Chlorpheniramine + Dextromethorphan Hydrobromide + Phenylephrine is a combination medicine used to relieve symptoms of the common cold, flu, allergies, and hay fever.
This combination is commonly used for:
• Common cold and flu: Relieves sneezing, a runny nose, and nasal congestion.
• Allergies and hay fever: Eases itching, watery eyes, and nasal symptoms caused by allergens.
• Dry cough: Reduces the urge to cough associated with colds and upper respiratory infections.
• Nasal congestion: Relieves a blocked or stuffy nose.
Drowsiness
Dry mouth or throat
Mild headache
Nausea or vomiting
Constipation
Chlorpheniramine + Dextromethorphan Hydrobromide + Phenylephrine combines three medicines to relieve multiple cold and allergy symptoms together.
Chlorpheniramine is an antihistamine. It blocks histamine, a chemical that causes allergic symptoms such as a runny nose, sneezing, and itching.
Dextromethorphan Hydrobromide is a cough suppressant. It acts on the cough centre in the brain to reduce the urge to cough.
Phenylephrine is a decongestant. It narrows blood vessels in the nasal passages, reducing swelling and making it easier to breathe.
Together, these ingredients relieve a runny nose, sneezing, itchy eyes, and cough associated with colds, flu, and allergies.

Doctor of Medicine

BAMS, FMC, MD Resident
Chlorpheniramine + Dextromethorphan Hydrobromide + Phenylephrine is available for use via oral route in various forms including oral solution (liquid), capsules, tablets, and syrup.
This combination medicine is intended for adults and children above the age of 12 years.
This combination is contraindicated in patients with known allergies to any of its active ingredients.
It is also contraindicated in patients with high blood pressure, heart disease, thyroid disorders, diabetes, enlarged prostate, peptic ulcer disease, and certain breathing problems such as asthma, emphysema, and chronic bronchitis.
This combination may interact with MAO inhibitors (such as phenelzine and tranylcypromine), other antihistamines (like cetirizine and loratadine), decongestants (like pseudoephedrine), narcotic analgesics (such as morphine), sedatives or tranquillizers (like diazepam), antidepressants (like fluoxetine) and blood pressure medications (like enalapril and lisinopril).
Taking more than the prescribed dose may cause severe drowsiness, slow or shallow breathing, seizures, confusion, or hallucinations. Inform your doctor immediately if you notice any of these symptoms.
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help alleviate dry mouth, throat, and constipation.
Avoiding caffeine and spicy foods may help manage nausea or upset stomach.
Resting in a quiet, dark room may help manage headaches.
This combination medicine may cause drowsiness or dizziness. As such, avoid driving, operating machinery, or performing other tasks requiring alertness until you know how this medicine affects you.
It is advised to consult your doctor before using this medicine if you are pregnant or breastfeeding.
Patients with liver or kidney disease should exercise caution when taking this medicine.
Regular intake of balanced, nutritious meals can help strengthen immunity and speed up recovery from colds and flu.
Adequate rest and hydration can help manage symptoms and support recovery.
Avoiding allergens and maintaining a clean environment can help prevent allergic symptoms.
Frequently asked questions
No, Chlorpheniramine + Dextromethorphan Hydrobromide + Phenylephrine is not habit-forming or addictive. However, it is always advised to take this medicine as per the doctor's instructions.
You should continue taking the medicine as recommended by your doctor even if your symptoms improve. Stopping it abruptly can lead to a return of the symptoms.
The exact time might vary depending on individual responses, but typically, users can start noticing an improvement in symptoms within an hour or two of taking the medication.
Prolonged use of this medication is not generally recommended, as it is designed to manage symptoms of cold, flu, and allergies temporarily. If symptoms persist or worsen over an extended period, consult your doctor for advice.
While in many cases, this combination is available over the counter, regulations may vary. Always check with your local pharmacy or consult your doctor.
Yes, the antihistamine component of this combination, Chlorpheniramine, helps manage symptoms associated with allergies such as runny nose, sneezing, and itchy eyes.
Yes, one of the common side effects of Chlorpheniramine, an active ingredient in this combination, is drowsiness or sedation.
Chlorpheniramine + Dextromethorphan Hydrobromide + Phenylephrine in other salts

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