The primary use of Azithromycin + Fluconazole + Ornidazole is to manage mixed bacterial, fungal, and parasitic infections. It belongs to the group of antibacterial, antifungal, and antiprotozoal medicines.
This medication is also effective in managing mixed vaginal infections, certain sexually transmitted infections caused by multiple pathogens, and select cases of mixed skin and soft tissue infections.
Nausea
Vomiting
Diarrhoea
Abdominal pain
Headache
Azithromycin belongs to the antibacterial group of medicines that works by binding to the 50S subunit of the bacterial ribosome, interrupting RNA-dependent protein synthesis in bacteria. This either inhibits bacterial growth or kills them altogether.
Fluconazole is an antifungal agent that stops the fungal cytochrome P450 enzyme 14α-demethylase from working normally. This enzyme is needed for the production of ergosterol, a key component of the fungal cell membrane. Inhibiting the enzyme disrupts ergosterol synthesis, increasing cell membrane permeability and leading to cell death.
Ornidazole is an antiprotozoal agent that targets susceptible protozoa by breaking DNA strands. This action inhibits nucleic acid synthesis, leading to cell death. Additionally, ornidazole is effective against anaerobic bacteria, enhancing its utility in treating various infections.
Doctor of Medicine
BMS, FMC, MD Resident
Azithromycin + Fluconazole + Ornidazole is available in tablet form for oral administration.
This medicine is intended for usage by adults and children above 12 years. However, it is strongly recommended to use this medicine only under the supervision of a certified doctor, who will determine the most appropriate dose based on the patient’s age, weight, and overall health condition.
This medicine is contraindicated in patients with known allergies to any of the components of this medication.
It should not be used in patients with severe liver or kidney disease or in those with cardiac disorders like QT prolongation.
This medicine may interact with CYP3A4 inhibitors (eg., ritonavir), medications metabolized by CYP2C9, CYP2C19 and CYP3A4 (eg., warfarin), CNS depressants (eg., diazepam), and cardiac glycosides (eg., digoxin).
Overdosing on Azithromycin + Fluconazole + Ornidazole could lead to serious effects such as severe nausea, vomiting, abdominal pain, and neurological reactions like headache and dizziness. In case you suspect an overdose, seek immediate medical attention.
If you forget to take a dose, take it as soon as you remember. But if it is time for your next dose, skip the missed dose and continue with a regular dosing regime. Do not double up on the dose to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids may help reduce gastrointestinal side effects like nausea and abdominal pain.
Resting in a quiet and dark room may help manage headaches.
Azithromycin + Fluconazole + Ornidazole may cause dizziness or blurred vision. Therefore, it is advisable not to drive or operate heavy machinery after taking this medication until you know how you respond to it.
Using Azithromycin + Fluconazole + Ornidazole during pregnancy or while breastfeeding should only be considered if the benefits outweigh the potential risks. It is important to consult your doctor for advice before taking this medicine if you are pregnant or breastfeeding.
Patients with kidney disorders, liver problems, heart disease, or neurological conditions should exercise caution when taking Azithromycin + Fluconazole + Ornidazole. Regular monitoring of kidney function and liver function may be required in these patients.
For managing bacterial, fungal, and parasitic infections effectively, maintaining a healthy lifestyle and diet is crucial. This includes eating a balanced diet rich in fruits, vegetables, lean proteins, and whole grains.
Adequate hydration is essential as it helps flush toxins from the body.
Regular physical activity can help boost the immune system and speed up recovery from infections.
Good personal hygiene practices such as regular hand washing can help prevent the spread of infections.
Avoiding crowded places can reduce the risk of infectious diseases.
Frequently asked questions
No, Azithromycin + Fluconazole + Ornidazole is not a steroid. It is a combination of an antibacterial, antifungal, and antiprotozoal medicine used to manage mixed infections.
There is no evidence to suggest that Azithromycin + Fluconazole + Ornidazole interferes with sleep. However, individual responses may vary and if you experience any unusual effects on your sleep pattern, consult your doctor.
There is limited data on the effect of this combination on human fertility. Any concerns about fertility should be discussed with your doctor.
There are no specific diet restrictions while taking this medicine, unless instructed by your doctor. It can be taken with or without food.
Yes, it is safe to take Azithromycin + Fluconazole + Ornidazole daily as directed by your doctor. Dosage adjustments may be necessary in case of renal or hepatic impairment.
The onset of action will vary depending on the condition being managed and individual responses to the medication. Consult your doctor for more information.
The best time to take this medicine will depend on your doctor's instructions. It can be taken with or without food.
Azithromycin + Fluconazole + Ornidazole in other salts
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