S-Amlodipine + S-Metoprolol
Uses of S-Amlodipine + S-Metoprolol
S-Amlodipine + S-Metoprolol is used to manage high blood pressure (hypertension), combining a calcium channel blocker with a beta blocker.
This combination is commonly used for:
• Hypertension: Lowers persistently high blood pressure through two complementary mechanisms.
• Angina pectoris: Helps prevent chest pain caused by reduced blood flow to the heart.
• Reducing angina frequency: Lowers the number of angina episodes in people with coronary artery disease.
• Improving exercise capacity: Supports greater physical activity tolerance in people with angina or hypertension.
Side effects of S-Amlodipine + S-Metoprolol
Dizziness
Headache
Fatigue
Nausea
Swelling in the limbs (Oedema)
How S-Amlodipine + S-Metoprolol works
S-Amlodipine + S-Metoprolol works through two separate mechanisms to lower blood pressure and manage angina.
S-Amlodipine is a calcium channel blocker. It relaxes and widens blood vessels, allowing blood to flow more smoothly, which lowers blood pressure and reduces the heart's workload.
S-Metoprolol is a beta blocker. It acts on the heart to slow the heart rate and reduce the force of its contractions, lowering the heart's oxygen demand, reducing blood pressure, and helping maintain a regular heartbeat.
Together, both medicines provide more effective blood pressure control and reduce strain on the heart than either medicine alone.
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Written By
MSc (Applied Genetics)
Reviewed By
BAMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
S-Amlodipine + S-Metoprolol is available in the form of oral tablets.
Age and Dose Restrictions
This medicine is intended for use in adults.
Contraindications
S-Amlodipine + S-Metoprolol is contraindicated in patients with known allergies to either S-Amlodipine or S-Metoprolol.
It is also contraindicated in patients with cardiogenic shock, severe bradycardia, second or third-degree heart block, acute heart failure, or severe liver disease.
Other Medications to Avoid
This combination can interact with antifungal - CYP3A4 inhibitors (e.g., itraconazole, ketoconazole), antibacterial agents - CYP3A4 inducers - (e.g., rifampicin), anti-convulsants (e.g., phenytoin), and CYP2D6 inhibitors - selective serotonin reuptake inhibitors (e.g, fluoxetine, paroxetine).
Overdose and Missed Dose
Taking more than the prescribed dose may cause severe side effects such as an irregular heartbeat, difficulty breathing, or fainting. If you suspect an overdose, consult your doctor immediately.
If you miss a dose of S-Amlodipine + S-Metoprolol, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help manage minor side effects such as dizziness and headache.
If you experience constipation, try to include more fibre-rich foods in your diet and drink plenty of fluids.
Use in Driving and Operating Machinery
This medication may cause dizziness. If you feel dizzy after taking this medication, avoid driving or operating heavy machinery until you feel well.
Use in Pregnancy and Lactation
The safety of S-Amlodipine + S-Metoprolol during pregnancy and breastfeeding has not been established. Thus, it should be used only if the potential benefits justify the risk to the fetus or child. Always consult your doctor before using this medicine during pregnancy or while breastfeeding.
Caution in Other Conditions
Caution is advised for patients with mild to moderate liver impairment or kidney disease. Regular monitoring of liver and kidney function is required while taking this medicine.
Special Dietary and Lifestyle Recommendations
Cut down on salt in your diet as it can raise your blood pressure.
Monitor your blood pressure regularly to ensure the medicine is working effectively.
Frequently asked questions
Can S-Amlodipine + S-Metoprolol cause weight gain?
No, weight gain is not one of the common side effects of S-Amlodipine + S-Metoprolol. However, if you notice any unusual changes in your weight while taking this medicine, please consult your doctor.
Can I take S-Amlodipine + S-Metoprolol without having hypertension?
No, S-Amlodipine + S-Metoprolol is a medicine that is used to manage hypertension. It should not be taken without a medical diagnosis and the advice of a doctor.
Does S-Amlodipine + S-Metoprolol have any effect on cholesterol levels?
S-Amlodipine + S-Metoprolol is primarily used to manage high blood pressure and does not have a direct effect on cholesterol levels. If you have high cholesterol levels, you should consult your doctor for appropriate management.
Will the use of S-Amlodipine + S-Metoprolol affect my mood?
In some cases, patients using S-Amlodipine + S-Metoprolol may experience mood changes or depression as a side effect. If you experience mood changes or feel depressed, please consult your doctor.
Should I avoid any specific food items while taking S-Amlodipine + S-Metoprolol?
There are no specific food items that you need to avoid during your treatment with S-Amlodipine + S-Metoprolol. However, maintaining a balanced diet can help control your blood pressure and overall health.
How long does the effect of S-Amlodipine + S-Metoprolol last in the body?
The duration of effect can vary from person to person and depends on multiple factors such as the dosage of the medicine, the individual's metabolism, and other medical conditions. Please consult your doctor for specific information.
Can S-Amlodipine + S-Metoprolol cause allergies?
It is possible to have an allergic reaction to any medication. If you notice signs of an allergic reaction such as skin rashes, itching, swelling, or difficulty breathing after taking S-Amlodipine + S-Metoprolol, seek immediate medical attention.
List of medicines for S-Amlodipine + S-Metoprolol
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