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Phenylephrine

Uses of Phenylephrine

  • The primary use of Phenylephrine is to provide temporary relief from nasal and sinus congestion caused by conditions such as the common cold, hay fever or other upper respiratory allergies. It falls under the category of medications known as nasal decongestants.

Side effects of Phenylephrine

  • Trouble sleeping

  • Dizziness

  • Mild stomach upset

  • Nervousness

  • Increased heart rate

How Phenylephrine works

  • Phenylephrine is a nasal decongestant.

  • It works by stimulating the alpha-adrenergic receptors in the lining of the nose. This causes the blood vessels to narrow, reducing blood flow and decreasing inflammation and swelling in the nasal passages. By reducing the swelling of nasal tissues, Phenylephrine opens up the airways, allows mucus to drain, and facilitates easier breathing.

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Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Phenylephrine is available in various forms, including tablets, liquids, dissolving strips, and chewable tablets for oral administration.

Age and Dose Restrictions

  • This medication is suitable for adults and children; however, the dosage is typically based on age.

Contraindications

  • This medicine is contraindicated in individuals who have known allergies to any of its constituents and in patients who are taking or have recently taken (within the last 14 days) monoamine oxidase inhibitors (MAOIs).

  • Additionally, it should not be taken by patients with high blood pressure, severe heart disease, or narrow-angle glaucoma.

Other Medications to Avoid

  • Phenylephrine can interact with antihypertensives (e.g., beta-blockers like propranolol), monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine), and tricyclic antidepressants (e.g., amitriptyline). It may also interact with other vasoconstrictors (e.g., pseudoephedrine).

Overdose and Missed Dose

  • An overdose of this medicine can lead to a range of symptoms, including headaches, nausea, high blood pressure, slow heart rate, and irregular heartbeats. You might also feel a fullness in your head and tingling in your arms or legs. If you experience any of these symptoms, seek medical help right away.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Avoid doubling the dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Sip water if you experience dry mouth.

  • Lying down in a dark, quiet room can help manage headaches.

  • Avoid beverages that contain caffeine as it can contribute to restlessness.

Use in Driving and Operating Machinery

  • Phenylephrine may cause dizziness or lightheadedness, affecting your ability to drive or operate heavy machinery. Avoid these activities if you feel dizzy or lightheaded after taking this medicine.

Use in Pregnancy and Lactation

  • Pregnant or breastfeeding women should consult their doctor before using Phenylephrine.

Caution in Other Conditions

Caution should be exercised when Phenylephrine is used by patients with certain health conditions, such as high blood pressure, heart disease, diabetes, thyroid disorders, an enlarged prostate, and narrow-angle glaucoma.

Special Dietary and Lifestyle Recommendations

  • To manage allergies, it can help to avoid known allergens and irritants.

  • Using a humidifier can help keep nasal and sinus passages moist, reducing congestion.

  • Regular handwashing can prevent the spread of viruses that cause the common cold and flu.

  • Adequate hydration and a healthy diet can boost the immune system, helping to prevent respiratory illnesses.

Frequently asked questions

Taking too much of this medicine can lead to a range of symptoms, including headaches, nausea, high blood pressure, slow heart rate, and irregular heartbeats. You might also feel a fullness in your head and tingling in your arms or legs. If you experience any of these symptoms, seek medical help right away.

In some people, Phenylephrine may cause nervousness or restlessness, which could potentially affect mood. If you notice any such changes while taking this medication, inform your doctor promptly.

Although some natural substances like peppermint and eucalyptus oil are believed to have decongestant properties, their effectiveness varies and they cannot replace a course of treatment with Phenylephrine. Always consult your doctor before trying any alternatives.

The vegan status of a medication depends on its inactive ingredients and the manufacturing process, both of which can vary between different brands and forms of Phenylephrine. Check the product packaging for information or ask your pharmacist to confirm whether a particular product is suitable for vegans.

If you are allergic to pseudoephedrine, you may also be allergic to Phenylephrine as they belong to the same class of medicines called nasal decongestants. Always inform your doctor about all your allergies before starting a new medication.

There are no known food interactions with Phenylephrine, but it is always best to check with your doctor before making any major dietary changes while on medication.

Phenylephrine should not be used with monoamine oxidase inhibitors (MAOIs) as it can lead to dangerous interactions. Consult your doctor for more information.

Terms & Conditions


Phenylephrine in other salts

CETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINECPM + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECARBOXY METHYL CELLULOSE + NAPHAZOLINE + PHENYLEPHRINENAPHAZOLINE + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORBUTOL + PHENYLEPHRINE + TROPICAMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + PHENYLEPHRINE + SALBUTAMOLBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESIN + PHENYLEPHRINEDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + MENTHOL + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINEBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PHENYLEPHRINECAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PHENYLEPHRINE
Available medicines for PHENYLEPHRINE
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