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Ofloxacin + Ornidazole

Antibiotic

Uses of Ofloxacin + Ornidazole

  • Ofloxacin + Ornidazole is used to treat diarrhoea caused by mixed infections, gynecological infections, dental infections, ENT infections, and skin and soft tissue infections.

Side effects of Ofloxacin + Ornidazole

  • Nausea and vomiting
  • Abdominal pain
  • Headache
  • Dizziness

How Ofloxacin + Ornidazole works

  • Ofloxacin is a fluoroquinolone antibiotic that inhibits the bacterial enzyme DNA gyrase. This enzyme is essential for DNA replication and repair. By interfering with this process, ofloxacin disrupts bacterial DNA synthesis and inhibits bacterial growth, making it effective against a broad spectrum of bacteria. 
  • Ornidazole is an antimicrobial agent belonging to the nitroimidazole class. It undergoes chemical changes inside bacterial and protozoa cells that generate some compounds. These compounds interfere with DNA replication and damage the genetic material of the microorganisms. As a result, ornidazole is effective against bacteria and protozoa. 

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Ofloxacin + Ornidazole can be taken orally (tablet).

Age And Dose Restrictions

  • This combination is intended for adults and children. 

Contraindications 

  • This combination is contraindicated in patients with a history of hypersensitivity to ofloxacin or ornidazole. It is also contraindicated in patients having central nervous system disease, peripheral nervous system disease, liver and kidney impairment. 

Medications To Avoid With This Drug 

  • Avoid taking antidiabetics (insulin), stomach acid reducers (cimetidine), bronchodilators (theophylline), anticoagulants (warfarin), medicines or dietary supplements containing iron or zinc, antacids (aluminium hydroxide), corticosteroids (prednisone), and anti-inflammatory medications (ibuprofen) with Ofloxacin + Ornidazole. These medications may alter the safety and effectiveness of Ofloxacin + Ornidazole.

Overdose And Missed Dose

  • If by accident, you take an overdosage of Ofloxacin + Ornidazole, consult your doctor in case you experience any severe side effects or worsening of any of the symptoms. Strict adherence to the prescribed dose is essential.
  • If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This medicine can cause dizziness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • This combination is not recommended during pregnancy and breastfeeding.

Caution In Other Conditions

  • Caution is advised in older adults and patients with heart conditions, severe coagulation disorders and kidney and liver impairment.

Special Dietary And Lifestyle Recommendation

  • Take clear fluids like water, oral rehydration solutions, and diluted fruit juices. You can make an oral rehydration solution by mixing salt, sugar, and water to replenish electrolytes.
  • Dairy products and fatty foods can worsen diarrhoea. Avoid giving these until the symptoms improve.
  • Take foods with natural probiotics, like yoghurt, to help restore the balance of beneficial gut bacteria.
  • Give the smaller, more frequent meals to avoid stomach discomfort.
  • Emphasise the importance of keeping any cuts or wounds clean and properly covered to prevent skin infection from aggravating.

Frequently asked questions

This suspension can be used to treat diarrhoea associated with mixed infections, providing a comprehensive approach to address both bacterial and protozoal causes.

This suspension should be taken with or immediately after a meal as per your doctor’s advice, as it will help minimise the risk of stomach upset and enhance medication absorption. Consistency in the timing of administration is essential for optimal effectiveness.

The duration of treatment with this combination varies based on the specific infection and severity, and it should be given for the full prescribed course as directed by your doctor even if symptoms improve before completion. Follow the recommended treatment duration for optimal effectiveness.

Patients with a history of severe neurological disorders, kidney and liver impairment should not be given this combination without a doctor’s prescription.

This combination may rarely cause severe liver damage.

Terms & Conditions


Available medicines for Ofloxacin + Ornidazole
Zenflox Oz Tablet 10
Zenflox Oz Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
₹103.92
MRP ₹129.90
20.00% OFF
Ornof Tablet 10
Ornof Tablet 10
Aristo Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹114.28
MRP ₹142.85
20.00% OFF
O2 Tablet 10
O2 Tablet 10
Medley Pharmaceuticals
Pack of 10 Units
₹151.20
MRP ₹189.00
20.00% OFF
Nor Metrogyl Plus Tablet 10
Nor Metrogyl Plus Tablet 10
Lekar Pharma Ltd
Pack of 10 Units
₹77.37
MRP ₹96.71
20.00% OFF
Oflokem Oz 200/500 MG Tablet 6
Oflokem Oz 200/500 MG Tablet 6
Alkem Laboratories Ltd.
Pack of 6 Units
₹23.86
MRP ₹29.82
20.00% OFF
Oflotas Oz Tablet 10
Oflotas Oz Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹70.36
MRP ₹141.00
50.10% OFF
Office Oz Tablet 10
Office Oz Tablet 10
Hetero Healthcare Ltd
Pack of 10 Units
₹46.00
MRP ₹57.50
20.00% OFF
Oflox Oz Tablet 10
Oflox Oz Tablet 10
Cipla Ltd.
Pack of 10 Units
₹145.56
MRP ₹181.95
20.00% OFF

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