Azithromycin + Cefixime is used to manage a variety of bacterial infections of the gastro-intestinal system. It belongs to the class of antibiotics, specifically macrolide and third-generation cephalosporin antibiotics.
Secondary uses include the management of respiratory tract infections, skin and skin structure infections by susceptible strains, uncomplicated urinary tract infections, and certain sexually transmitted infections.
Loose stools
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Indigestion
Azithromycin falls under the category of macrolide antibiotics. It obstructs protein production in bacteria by binding to the 50S ribosomal subunit, a component of the bacterial machinery that synthesises proteins. This prevents the bacteria from growing and multiplying.
Cefixime belongs to the third-generation cephalosporin antibiotic group. It inhibits the formation of the bacterial cell wall by binding to penicillin-binding proteins (PBPs), which play a critical role in the final step of peptidoglycan synthesis in bacterial cell walls. This disrupts the structure of the bacterial cell wall, leading to its rupture and death.
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This combination medicine is available as tablets for oral administration.
This medicine is suitable for both adults and children based on weight.
Azithromycin + Cefixime is contraindicated in patients with known hypersensitivity to azithromycin, cefixime, or any component of the formulations. It is also contraindicated in patients with carnitine deficiency or inborn errors of carnitine metabolism.
This combination may interact with antacids (such as aluminium hydroxide and magnesium hydroxide), anticoagulants (like dabigatran and warfarin), cardiac glycosides (including oleandrin and digoxin), and protease inhibitors (such as ritonavir and nelfinavir).
An overdose of Azithromycin + Cefixime may lead to symptoms such as severe nausea, vomiting, diarrhoea, and abdominal pain. In such cases, seeking immediate medical attention is crucial.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.
To manage nausea or upset stomach related to this medication, it may help to take your doses with food.
In case of diarrhoea, ensure adequate hydration by drinking plenty of water.
Azithromycin + Cefixime may cause dizziness or drowsiness in some individuals. If you experience these symptoms after taking this medicine, it is advisable to avoid driving or operating heavy machinery.
Azithromycin + Cefixime falls into pregnancy category B. It should be used during pregnancy only if needed. Both components are excreted in breast milk; hence, breastfeeding mothers should use this medication only under the advice of a doctor.
Patients with liver or kidney impairment should exercise caution when using Azithromycin + Cefixime due to the potential for altered medicine metabolism and excretion, which might require dose adjustments. Care should also be taken in patients with a history of QT prolongation or other heart-related conditions.
Maintain adequate hydration, especially if gastrointestinal side effects such as diarrhoea occur.
To support overall health during antibiotic treatment, incorporate a balanced diet rich in fruits, vegetables, and whole grains.
Practice good hygiene, like washing hands frequently, to help prevent the spread of infections.
Avoid excessive caffeine intake as it may exacerbate gastrointestinal discomfort.
Frequently asked questions
No, Azithromycin + Cefixime is not a steroid. It is a combination of two antibiotics used to manage bacterial infections.
There is no known evidence that Azithromycin + Cefixime directly affects sleep. However, consult your doctor if you experience sleep disturbances after taking this medicine.
There is currently no evidence indicating that Azithromycin + Cefixime has an impact on fertility. However, you should always discuss any concerns regarding fertility with your doctor.
There are no specific diet restrictions while taking Azithromycin + Cefixime. However, it is recommended to maintain a balanced diet to support overall health.
Azithromycin + Cefixime should be taken exactly as prescribed by your doctor. It should not be taken for longer than prescribed or in larger amounts.
The time it takes for Azithromycin + Cefixime to work can vary depending on the type and severity of the infection being managed.
The best time to take Azithromycin + Cefixime is as advised by your doctor.
Azithromycin + Cefixime in other salts
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