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Ofloxacin + Metronidazole

ANTIBIOTIC

Uses of Ofloxacin + Metronidazole

  • Ofloxacin + Metronidazole is used to treat diarrhoea caused by mixed infection.

Side effects of Ofloxacin + Metronidazole

  • Low blood sugar 
  • Disturbance in attention
  • Disorientation
  • Agitation
  • Nervousness 

How Ofloxacin + Metronidazole works

  • Ofloxacin is a fluoroquinolone antibiotic that inhibits the bacterial enzyme DNA gyrase. This enzyme is essential for DNA replication and repair. By interfering with this process, ofloxacin disrupts bacterial DNA synthesis and inhibits bacterial growth, making it effective against a broad spectrum of bacteria.
  • Metronidazole is an antimicrobial agent that undergoes chemical changes inside bacterial and protozoa cells, generating some compounds. These compounds interfere with DNA replication and damage the genetic material of the microorganisms. As a result, ornidazole is effective against bacteria and protozoa. 

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available 

  • Ofloxacin + Metronidazole can be taken orally (suspension).

Age And Dose Restrictions

  • It can be used by adults above 18 years of age.

Contraindications 

  • It is contraindicated in patients with a history of hypersensitivity to ofloxacin or metronidazole.

Other Medications To Avoid With This Medicine 

  • Avoid taking nutritional supplements, anti-inflammatory medications (theophylline, fenbufen), uricosurics (probenecid), antiarrhythmics (quinidine), antidepressants (sertraline) and anticoagulants (warfarin) with Ofloxacin + Metronidazole. These medications may alter the safety and effectiveness of Ofloxacin + Metronidazole.

Overdose And Missed Dose

  • If you take an overdose of this combination by accident and experience worsening of any of the symptoms, please consult your doctor. It is advised to adhere to the prescribed dose.
  • If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • The side effects resolve after the combination is discontinued. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • Caution is advised in pregnant and breastfeeding women.

Caution In Other Conditions

  • Caution should be taken in older patients especially with kidney dysfunction, liver impairment, heart problems, and patients on corticosteroids.

Special Dietary And Lifestyle Recommendation

  • Make sure you drink plenty of water or other fluids every day.
  • Exercise regularly for the best physical and mental health.
  • Take a balanced diet to nourish the body and the brain. 
  • Maintain proper hygiene to avoid bacterial infections.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.
  • Antibiotics can alter the useful bacteria in the stomach, which can cause indigestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

Frequently asked questions

This combination is used as long as the doctor prescribes it. The duration of the treatment depends upon the severity of the disease, the individual's condition and the patient's response towards the treatment. 

This combination comprises antifungal and antibacterial medications.

Yes, this combination is good for bacterial infections. 

This combination takes more than 2-4 days to show the complete effect. The immediate effect of the medicine is seen within 1-2 hours. However, the response varies from one individual to another individual.

Terms & Conditions


Available medicines for OFLOXACIN + METRONIDAZOLE
Sorry we currently were not able to find medicines related to OFLOXACIN + METRONIDAZOLE.

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