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Levocetirizine + Montelukast

Antiallergic

Uses of Levocetirizine + Montelukast

Levocetirizine + Montelukast is used to relieve allergy symptoms and help manag breathing difficulties caused by allergic conditions. It is commonly prescribed for allergic rhinitis (hay fever), asthma triggered by allergies, and long-term management of respiratory allergies.

This combination is commonly used for:

  • Allergic rhinitis (hay fever): Relieves a runny nose, nasal congestion, sneezing, and itchy or watery eyes caused by pollen, dust, or pet allergens.
  • Bronchial asthma: Helps prevent asthma symptoms, particularly those triggered by allergens, by reducing airway inflammation and helping keep the airways open.
  • Chronic urticaria (hives): Reduces skin itching, redness, and raised welts associated with allergic skin reactions.
  • Bronchitis linked to allergies: Eases breathing difficulties and airway irritation related to allergic inflammation.
  • Perennial allergic rhinitis: Manages year-round nasal allergy symptoms that persist beyond seasonal changes.

Side effects of Levocetirizine + Montelukast

The  side effects of Levocetirizine + Montelukast are:

  • Diarrhoea
  • Vomiting
  • Dry mouth
  • Headache
  • Nausea

How Levocetirizine + Montelukast works

Levocetirizine + Montelukast works through two separate mechanisms that together provide broader relief from allergic and respiratory symptoms.

  • Levocetirizine is an antihistamine: When you are exposed to an allergen, your body releases a chemical called histamine, which triggers sneezing, a runny nose, itching, and watery eyes. Levocetirizine blocks the histamine H1 receptors, preventing histamine from acting on the body and reducing these allergy symptoms.
  • Montelukast is a leukotriene receptor antagonist: It blocks chemicals called leukotrienes, which the body releases during an allergic reaction. Leukotrienes cause the airways to narrow, increase mucus production, and lead to inflammation. By blocking these chemicals, Montelukast reduces airway swelling and improves breathing.

Together, both medicines complement each other: Levocetirizine addresses symptoms like sneezing and a runny nose, while Montelukast targets deeper airway inflammation. This dual action makes the combination particularly effective for managing allergic rhinitis alongside asthma.

Certified content

Written By

docImg
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years

MBBS

Reviewed By

Dr. Mandeep Chadha
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Expert Advice

Dosage Forms Available

  • Levocetirizine + Montelukast is available for use via the oral route (tablet).

Age and Dose Restrictions

  • This combination is meant for adults and children above 2 years of age.

Contraindications

  • This medication is contraindicated in patients with known allergies to Levocetirizine or Montelukast, who have a history of severe renal impairment and individuals with galactose intolerance.

Medications to Avoid with This Drug

  • It's advisable to avoid using medicines used for the management of epilepsy ( phenobarbital), tuberculosis (rifampin), chronic obstructive pulmonary disease (theophylline), and HIV (ritonavir) while taking this combination. Always consult a doctor before using prescription or over-the-counter medications.

Overdose and Missed Dose

  • Taking more than the prescribed dose may cause symptoms such as drowsiness, abdominal pain, headache, excessive thirst, and nausea. In children, an overdose may also cause agitation or restlessness. If you suspect an overdose, stop taking the medicine and seek medical attention immediately.
  • If you miss a dose of Levocetirizine + Montelukast, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for the missed one.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when you discontinue this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use in Driving and Operating Machinery

  • This combination may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this medicine.

Use in Pregnancy and Lactation

  • This combination should not be taken during pregnancy and lactation.

Caution in Other Conditions

  • People with severe kidney issues and galactose intolerance should avoid this combination. Precaution is recommended in those who are on CNS depressants.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol when you are taking this combination.
  • To minimise allergic reactions, it's recommended to avoid known allergens like pollen and dust. Additionally, be cautious with certain food items that can trigger allergies.

Frequently asked questions

Levocetirizine + Montelukast is used to manage allergic rhinitis and allergy-associated respiratory symptoms. It combines an antihistamine (Levocetirizine) to block histamine and an anti-leukotriene (Montelukast) to reduce airway inflammation. This combination helps relieve symptoms such as sneezing, runny nose, and itchy or watery eyes, and may help prevent allergy-related asthma symptoms, but it is not intended for treating acute asthma attacks.

Yes, the use of Levocetirizine + Montelukast causes drowsiness or sleepiness hence avoid driving or operating heavy machinery while on Levocetirizine + Montelukast.

The best time to take Levocetirizine + Montelukast is according to your doctor’s instructions. Follow the recommendations precisely. 

Store Levocetirizine + Montelukast at room temperature below 30°C away from moisture. For disposal, follow the instructions on the package insert or contact your nearest pharmacist.

This combination's onset of action may require a few hours for full efficacy to be realised.

Patients should refrain from activities that demand full mental alertness, like driving or operating machinery while taking Levocetirizine + Montelukast. It's advisable to use caution when consuming alcohol or if you're taking CNS depressants.

Please refrain from discontinuing Levocetirizine + Montelukast without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.

Caution is advised, mainly if there's a history of kidney or liver disorders. Certain patients may require a dosage adjustment of Levocetirizine + Montelukast. It's essential to consult your doctor if you have any concerns or underlying health issues.

There is limited information on the impact of Levocetirizine + Montelukast on fertility in men or women. Consult your doctor for the most accurate details.

Levocetirizine + Montelukast should be taken as your doctor directs. Always follow the instructions and do not overdose.

Terms & Conditions


List of medicines for Levocetirizine + Montelukast

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