Home/Drugs By Ailments / Ofloxacin + Ornidazole

Ofloxacin + Ornidazole

Antibiotic

Uses of Ofloxacin + Ornidazole

Ofloxacin + Ornidazole is a combination antibiotic used to treat infections caused by both bacteria and certain protozoa, particularly in the digestive tract and reproductive system.

This combination is commonly used for:

  • Diarrhoea and dysentery: Treats acute diarrhoea caused by bacterial and parasitic infections, including amoebic dysentery.
  • Gastrointestinal infections: Addresses stomach and intestinal infections caused by mixed bacterial and anaerobic organisms.
  • Pelvic inflammatory disease (PID): Helps treat infections of the uterus, fallopian tubes, and ovaries caused by bacteria.
  • Bacterial vaginosis: Treats abnormal vaginal bacterial overgrowth leading to discharge and discomfort.
  • Dental and oral infections: Treats bacterial infections in the gums and surrounding tissue.
  • Mixed bacterial and protozoal infections: Treats infections where both bacterial and protozoal organisms are suspected or confirmed.

Side effects of Ofloxacin + Ornidazole

The  side effects of Ofloxacin + Ornidazole are:

  • Nausea and vomiting
  • Abdominal pain
  • Headache
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Itching
  • Vaginal inflammation
  • Diarrhoea

How Ofloxacin + Ornidazole works

Ofloxacin + Ornidazole works through two separate mechanisms to tackle bacterial and protozoal infections together.
 

  • Ofloxacin is a fluoroquinolone antibiotic: It works by blocking an enzyme called DNA gyrase, which bacteria need to copy and repair their DNA. Without this enzyme, bacteria cannot multiply or survive, which clears the infection.
     
  • Ornidazole is a nitroimidazole antiprotozoal and antibacterial agent: Inside bacteria and protozoa, it is converted into active compounds that interfere directly with DNA. This damages the genetic material of the microorganism, stopping it from reproducing and eventually killing it. Ornidazole is particularly effective against anaerobic bacteria and protozoa such as Giardia and Entamoeba.
     

Together, Ofloxacin and Ornidazole cover a broader range of infections than either medicine alone. Ofloxacin targets aerobic bacteria, while Ornidazole targets anaerobic bacteria and certain protozoa, making this a useful treatment for mixed infections.

Certified content

Written By

docImg
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years

MBBS

Reviewed By

Dr. Mandeep Chadha
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Expert Advice

Dosage Forms Available for Ofloxacin + Ornidazole

  • Ofloxacin + Ornidazole can be taken orally (tablet).

Age And Dosage Restrictions for Ofloxacin + Ornidazole

  • This combination is intended for adults and children. 

Contraindications of Ofloxacin + Ornidazole

  • This combination is contraindicated in patients with a history of hypersensitivity to ofloxacin or ornidazole. It is also contraindicated in patients having central nervous system disease, peripheral nervous system disease, liver and kidney impairment. 

Medications To Avoid With Ofloxacin + Ornidazole 

  • Avoid taking antidiabetics (insulin), stomach acid reducers (cimetidine), bronchodilators (theophylline), anticoagulants (warfarin), medicines or dietary supplements containing iron or zinc, antacids (aluminium hydroxide), corticosteroids (prednisone), and anti-inflammatory medications (ibuprofen) with Ofloxacin + Ornidazole. These medications may alter the safety and effectiveness of Ofloxacin + Ornidazole.

Overdose And Missed Dose

  • Taking more than the prescribed dose may cause nausea, vomiting, dizziness, headache, or seizures. If you accidentally take an overdose and notice any worsening of symptoms, contact your doctor or visit the nearest hospital without delay. Strict adherence to the prescribed dose is essential.
  • If you miss a dose of Ofloxacin + Ornidazole, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time. Completing the full prescribed course is important to prevent the infection from returning or becoming resistant to antibiotics.

Management Of Side Effects

  • Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This medicine can cause dizziness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • This combination is not recommended during pregnancy and breastfeeding.

Caution In Other Conditions

  • Caution is advised in older adults and patients with heart conditions, severe coagulation disorders and kidney and liver impairment.

Special Dietary And Lifestyle Recommendation

  • Take clear fluids like water, oral rehydration solutions, and diluted fruit juices. You can make an oral rehydration solution by mixing salt, sugar, and water to replenish electrolytes.
  • Dairy products and fatty foods can worsen diarrhoea. Avoid giving these until the symptoms improve.
  • Take foods with natural probiotics, like yoghurt, to help restore the balance of beneficial gut bacteria.
  • Give the smaller, more frequent meals to avoid stomach discomfort.
  • Emphasise the importance of keeping any cuts or wounds clean and properly covered to prevent skin infection from aggravating.

Frequently asked questions

Ofloxacin + Ornidazole is used to treat mixed infections caused by bacteria and parasites. It is commonly prescribed for conditions such as severe diarrhoea, dysentery, stomach and intestinal infections, and certain gynaecological infections. This combination works by stopping the growth of harmful germs, helping control the infection and supporting faster recovery.

Yes, Ofloxacin + Ornidazole treats loose motions.

It is advisable to avoid alcohol while on Ofloxacin + Ornidazole.

Store Ofloxacin + Ornidazole at room temperature below 30°C away from moisture. For disposal, follow the instructions on the package insert or contact your nearest pharmacist.

This suspension can be used to treat diarrhoea associated with mixed infections, providing a comprehensive approach to address both bacterial and protozoal causes.

This suspension should be taken with or immediately after a meal as per your doctor’s advice, as it will help minimise the risk of stomach upset and enhance medication absorption. Consistency in the timing of administration is essential for optimal effectiveness.

The duration of treatment with this combination varies based on the specific infection and severity, and it should be given for the full prescribed course as directed by your doctor even if symptoms improve before completion. Follow the recommended treatment duration for optimal effectiveness.

Patients with a history of severe neurological disorders, kidney and liver impairment should not be given this combination without a doctor’s prescription.

This combination may rarely cause severe liver damage.

Yes, Ofloxacin + Ornidazole treats loose motions.It Also used to treat infectious diarrhea. It helps control bowel movements, fight the infection, and prevent symptoms from coming back.

Terms & Conditions


List of medicines for Ofloxacin + Ornidazole

Nor Metrogyl Plus Tablet 10
Nor Metrogyl Plus Tablet 10
Lekar Pharma Ltd
Pack of 10 Units
₹86.58
MRP ₹109.59
21% OFF
O2 Tablet 10
O2 Tablet 10
Medley Pharmaceuticals
Pack of 10 Units
₹171.16
MRP ₹213.95
20% OFF
Ornof Tablet 10
Ornof Tablet 10
Aristo Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹123.74
MRP ₹154.68
20% OFF
Office Oz Tablet 10
Office Oz Tablet 10
Hetero Healthcare Ltd
Pack of 10 Units
₹50.74
MRP ₹59
14% OFF
Zenflox Oz Tablet 10
Zenflox Oz Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
₹129.66
MRP ₹162.07
20% OFF
Oflotas Oz Tablet 10
Oflotas Oz Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹72.66
MRP ₹145.31
50% OFF
Oflox Oz Tablet 10
Oflox Oz Tablet 10
Cipla Ltd.
Pack of 10 Units
₹165.11
MRP ₹206.39
20% OFF
Olox Oz Tablet 10
Olox Oz Tablet 10
Cipla Ltd.
Pack of 10 Units
₹70.27
MRP ₹175.68
60% OFF

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Registered Office Address

Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346

Grievance Officer

Name: Kishor Kumar

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Playstore
Apple App  Store

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v4.28.1

copyright

2026 - Truemeds | All rights reserved. Our content is for informational purposes only. See additional information.

Trust Certified

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner