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Ofloxacin + Prednisolone

Uses of Ofloxacin + Prednisolone

  • The primary use of Ofloxacin + Prednisolone is to manage bacterial infections where inflammation is also a concern. It belongs to the group of fluoroquinolone antibiotics and corticosteroids.

  • It is also used to manage conditions like tuberculosis, pneumonia, urinary tract infections, allergic reactions, and certain skin conditions involving inflammation.

Side effects of Ofloxacin + Prednisolone

  • Nausea and vomiting

  • Diarrhoea

  • Abdominal pain

  • Headache

  • Skin rash

How Ofloxacin + Prednisolone works

  • Ofloxacin + Prednisolone is a combined antibiotic and corticosteroid medication.

  • Ofloxacin, an antibiotic from the fluoroquinolone group, works by blocking the action of two key enzymes (DNA gyrase and topoisomerase IV) in bacteria. This stops the bacteria from multiplying and leads to their death, thus managing the bacterial infection.

  • Prednisolone, a synthetic glucocorticoid, works by suppressing the production of inflammatory mediators in the body. It attaches to glucocorticoid receptors and modifies gene activity, producing various anti-inflammatory and immunosuppressive effects, which manage inflammation in various conditions.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ofloxacin + Prednisolone is available for use in the form of oral tablets.

Age and Dose Restrictions

  • This combination medicine is intended for use by adults and adolescents above the age of 16 years old.

Contraindications

  • Ofloxacin + Prednisolone is contraindicated in individuals with known hypersensitivity to either ofloxacin or prednisolone.

  • It is also contraindicated in patients with viral or fungal infections due to the immunosuppressive action of prednisolone.

Other Medications to Avoid

  • This combination may interact with antacids and supplements containing iron or zinc (such as ferrous sulfate and ferrous gluconate), anticoagulants (such as warfarin) and antibiotics (like rifampicin) and antifungals (such as itraconazole).

Overdose and Missed Dose

  • Overdosing on Ofloxacin + Prednisolone can lead to symptoms such as nausea, vomiting, dizziness, confusion, hallucinations and seizures. In case of a suspected overdose, seek immediate medical attention.

  • If you miss a dose, take it as soon as you remember. However, if it is near the time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

Management of Side Effects

Most side effects of Ofloxacin + Prednisolone are temporary and may resolve upon discontinuation of the medicine. However, consult your doctor if you notice any severe or persistent side effects.

  • Drinking plenty of water can help manage side effects like dry mouth and constipation.

  • If this medicine upsets your stomach, taking it with food may help.

Use in Driving and Operating Machinery

  • Ofloxacin + Prednisolone may cause dizziness or sleepiness in some people. Avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Ofloxacin + Prednisolone should be used during pregnancy and breastfeeding only if needed, after considering potential risks and benefits.

Caution in Other Conditions

  • Caution should be exercised when using Ofloxacin + Prednisolone in patients with liver or kidney impairment, as these conditions may affect the metabolism and elimination of these medicines.

  • Patients with diabetes or hypertension should also use this combination cautiously due to the potential side effects of prednisolone.

Special Dietary and Lifestyle Recommendations

  • If you are diagnosed with a bacterial infection, ensure to maintain good personal hygiene to prevent the further spread of the bacteria.

  • Adequate rest and hydration can help your body fight off infection effectively.

  • A balanced diet rich in vitamins and minerals can boost your immune system and aid recovery.

  • Regular moderate exercise can also strengthen your immune system.

Frequently asked questions

Exercise is generally safe and beneficial while taking medications unless otherwise specified by your doctor. However, excessive exertion should be avoided as Ofloxacin + Prednisolone can cause tendon inflammation or rupture.

Ofloxacin + Prednisolone can potentially cause insomnia as a side effect in some people. However, this does not occur in everyone and may vary based on the individual's reaction to the medication.

Ofloxacin + Prednisolone is not associated with affecting fertility. If you are planning to conceive, please consult your doctor.

It is safe to take Ofloxacin + Prednisolone daily if prescribed by your doctor. Always follow the prescribed dosage schedule and do not adjust it without consulting your doctor.

The time taken for Ofloxacin + Prednisolone to work would depend on the type and severity of the infection. You should begin to notice an improvement in symptoms within a few days but it is crucial to complete the entire course of medication as prescribed by your doctor.

Ofloxacin + Prednisolone can be taken as per the instructions of your doctor, usually at evenly spaced intervals to maintain a constant level of the medication in your body.

Ofloxacin + Prednisolone tablets may contain lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

Terms & Conditions


Ofloxacin + Prednisolone in other salts

CEFIXIME + OFLOXACINCIPROFLOXACINOFLOXACINOFLOXACIN + METRONIDAZOLEOFLOXACIN + ORNIDAZOLEOFLOXACIN + ORNIDAZOLE + ITRACONAZOLE + CLOBETASOLMETHYL PREDNISOLONEPREDNISOLONECEFPODOXIME + OFLOXACINLEVOFLOXACINCLOBETASOL PROPIONATE + OFLOXACIN + ORNIDAZOLE + TERBINAFINECIPROFLOXACIN + CLOTRIMAZOLE + FLUOCINOLONECIPROFLOXACIN + CLOBETASOL PROPIONATE + METRONIDAZOLE + TERBINAFINEMETHYLPREDNISOLONECLOBETASOL PROPIONATE + ITRACONAZOLE + OFLOXACIN + ORNIDAZOLECLOBETASOL + OFLOXACIN + ORNIDAZOLE + TERBINAFINEDEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINCIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEGATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONECEFIXIME + LACTOBACILLUS + OFLOXACINOFLOXACIN + RACECADOTRILNITAZOXANIDE + OFLOXACINOFLOXACIN + SATRANIDAZOLEOFLOXACIN + ORNIDAZOLE + RACECADOTRILMOXIFLOXACIN + PREDNISOLONEKETOROLAC + OFLOXACINBETAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + PREDNISOLONEBETAMETHASONE + CIPROFLOXACINCIPROFLOXACIN + ORNIDAZOLECIPROFLOXACIN + TINIDAZOLEMETRONIDAZOLE + OFLOXACIN + SIMETHICONEOFLOXACIN + TINIDAZOLECIPROFLOXACIN + METRONIDAZOLELACTOBACILLUS + OFLOXACINAZITHROMYCIN + OFLOXACINAZITHROMYCIN + LEVOFLOXACINCEFPODOXIME PROXETIL + LEVOFLOXACINFLAVOXATE + OFLOXACINBALOFLOXACINAMBROXOL + LEVOFLOXACINLACTOBACILLUS + OFLOXACIN + ORNIDAZOLELACTOBACILLUS + LEVOFLOXACINOFLOXACIN + SODIUM CHLORIDEDEXTROSE + LEVOFLOXACIN
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