Home/Drugs By Ailments / Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine

Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine

Uses of Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine

  • Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine is primarily used for the temporary relief of symptoms associated with the common cold, flu, and other upper respiratory allergies. This combination belongs to the group of upper respiratory combinations.

  • Additionally, it helps manage nasal and sinus congestion, cough due to minor throat and bronchial irritation, sneezing, runny nose, and itchy, watery eyes due to hay fever, or other upper respiratory allergies.

Side effects of Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine

  • Drowsiness or dizziness

  • Headache

  • Dry mouth, nose, or throat

  • Nausea or vomiting

  • Constipation

How Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine works

  • Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine is an upper respiratory combination of an antihistamine, a cough suppressant, an expectorant, and a decongestant.

  • Chlorpheniramine is an antihistamine. Histamine is a substance that your body makes during an allergic reaction, and it can lead to symptoms like sneezing and watery eyes. Antihistamines like chlorpheniramine help to reduce these symptoms by blocking the effects of histamine.

  • Dextromethorphan is a cough suppressant. It works on the part of the brain that triggers coughing, helping to reduce the urge to cough.

  • Guaifenesin is an expectorant. It works by thinning and loosening the mucus in your airways, making it easier for you to cough up and clear out.

  • Phenylephrine is a decongestant. It shrinks swollen nasal tissues, helping to relieve congestion and make breathing easier.

Certified content

Written By

docImg
Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine is available in various formulations for oral administration, including tablets, capsules, liquid syrup, and extended-release tablets or capsules.

Age and Dose Restrictions

  • This combination is suitable for adults and children; however, it should not be given to children under four without consulting a doctor.

Contraindications

  • This combination is contraindicated in patients who have severe hypertension or coronary artery disease.

  • It is also contraindicated in patients who have taken monoamine oxidase inhibitors (MAOIs) within the past 14 days.

Other Medications to Avoid

  • This combination may interact with MAOIs (such as phenelzine and tranylcypromine), antidepressants (like sertraline, amitriptyline, and fluoxetine), beta-blockers (including propranolol and atenolol), diuretics (such as furosemide and hydrochlorothiazide), certain cardiac glycosides (like digoxin), and sedatives or tranquillisers (like diazepam and alprazolam).

Overdose and Missed Dose

  • An overdose of Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine can lead to symptoms such as severe dizziness, increased heart rate, and confusion. If such symptoms are observed, it is crucial to seek medical attention immediately.

  • If you miss a dose of this combination, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing dry mouth, sip water regularly or use sugar-free gum to keep the mouth moist.

  • In case of mild dizziness, try lying down until the sensation passes.

Use in Driving and Operating Machinery

  • This combination can cause drowsiness or dizziness. You should avoid driving or operating heavy machinery if you feel affected in this way after taking the medicine.

Use in Pregnancy and Lactation

  • Consult your doctor before using Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine if you are pregnant or breastfeeding. It is important to assess the benefits against any potential risks to the mother and child with your doctor's guidance.

Caution in Other Conditions

  • Individuals with conditions such as thyroid disorders, diabetes, glaucoma, prostate enlargement, or those with known difficulties in urination should exercise caution when using this combination.

Special Dietary and Lifestyle Recommendations

  • Maintain adequate hydration, especially if experiencing dry mouth due to this medication.

  • Engage in light to moderate exercise regularly that may help improve your respiratory health.

  • Avoid exposure to allergens that might trigger respiratory symptoms requiring the use of this medication.

Frequently asked questions

No, Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine is not a steroid. This combination is made of four different active ingredients that work together to manage symptoms associated with the common cold, flu, and other upper respiratory allergies.

One of the side effects of this combination could be drowsiness or dizziness. Therefore, it may affect your sleep patterns. It is recommended that you consult your doctor if you experience these symptoms persistently.

There are no substantial reports suggesting that this combination directly impacts fertility. However, if you have concerns regarding the same, it is advisable to consult your doctor.

There are no specific diet restrictions while taking this combination. However, it is always recommended to maintain a balanced and healthy diet during any medication course.

This combination is intended for temporary use and should be taken per your doctor's recommendation and guidance.

The time taken for the combination to show its effect can vary depending on the individual and the severity of the symptoms. It is best to follow your doctor's advice regarding the same.

The best time to take this combination can be determined by your doctor based on your health condition and how your body responds. It is important to follow the instructions given by your doctor.

Terms & Conditions


Chlorpheniramine + Dextromethorphan + Guaifenesin + Phenylephrine in other salts

AMBROXOL + GUAIFENESIN + LEVOSALBUTAMOLAMBROXOL + GUAIFENESIN + MENTHOL + TERBUTALINEAMBROXOL + GUAIFENESIN + TERBUTALINECHLORPHENIRAMINE MALEATEDEXTROMETHORPHAN HYDROBROMIDECETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDEBROMHEXINE + GUAIFENESIN + TERBUTALINECHLORPHENIRAMINE + PHENYLEPHRINECPM + DEXTROMETHORPHAN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINECPM + DEXTROMETHORPHAN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDEAMBROXOL + GUAIFENESIN + SALBUTAMOLPHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE + NAPHAZOLINECARBOXY METHYL CELLULOSE + NAPHAZOLINE + PHENYLEPHRINENAPHAZOLINE + PHENYLEPHRINECHLORPHENIRAMINE + CODEINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORBUTOL + PHENYLEPHRINE + TROPICAMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + GUAIFENESIN + LEVOSALBUTAMOL + MENTHOLCHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROMETHORPHANAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINEAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + CODEINEBROMHEXINE + GUAIFENESIN + MENTHOL + TERBUTALINEAMBROXOL + GUAIFENESIN + MENTHOL + SALBUTAMOLAMBROXOL + GUAIFENESIN + LORATADINEGUAIFENESIN + SALBUTAMOLGUAIFENESIN + TERBUTALINEBROMHEXINE + GUAIFENESIN + SALBUTAMOLAMBROXOL + CETIRIZINE + GUAIFENESINAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + SODIUM CITRATEAMBROXOL + AMMONIUM CHLORIDE + GUAIFENESIN + TERBUTALINEBROMHEXINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + PHENYLEPHRINE + SALBUTAMOLBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESINAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + MENTHOLBROMHEXINE + GUAIFENESIN + MENTHOL + SALBUTAMOLAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHAN HYDROBROMIDE + MENTHOLBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + MENTHOLCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHANAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + GUAIFENESINAMYLMETACRESOL + DEXTROMETHORPHAN HYDROBROMIDEAMBROXOL + GUAIFENESIN + LEVOSALBUTAMOL / LEVALBUTEROLCHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDEBROMHEXINE + CHLORPHENIRAMINE + DEXTROMETHORPHANCHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHANAMMONIUM CHLORIDE + CPM + DEXTROMETHORPHAN + GUAIFENESINAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE + LEVODROPROPIZINEACEBROPHYLLINE + GUAIFENESIN + TERBUTALINEDEXTROMETHORPHAN + TRIPROLIDINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + DEXTROMETHORPHANDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINECHLORPHENIRAMINE + DIETHYLCARBAMAZINEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + MENTHOL + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINEAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHAN + MENTHOLCETIRIZINE + DEXTROMETHORPHANCETIRIZINE + DEXTROMETHORPHAN + PSEUDOEPHEDRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINEBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESINDEXCHLORPHENIRAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLPROPANOLAMINEGUAIFENESINCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLPROPANOLAMINECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PHENYLEPHRINEAMBROXOL + DESLORATADINE + GUAIFENESIN + MENTHOLAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINBROMHEXINE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PHENYLEPHRINECHLORPHENIRAMINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHENBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DIETHYLCARBAMAZINEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PHENYLEPHRINE
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