Diclofenac + Tramadol is a combination medicine used to relieve moderate to severe pain in adults. It combines an NSAID with an opioid analgesic.
This combination is commonly used for:
• Acute musculoskeletal pain: Relieves pain from muscle, joint, or bone injuries.
• Postoperative pain: Manages moderate to severe pain following surgical procedures.
• Dental pain: Eases pain following dental procedures or dental conditions.
• Osteoarthritis and rheumatoid arthritis flare-ups: Relieves pain and discomfort during disease flare-ups.
Nausea
Vomiting
Dizziness
Drowsiness
Fatigue
Diclofenac + Tramadol works through two separate actions that provide effective relief from moderate to severe pain.
Diclofenac is an NSAID. It blocks the cyclooxygenase (COX) enzyme, reducing the production of prostaglandins, the chemicals responsible for pain, inflammation, and fever.
Tramadol is an opioid pain reliever. It attaches to mu-opioid receptors in the brain and spinal cord, which dulls the sensation of pain. It also inhibits the reuptake of serotonin and noradrenaline, further contributing to pain relief.
Together, the two medicines act on different pain pathways in the body, providing more effective relief than either used alone.

Doctor of Medicine

BAMS, FMC, MD Resident
Diclofenac + Tramadol is available in tablet form for oral administration.
Diclofenac + Tramadol is intended for use by adults.
Diclofenac + Tramadol is contraindicated in individuals with known hypersensitivity to either diclofenac or tramadol.
It is also contraindicated in patients with active gastrointestinal bleeding or peptic ulcer disease.
Diclofenac + Tramadol may interact with other NSAIDs (eg., ibuprofen, naproxen), anticoagulants (eg., warfarin, heparin) and antidepressants (eg., fluoxetine, escitalopram).
If you miss a dose of Diclofenac + Tramadol, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.
Drinking plenty of water can help minimise gastrointestinal side effects such as nausea and constipation.
Resting in a quiet, dark room can help manage headaches.
Diclofenac + Tramadol may impair your ability to drive or operate heavy machinery. Avoid these activities if you experience drowsiness and dizziness after taking this medicine.
Diclofenac + Tramadol is not recommended for use during pregnancy or while breastfeeding. Consult your doctor before taking this medication if you are pregnant or breastfeeding.
Individuals with a history of gastrointestinal disorders, cardiovascular disease, or seizure disorders should exercise caution when taking Diclofenac + Tramadol.
People with impaired kidney or liver function should also consult their doctor before taking this medication.
Adopting a balanced diet can help maintain overall health and wellness. Include a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats in your meals.
Maintain a regular sleep schedule to ensure adequate rest and recovery. Avoid consuming stimulants such as caffeine and alcohol close to bedtime.
Frequently asked questions
Yes, Tramadol, an active ingredient in Diclofenac + Tramadol, is an opioid and can lead to dependence or addiction if not used appropriately. Always use under a doctor's supervision and follow the prescribed dosage.
Diclofenac + Tramadol is not typically associated with interference in hormonal balance. Diclofenac is an NSAID, and Tramadol is an opioid analgesic, both used for pain relief. They generally do not impact hormonal levels or balance.
No, Diclofenac + Tramadol is not a steroid. It is a combination medication comprising an NSAID and an opioid pain reliever.
Yes, one of the side effects of Diclofenac + Tramadol can be drowsiness. Therefore, it can potentially affect sleep patterns. If you experience extreme sleep disturbances, consult your doctor.
Diclofenac + Tramadol is not commonly associated with effects on fertility. Diclofenac is an NSAID and Tramadol is an opioid analgesic; neither is known to have significant impacts on reproductive health. However, long-term use or high doses of these medications should be monitored by a doctor.
The duration for Diclofenac + Tramadol to start working can vary from person to person. Generally, pain relief can be felt within an hour after taking the medicine.
Diclofenac + Tramadol is typically prescribed for short-term use for severe pain. Long-term daily use should only be under the direct supervision of a doctor due to potential side effects and risk of dependency.
Diclofenac + Tramadol in other salts
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