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Vildagliptin

Antidiabetic

Uses of Vildagliptin

  • Vildagliptin is used in the management of type 2 diabetes mellitus. 
  • It helps control blood sugar levels in adults when diet and exercise alone are not sufficient. 

Side effects of Vildagliptin

  • Headache
  • Dizziness
  • Fatigue
  • Nausea
  • Hypoglycemia (low blood sugar), especially when used with other antidiabetic medicines
  • Upper respiratory tract infections
  • Joint pain

How Vildagliptin works

  • Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. 
  • It works by increasing the levels of incretin hormones in the body, which stimulate insulin release from the pancreas and reduce the production of glucagon. 
  • This helps lower blood glucose levels, especially after meals, and improves overall glycemic control in type 2 diabetes patients.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 4 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Vildagliptin is available in oral tablet form.

Age and Dose Restrictions

  • Vildagliptin is not recommended for use in children and adolescents below 18 years of age.

Contraindications

  • Vildagliptin should not be used by individuals with a known allergy to the medicine or any of its components. It is also contraindicated in patients with severe kidney or liver impairment, heart failure, or diabetic ketoacidosis. Patients with a history of pancreatitis should use it with caution.

Other Medications to Avoid

  • Avoid taking Vildagliptin with strong CYP3A4 inhibitors (such as ketoconazole and ritonavir), corticosteroids, diuretics (such as furosemide), and certain antiepileptics (such as phenytoin). These medications may interfere with its effectiveness or increase the risk of side effects. Always inform your doctor about all the medications you are taking before starting Vildagliptin.

Overdose and Missed Dose

  • Overdose of Vildagliptin may cause severe hypoglycemia or liver enzyme abnormalities. In case of overdose, seek immediate medical attention. 
  • If you miss a dose, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

  • To manage mild side effects like dizziness or headache, stay hydrated and take adequate rest. If hypoglycemia occurs, consume a source of quick sugar such as fruit juice, candy, or glucose tablets. Persistent or severe side effects such as joint pain, liver enzyme changes, or allergic reactions should be reported to a doctor immediately.

Use in Driving and Operating Machinery

  • Vildagliptin may cause dizziness, which can impair concentration and alertness. If you experience dizziness, avoid driving, operating heavy machinery, or engaging in activities that require full attention until you know how the medication affects you.

Use in Pregnancy and Lactation

  • Vildagliptin is not recommended for use during pregnancy and breastfeeding due to a lack of sufficient safety data. If you are pregnant, planning to conceive, or breastfeeding, consult your doctor before using this medication.

Caution in Other Conditions

  • Vildagliptin should be used cautiously in patients with kidney or liver disease, heart conditions, or a history of pancreatitis. Regular monitoring of blood sugar levels, liver enzymes, and kidney function is advised while taking this medication.

Special Dietary and Lifestyle Recommendations

  • Follow a healthy, balanced diet with low-glycemic index foods such as whole grains, vegetables, and lean proteins to improve blood sugar control.
  • Engage in regular physical activity to enhance insulin sensitivity and maintain a healthy weight.
  • Stay hydrated and avoid excessive consumption of sugary beverages.
  • Monitor your blood sugar levels regularly and keep track of any fluctuations to adjust your treatment plan accordingly.

Frequently asked questions

Vildagliptin starts working within a few hours after ingestion, but significant blood sugar improvements may take a few weeks of regular use.

Yes, Vildagliptin can be taken with or without food. However, taking it with meals may help reduce the risk of gastrointestinal side effects.

This medication is generally weight-neutral, meaning it does not cause significant weight gain or loss. However, individual responses may vary.

Yes, this medication can be used long-term for managing type 2 diabetes, but regular monitoring of kidney and liver function is recommended.

Vildagliptin should be used with caution in patients with kidney disease. Dose adjustments may be required based on kidney function tests.

No, this medication is a prescription medication and should only be used under the supervision of a healthcare provider.

Yes, Vildagliptin can be used alone or in combination with other antidiabetic medications, depending on individual blood sugar levels and medical needs.

Terms & Conditions


List of Medicines for Vildagliptin

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