Home/Drugs By Ailments / Chlorpheniramine Maleate + Phenylephrine

Chlorpheniramine Maleate + Phenylephrine

COLD PREPARATION

Uses of Chlorpheniramine Maleate + Phenylephrine

Chlorpheniramine Maleate + Phenylephrine is used to alleviate symptoms associated with the common cold and allergic rhinitis.

Side effects of Chlorpheniramine Maleate + Phenylephrine

  • Headache
  • Dry mouth
  • Stomach upset
  • Drowsiness
  • Dizziness

How Chlorpheniramine Maleate + Phenylephrine works

  • Chlorpheniramine maleate is an antihistamine medication that acts as an H1 receptor antagonist and exhibits anticholinergic activity. Antihistamines work by competitively (reversibly) blocking histamine H1 receptor sites on tissues, thereby reducing or eliminating the effects of histamine in the body. Chlorpheniramine maleate explicitly prevents the dilation of capillaries and the development of respiratory mucosa oedema caused by released histamine.
  • Phenylephrine is an orally active sympathomimetic amine that functions as a decongestant by acting on the nasal mucosa. Nasal congestion, often associated with dilated blood vessels, is addressed by Phenylephrine's ability to constrict these vessels within the nasal passages, thereby reducing congestion.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Chlorpheniramine Maleate + Phenylephrine is available for use via the oral route (tablet and syrup).

Age and Dose Restrictions

  • This medicine is meant for adults and children above six months of age.

Contraindications

  • The medication should not be used in individuals with the following conditions: known hypersensitivity to phenylephrine, chlorpheniramine maleate; those who have recently been treated with monoamine oxidase (MAO) inhibitors within the last 14 days; patients currently receiving other sympathomimetic drugs; individuals with cardiovascular disorders; those experiencing peripheral vascular insufficiency; patients diagnosed with hyperthyroidism or glaucoma; individuals with prostate issues, including hypertrophy; and those with pheochromocytoma. It is essential to avoid using this combination in these cases and seek alternative treatments under the guidance of a doctor.

Medications to Avoid with This Drug

  • It is advised against using certain medications, including antihistamines such as cetirizine, fluticasone, and diphenhydramine, beta-Blockers and Other antihypertensives like debrisoquine, guanethidine, reserpine, and methyldopa, tricyclic antidepressants like amitriptyline, ergot alkaloids like ergotamine and methylsergide, alcohol, hypnotics, anxiolytics, sedatives, opioid analgesics, and neuroleptics. Prior to taking any prescription or over-the-counter medicines, it is imperative to consult your doctor.

Overdose and Missed Dose

  • An overdose of this medication may cause symptoms like confusion, decreased heart rate, and high blood pressure. If you observe these symptoms, inform your doctor and follow the advice accordingly.
  • If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use In Driving And Operating Machinery

  • This combination can cause drowsiness, blurred vision, and dizziness. Avoid activities that require complete mental alertness, like driving and operating heavy machinery.

Use in Pregnancy and Lactation

  • This combination is not recommended for use in pregnancy and breastfeeding.

Caution in Other Conditions

  • Use Chlorpheniramine Maleate + Phenylephrine with caution in patients with hypertension, diabetes mellitus, heart disease (angina), peripheral vascular disease, increased intraocular pressure, hyperthyroidism, or prostatic hypertrophy. Avoid combining with other sympathomimetics to prevent potential adverse effects such as insomnia, nervousness, hyperpyrexia, tremors, and epileptiform convulsions.

Special Dietary & Lifestyle Recommendation

  • Ensuring adequate hydration is crucial for individuals experiencing a cough or cold. Consuming fluids at room temperature can help ease coughing, runny nose, and sneezing.
  • Stress can compromise the immune system, increasing susceptibility to illness. Regular exercise, meditation, deep breathing exercises, and progressive muscle relaxation methods can help alleviate stress and support immune function.
  • Maintaining a minimum of eight hours of sleep per night contributes to overall fitness and well-being.
  • To reduce the risk of allergic symptoms, it is advisable to minimise exposure to known allergens, such as pollen and dust. Additionally, individuals should be cautious with specific food items that trigger allergies.

Frequently asked questions

This medicine's onset of action may require a few hours for full efficacy to be realised.

Avoid Chlorpheniramine Maleate + Phenylephrine if you exhibit any allergic reactions (hypersensitivity) to its constituents. Prompt consultation with a doctor is advised.

Please refrain from discontinuing Chlorpheniramine Maleate + Phenylephrine without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.

Patients with kidney and liver issues should exercise caution while taking Chlorpheniramine Maleate + Phenylephrine.

Chlorpheniramine Maleate + Phenylephrine is unlikely to affect fertility in men or women. For the most accurate, updated details regarding this, contact your doctor.

Terms & Conditions


Chlorpheniramine Maleate + Phenylephrine in other salts

CHLORPHENIRAMINE MALEATECETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINECPM + DEXTROMETHORPHAN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDEPHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECARBOXY METHYL CELLULOSE + NAPHAZOLINE + PHENYLEPHRINENAPHAZOLINE + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORBUTOL + PHENYLEPHRINE + TROPICAMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + CODEINEAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + SODIUM CITRATEBROMHEXINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + PHENYLEPHRINE + SALBUTAMOLBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESINBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + MENTHOLCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHANAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESIN + PHENYLEPHRINEDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + MENTHOL + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINEBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLPROPANOLAMINECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PHENYLEPHRINEAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINBROMHEXINE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DIETHYLCARBAMAZINEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PHENYLEPHRINE
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