Home/Drugs By Ailments / Ofloxacin + Metronidazole

Ofloxacin + Metronidazole

Antibiotic

Uses of Ofloxacin + Metronidazole

  • Ofloxacin + Metronidazole is a combination medication used to treat a variety of bacterial and parasitic infections, including diarrhea, dysentery, pelvic inflammatory disease (PID), and bacterial vaginosis.
  • Ofloxacin is an antibiotic that fights bacteria, and Metronidazole works against bacteria and amoeba. Together, they make a strong combination to treat infections caused by both bacteria and amoeba.

Side effects of Ofloxacin + Metronidazole

  • Low blood sugar 
  • Disturbance in attention
  • Disorientation
  • Agitation
  • Nervousness 

How Ofloxacin + Metronidazole works

  • Ofloxacin is an antibiotic that works by inhibiting an enzyme called DNA gyrase, which is essential for bacteria to replicate their DNA. Without functional DNA gyrase, bacteria cannot reproduce and the infection is cleared.
  • Metronidazole acts in several ways against bacteria and parasites. It disrupts their DNA replication and may also damage their cell membranes.
  • When used together, Ofloxacin + Metronidazole provide a broader spectrum of activity by targeting both bacteria and parasites.
  • Ofloxacin primarily targets bacteria, while Metronidazole tackles both bacteria and parasites.

Certified content

Written By

docImg
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Reviewed By

Dr. Sachin Singh
Dr. Sachin Singh Medical Team Lead & Reviewer| 7 years

MBBS

Expert Advice

Dosage Forms Available 

  • Ofloxacin + Metronidazole can be taken orally (suspension).

Age And Dose Restrictions

  • It can be used by adults above 18 years of age.

Contraindications 

  • It is contraindicated in patients with a history of hypersensitivity to ofloxacin or metronidazole.

Other Medications To Avoid With This Medicine 

  • Avoid taking nutritional supplements, anti-inflammatory medications (theophylline, fenbufen), uricosurics (probenecid), antiarrhythmics (quinidine), antidepressants (sertraline) and anticoagulants (warfarin) with Ofloxacin + Metronidazole. These medications may alter the safety and effectiveness of Ofloxacin + Metronidazole.

Overdose And Missed Dose

  • If you take an overdose of this combination by accident and experience worsening of any of the symptoms, please consult your doctor. It is advised to adhere to the prescribed dose.
  • If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • The side effects resolve after the combination is discontinued. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • Caution is advised in pregnant and breastfeeding women.

Caution In Other Conditions

  • Caution should be taken in older patients especially with kidney dysfunction, liver impairment, heart problems, and patients on corticosteroids.

Special Dietary And Lifestyle Recommendation

  • Make sure you drink plenty of water or other fluids every day.
  • Exercise regularly for the best physical and mental health.
  • Take a balanced diet to nourish the body and the brain. 
  • Maintain proper hygiene to avoid bacterial infections.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.
  • Antibiotics can alter the useful bacteria in the stomach, which can cause indigestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

Frequently asked questions

Ofloxacin + Metronidazole is used to treat bacterial and parasitic infections in the gastrointestinal and genitourinary tracts. Ofloxacin targets bacterial infections, while Metronidazole is effective against anaerobic bacteria and parasites. This combination is commonly prescribed for conditions like diarrhea, dysentery, bacterial vaginosis, pelvic infections, and certain urinary tract infections, helping clear infections and relieve symptoms.

This combination comprises antifungal and antibacterial medications.

Yes, this combination is good for bacterial infections. 

This combination takes more than 2-4 days to show the complete effect. The immediate effect of the medicine is seen within 1-2 hours. However, the response varies from one individual to another individual.

Yes, the use of Ofloxacin + Metronidazole can cause diarrhoea as a side effect due to its impact on gut bacteria.

Ofloxacin + Metronidazole is  not classified as a very strong antibiotic, but it’s effective against certain infections.  

It is generally safe to take Ofloxacin + Metronidazole for 7-10 days, as prescribed by a doctor.  The duration of use depends on the specific condition and your doctor’s recommendation.

Individuals with a history of allergic reactions to quinolones or nitroimidazoles should avoid using Ofloxacin + Metronidazole. People with irregular heart rhythms or certain allergies should avoid it.

It typically takes a few days to a week for Ofloxacin + Metronidazole to effectively clear an infection, depending on its severity.

Terms & Conditions


List of medicines for Ofloxacin + Metronidazole

O2m Mango Flavour Suspension 60ml
O2m Mango Flavour Suspension 60ml
Medley Pharmaceuticals
Pack of 60 ML
₹62.25
MRP ₹77.81
20% OFF
Oflox Oz Suspension 30ml
Oflox Oz Suspension 30ml
Cipla Ltd.
Pack of 30 ML
₹63.76
MRP ₹79.7
20% OFF
O2 New Mango Flavour Suspension 60ml
O2 New Mango Flavour Suspension 60ml
Medley Pharmaceuticals
Pack of 60 ML
₹66.92
MRP ₹77.81
14% OFF
Nor Metrogyl O Suspension 60ml
Nor Metrogyl O Suspension 60ml
J B Chemicals And Pharmaceuticals Ltd
Pack of 60 ML
₹47.92
MRP ₹59.9
20% OFF
Powergyl Suspension 30ml
Powergyl Suspension 30ml
Cipla Ltd.
Pack of 30 ML
₹63.8
MRP ₹79.75
20% OFF
Oflomac M Suspension 60ml
Oflomac M Suspension 60ml
Macleods Pharmaceuticals Pvt.ltd
Pack of 60 ML
₹54.3
MRP ₹64.64
16% OFF
Ofm Suspension 60ml
Ofm Suspension 60ml
Lekar Pharma Ltd
Pack of 60 ML
₹50.91
MRP ₹59.9
15% OFF

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Registered Office Address

Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346

Grievance Officer

Name: Kishor Kumar

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Playstore
Apple App  Store

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v4.20.1

copyright

2026 - Truemeds | All rights reserved. Our content is for informational purposes only. See additional information.

Trust Certified

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner