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Chlorpheniramine Maleate + Dextromethorphan

Uses of Chlorpheniramine Maleate + Dextromethorphan

Chlorpheniramine Maleate + Dextromethorphan is a combination of an antihistamine and a cough suppressant used to relieve dry cough with cold or allergy symptoms.
This combination is commonly used for:
• Dry, irritating cough: Suppresses the urge to cough caused by throat irritation or the common cold.
• Common cold symptoms: Relieves sneezing, a runny nose, and watery eyes associated with a cold.
• Allergic symptoms: Eases sneezing, nasal discharge, itching, and watering of the eyes caused by allergens.
• Night-time cough disturbance: May reduce dry cough frequency, although the antihistamine can cause drowsiness.

Side effects of Chlorpheniramine Maleate + Dextromethorphan

  • Drowsiness or dizziness

  • Nausea or vomiting

  • Dry mouth, nose, or throat

  • Blurred vision

  • Constipation

How Chlorpheniramine Maleate + Dextromethorphan works

  • Chlorpheniramine Maleate + Dextromethorphan combines an antihistamine with a cough suppressant to relieve cold and cough symptoms.
  • Chlorpheniramine Maleate blocks histamine, a chemical released by the body during allergic reactions, reducing sneezing, itching, and a runny nose.
  • Dextromethorphan acts on the cough centre in the brain, raising the threshold for triggering a cough and reducing the urge to cough.
  • Together, these two actions provide relief from both the allergic symptoms and the dry cough associated with colds and upper respiratory infections.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 10 years

Doctor of Medicine

Reviewed By

Dr. Meenakshi Maruwada
Dr. Meenakshi MaruwadaMedical Content Writer| 9 years

BDS, PGCAD, GMHE (IIM-B)

Expert Advice

Dosage Forms Available

  • Chlorpheniramine Maleate + Dextromethorphan is available for oral use in the form of tablets, capsules, and chewable tablets.
  • It is also available in liquid formulations that include syrup and suspension, as well as lozenges.

Age and Dose Restrictions

  • Chlorpheniramine Maleate + Dextromethorphan can be administered to adults and children aged 12 years and older.
  • This medication should not be used in children under 6 years of age unless directed by a doctor.

Contraindications

  • This combination is contraindicated in individuals allergic to either chlorpheniramine maleate or dextromethorphan.
  • It is also contraindicated for individuals with severe hypertension or coronary artery disease.

Other Medications to Avoid

  • This combination may interact with monoamine oxidase inhibitors (such as selegiline and phenelzine), sedatives (like diazepam and lorazepam), tranquillizers, sleeping pills, narcotic pain relievers (such as codeine), antidepressants (like fluoxetine and sertraline), and muscle relaxants (like cyclobenzaprine).

Overdose and Missed Dose

  • An overdose of Chlorpheniramine Maleate + Dextromethorphan can lead to severe drowsiness, seizures, or loss of consciousness. If you suspect an overdose, seek immediate medical help.
  • If you miss a dose of this medication, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dry mouth, you can frequently sip water or chew sugarless gum.
  • In case of constipation, try to include more fibre in your diet and drink plenty of water.
  • If this medicine makes you drowsy or dizzy, avoid activities that require mental alertness, such as driving or operating machinery.

Use in Driving and Operating Machinery

  • Chlorpheniramine Maleate + Dextromethorphan may cause drowsiness, dizziness or blurred vision. Avoid driving or operating machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • The use of Chlorpheniramine Maleate + Dextromethorphan during pregnancy or breastfeeding is not recommended unless advised by your doctor.

Caution in Other Conditions

  • Individuals with liver or kidney disease, glaucoma, heart disease, high blood pressure, seizures, diabetes or difficulty urinating due to an enlarged prostate should consult their doctor before taking Chlorpheniramine Maleate + Dextromethorphan.

Special Dietary and Lifestyle Recommendations

  • Maintain adequate hydration by drinking plenty of fluids to help relieve dry mouth and prevent constipation.
  • Try to get enough rest and sleep, which can help manage the symptoms of cold or allergies.
  • Incorporate a healthy diet rich in fruits, vegetables, lean proteins, and whole grains, which can bolster your immune system and help you recover faster.
  • Avoid exposure to known allergens as much as possible.

Frequently asked questions

No, Chlorpheniramine Maleate + Dextromethorphan is not a steroid. It is a combination of an antihistamine and a cough suppressant.

Yes, one of the common side effects of Chlorpheniramine Maleate + Dextromethorphan is drowsiness or dizziness. You are advised not to drive or operate machinery if you experience drowsiness after taking it.

Chlorpheniramine Maleate + Dextromethorphan is intended for short-term use to manage symptoms associated with the common cold, hay fever, or other upper respiratory allergies. Long-term use should be avoided unless directed by your doctor.

If you have an allergic reaction to Chlorpheniramine Maleate + Dextromethorphan, such as itching, rash, swelling, or difficulty breathing, stop using the medicine and immediately consult your doctor.

You should always consult your doctor before taking other medicines with Chlorpheniramine Maleate + Dextromethorphan, as it could lead to increased side effects or medicine interactions.

Chlorpheniramine Maleate + Dextromethorphan should be used with caution in patients with heart disease or high blood pressure. If you have these conditions, please consult your doctor before taking this medicine.

If you have liver or kidney disease, it is important to consult your doctor before taking Chlorpheniramine Maleate + Dextromethorphan, as the dosing may need to be adjusted.

Chlorpheniramine Maleate + Dextromethorphan is commonly used to relieve cough, throat irritation, and allergy symptoms like runny nose or sneezing. Dextromethorphan helps suppress cough, while Chlorpheniramine reduces allergic responses for overall relief.

Terms & Conditions


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