Ofloxacin + Ornidazole is a combination medicine used for selected gastrointestinal infections caused by susceptible bacteria, anaerobic organisms, or protozoa.
This combination is commonly used for:
• Infectious diarrhoea: May be prescribed for acute diarrhoea caused by susceptible bacteria or protozoa when antimicrobial treatment is needed.
• Dysentery: Treats selected cases of bacterial or amoebic dysentery, as directed by a doctor.
• Mixed gastrointestinal infections: Targets susceptible aerobic bacteria, anaerobic bacteria, and protozoa when more than one type of organism is involved.
• Amoebiasis with suspected bacterial co-infection: May be used when both amoebic and bacterial causes require treatment.
• Giardiasis with suspected bacterial co-infection: May be used in selected mixed infections under medical supervision.
• Other confirmed mixed infections: Used only when a clinician determines that both components are appropriate for the likely or confirmed organisms.
The side effects of Ofloxacin + Ornidazole are:
Ofloxacin + Ornidazole works through two separate actions against susceptible bacteria, anaerobic organisms, and protozoa in selected infections.
Ofloxacin is a fluoroquinolone antibiotic. It blocks bacterial DNA gyrase and topoisomerase IV, enzymes that susceptible bacteria need to copy and repair their DNA. This stops bacterial multiplication.
Ornidazole is activated inside anaerobic bacteria and protozoa and forms compounds that damage their DNA. This prevents the organisms from reproducing and leads to their destruction.
Together, these medicines provide antibacterial and antiprotozoal activity when a mixed infection has been diagnosed or is strongly suspected."
Together, Ofloxacin and Ornidazole cover a broader range of infections than either medicine alone. Ofloxacin targets aerobic bacteria, while Ornidazole targets anaerobic bacteria and certain protozoa, making this a useful treatment for mixed infections.

MBBS

MBBS, DNB (OBGY)
Frequently asked questions
Ofloxacin + Ornidazole is used to treat mixed infections caused by bacteria and parasites. It is commonly prescribed for conditions such as severe diarrhoea, dysentery, stomach and intestinal infections, and certain gynaecological infections. This combination works by stopping the growth of harmful germs, helping control the infection and supporting faster recovery.
Yes, Ofloxacin + Ornidazole treats loose motions.
It is advisable to avoid alcohol while on Ofloxacin + Ornidazole.
Store Ofloxacin + Ornidazole at room temperature below 30°C away from moisture. For disposal, follow the instructions on the package insert or contact your nearest pharmacist.
This suspension can be used to treat diarrhoea associated with mixed infections, providing a comprehensive approach to address both bacterial and protozoal causes.
This suspension should be taken with or immediately after a meal as per your doctor’s advice, as it will help minimise the risk of stomach upset and enhance medication absorption. Consistency in the timing of administration is essential for optimal effectiveness.
The duration of treatment with this combination varies based on the specific infection and severity, and it should be given for the full prescribed course as directed by your doctor even if symptoms improve before completion. Follow the recommended treatment duration for optimal effectiveness.
Patients with a history of severe neurological disorders, kidney and liver impairment should not be given this combination without a doctor’s prescription.
This combination may rarely cause severe liver damage.
Yes, Ofloxacin + Ornidazole treats loose motions.It Also used to treat infectious diarrhea. It helps control bowel movements, fight the infection, and prevent symptoms from coming back.
Ofloxacin + Ornidazole in other salts








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