allergies.
The best time to take this medication will depend on your specific symptoms and your doctor's advice.
The three active ingredients in this combination work in different ways and may start working at different times after being taken. Always follow the instructions provided by your doctor or pharmacist.
Chlorpheniramine Maleate + Dextromethorphan + Phenylephrine Hydrochloride in other salts

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