Levofloxacin + Ornidazole

Dosage Forms Available

• This combination is available for oral use in the form of tablets, suspension, and infusion/injections.

Age And Dose Restrictions

• This combination is intended for use in adults and children only as advised by the doctor.

Contraindications

• This combination is contraindicated in patients with known hypersensitivity to Levofloxacin, Ornidazole, fluoroquinolone antibiotics, nitroimidazole medicines, or any of the excipients. It is also contraindicated in patients with a history of myasthenia gravis, epilepsy, tendon disorders related to fluoroquinolone use, severe liver disease, and certain heart rhythm disorders associated with QT prolongation.

Other Medications To Avoid With This Medicine

• This combination may interact with antacids containing aluminium or magnesium, iron supplements, corticosteroids (prednisolone), anticoagulants (warfarin), QT-prolonging medicines (such as amiodarone and erythromycin), antidiabetic medicines, and non-steroidal anti-inflammatory drugs which may increase the risk of nervous system-related side effects such as seizures. These medicines may increase the risk of tendon injury, irregular heartbeat, nervous system-related side effects, bleeding, or reduced effectiveness of this combination.

Overdose And Missed Dose

• Overdose of this combination may cause confusion, seizures, severe dizziness, vomiting, irregular heartbeat, and nervous system-related side effects. Immediate medical attention may be required if these symptoms occur.
• If you forget to take this combination, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose.

Management Of Side Effects

• Most side effects are temporary, mild, and usually resolve after discontinuation of the medicine. However, if you experience severe diarrhoea, tendon pain, allergic reactions, or worsening of any symptoms, consult your doctor. Taking this combination after meals and maintaining adequate hydration may help reduce stomach discomfort.

Use In Driving And Operating Machinery

• This combination may cause dizziness, drowsiness, or reduced alertness in some individuals. Avoid driving or operating heavy machinery if you experience these symptoms.

Use In Pregnancy And Lactation

• This combination is generally not recommended during pregnancy and breastfeeding unless clearly advised by your doctor.

Caution In Other Conditions

• Caution is advised in older adults and patients with liver impairment, kidney problems, diabetes, epilepsy, tendon disorders, heart rhythm disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency or nervous system-related conditions.

Special Dietary And Lifestyle Recommendation

• Avoid alcohol consumption during treatment and for a few days after completion of therapy, as it may increase the risk of side effects.
• Drink adequate fluids throughout the day to help maintain hydration and support recovery.
• Avoid excessive physical activity if you experience tendon pain or muscle discomfort during treatment.
• Maintain proper hand hygiene and consume safe, hygienically prepared food and water to help prevent gastrointestinal infections.
• Complete the full prescribed course of treatment even if symptoms improve earlier.