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Linagliptin

Antidiabetic

Uses of Linagliptin

Linagliptin is an oral antidiabetic medicine used to improve blood sugar control in adults with type 2 diabetes.

It is commonly used for:

  • Type 2 diabetes mellitus: Lowers elevated blood glucose levels when combined with diet, exercise, or other diabetes medications.
  • Post-meal blood sugar management: Prevents sharp spikes in blood sugar levels following meals by enhancing natural insulin release.
  • Long-term glycaemic control: Helps maintain stable daily blood sugar levels to reduce the risk of diabetes-related complications.

Side effects of Linagliptin

  • Sore throat
  • Runny or stuffy nose
  • Cough
  • Diarrhea

How Linagliptin works

  • Linagliptin belongs to a class of diabetes medicines called dipeptidyl peptidase-4 (DPP-4) inhibitors.
  • It works by blocking the DPP-4 enzyme, which normally breaks down natural gut hormones called incretins (GLP-1 and GIP). By preventing their breakdown, Linagliptin increases the level of active incretins in the body.
  • These incretin hormones trigger the pancreas to produce more insulin when blood sugar levels are high after meals, while also reducing the amount of sugar released by the liver. This dual action helps maintain normal blood sugar levels without causing low blood sugar when levels are already normal.

Certified content

Written By

docImg
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years

MBBS

Reviewed By

Dr. Mandeep Chadha
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Expert Advice

Dosage Forms Available

  • Linagliptin is available for use via the oral route (tablets).

Age and Dose Restrictions

  • This medicine is meant for use in adults and children above 18 years of age.

Contraindications

  • Linagliptin is CONTRAINDICATED in patients with allergy to metformin, linagliptin, severe renal or hepatic dysfunction, heart problems, and infection.

Other Medications To Avoid With This Medicine

  • The use of certain medications, including heart condition medications (digoxin), diuretics (furosemide), steroids (budesonide), antibiotics (rifampin), anti-epileptic medications (phenytoin, topiramate, lamotrigine), heart-related chest medications (ranolazine), and antidiabetic drugs, including insulin and beta-blockers (such as metoprolol, propranolol, and timolol eye drops for glaucoma), in conjunction with Linagliptin is not recommended. It is crucial to consult with your doctor before using any prescription or over-the-counter medications.

Overdose and Missed Dose

  • Overdose of this medicine can cause lactic acidosis, such as feeling cold or uncomfortable, severe nausea or vomiting, stomach ache, unexplained weight loss, muscular cramps, or rapid breathing. Inform your doctor regarding these effects and follow the advice accordingly.
  • If you forget a dose of this medicine, take it as soon as you remember. But avoid repeating the dose.

Use In Driving And Operating Machinery

  • Linagliptin themselves do not directly impact your ability to drive or operate machinery. However, they may lead to hypoglycemia which can cause dizziness. Taking precautions to prevent low blood sugar while driving or handling machinery is essential.

Use in Pregnancy and Lactation

  • Linagliptin is not recommended in pregnant and breastfeeding women.

Special Dietary & Lifestyle Recommendation

  • Making lifestyle changes, including dietary modifications and regular exercise, is essential when taking Linagliptin to control blood sugar levels properly.
  • After initiating treatment with Linagliptin, it's recommended to have your blood sugar levels reassessed after 15 days and, subsequently, at regular intervals every 3-6 months. This monitoring helps track the progress of the disease and allows for dose adjustments as needed.
  • If hypoglycemia occurs, it's essential to have a quick source of sugar readily available. Carry sugar candies, glucose tablets, or sugary foods and drinks without fat or protein, such as fruit juice, to promptly address low blood sugar episodes.

Frequently asked questions

This medicine may start to work within a few hours, but it may take some time to see the full effects. It's important to continue taking it as your doctor prescribes, even if you start feeling better.

While taking this medicine, be cautious to avoid hypoglycemia (low blood sugar). Avoid taking it if you are allergic to Linagliptin.

Do not stop taking this medicine without consulting your doctor, even if you feel healthy. Abruptly discontinuing this medication can lead to uncontrolled blood sugar levels.

This medicine typically does not affect fertility. However, if you have concerns about fertility and its impact on diabetes management, discuss them with your doctor.

Terms & Conditions


List of medicines for Linagliptin

Linaxa Tablet 10
Linaxa Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹117.74
MRP ₹147.18
20% OFF
Ondero 5Mg Tablet 15
Ondero 5Mg Tablet 15
Lupin Ltd
Pack of 15 Units
₹216.36
MRP ₹270.45
20% OFF
Linatis 5 Tablet 10
Linatis 5 Tablet 10
Nicholas Healthcare Limited
Pack of 10 Units
₹74.53
MRP ₹149.06
50% OFF
Ondero 5Mg Tablet 10
Ondero 5Mg Tablet 10
Lupin Ltd
Pack of 10 Units
₹144.24
MRP ₹180.3
20% OFF
Linares Tablet 10
Linares Tablet 10
Eris Lifesciences Ltd
Pack of 10 Units
₹135.99
MRP ₹169.99
20% OFF
Trajenta 5Mg Tablet 10
Trajenta 5Mg Tablet 10
Boehringer Ingelheim
Pack of 10 Units
₹279
MRP ₹348.75
20% OFF
Juslina 5 Tablet 10
Juslina 5 Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
₹67.43
MRP ₹84.29
20% OFF
Linapil Tablet 10
Linapil Tablet 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹85.48
MRP ₹106.85
20% OFF

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