Famotidine

Dosage forms available

• Famotidine is available in various oral dosage forms, including tablets, chewable tablets, oral suspensions and injectable form.

Age and dose restrictions

• Famotidine is generally safe for adults and children over 1 year old when used under medical supervision. 

Contraindications

• Famotidine should not be used by individuals with a known allergy to famotidine or other H2 receptor blockers. Caution is also advised in patients with a history of acute porphyria.

Other medications to avoid

• Avoid using famotidine with antifungals (e.g., ketoconazole), HIV protease inhibitors (e.g., atazanavir), certain antibiotics (e.g., cefuroxime), and cancer medications (e.g.,erlotinib) as famotidine may reduce their absorption or effectiveness. NSAIDs should also be used cautiously, as they may worsen stomach issues even when combined with famotidine.

Overdose and missed dose

• Overdose of famotidine is rare but may lead to symptoms such as confusion, dizziness, and irregular heartbeat. Seek medical help immediately in case of overdose. 
• If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed one and continue with your regular dosing schedule.

Management of side effects

• To manage minor side effects such as constipation, ensure adequate fluid intake and consume fiber-rich foods. In case of persistent headache or dizziness, rest and avoid strenuous activities. 
• If any side effects become severe or do not resolve, consult your healthcare provider for further evaluation and possible adjustments to your treatment plan.

Use in driving and operating machinery

• Famotidine may cause dizziness or drowsiness in some individuals. Avoid driving, operating heavy machinery, or engaging in tasks requiring mental alertness until you know how famotidine affects you.

Use in pregnancy and lactation

• Famotidine should only be used during pregnancy if clearly needed and prescribed by a healthcare provider. It is excreted in breast milk, so caution is advised when used by breastfeeding mothers.

Caution in other conditions

• Famotidine should be used with caution in patients with kidney or liver impairment. Patients with a history of gastric malignancy should be monitored, as famotidine may mask symptoms. It should also be used cautiously in older adults due to the increased risk of confusion and side effects.

Special dietary and lifestyle recommendations

• Limit intake of spicy, fried, and acidic foods to prevent irritation of the stomach lining.
• Avoid alcohol and smoking, as they may worsen gastrointestinal symptoms. 
• Maintain a healthy weight and eat smaller, more frequent meals to reduce acid reflux episodes. 
• Elevating the head while sleeping may also reduce nighttime reflux symptoms.