Chlorpheniramine + Codeine is a combination medicine used to relieve dry cough and allergy symptoms caused by the common cold or allergic conditions.
This combination is commonly used for:
• Nonproductive cough: Suppresses a dry, irritating cough linked to colds or allergies.
• Allergic rhinitis and hay fever: Relieves sneezing, a runny nose, and itching of the nose or throat.
Drowsiness
Dizziness
Nausea
Vomiting
Dry mouth
Chlorpheniramine + Codeine works through two separate actions that relieve allergy symptoms and suppress cough.
Chlorpheniramine is an antihistamine. It blocks histamine, a chemical the body releases during an allergic reaction, which controls symptoms such as a runny nose, sneezing, and itchy eyes.
Codeine is an opioid. It acts on the cough centre in the brain to suppress the cough reflex, reducing the urge to cough.
Together, the combination relieves both dry cough and allergy symptoms associated with colds and hay fever.

BDS, MDS

BAMS, FMC, MD Resident
Chlorpheniramine + Codeine is available as tablets, solution, or extended-release suspension for oral administration.
This medicine is meant for use by adults and children above the age of 18 years.
This medicine is contraindicated in individuals with hypersensitivity to its components and patients with severe respiratory depression, a bowel obstruction known as paralytic ileus, and severe liver impairment.
Chlorpheniramine + Codeine may interact with other opioid pain medications (such as morphine and fentanyl), benzodiazepines (like lorazepam and diazepam), sleeping pills (such as zolpidem), muscle relaxants (like cyclobenzaprine), antidepressants (such as fluoxetine and amitriptyline), and medicines for Parkinson's disease (like bromocriptine and pramipexole), for overactive bladder (like oxybutynin and tolterodine), and for motion sickness or vertigo (like meclizine and scopolamine).
If you miss a dose of Chlorpheniramine + Codeine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.
To manage drowsiness, consider taking the medicine at bedtime.
For dry mouth, drink plenty of fluids or use ice chips.
This medicine may cause marked drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how this medicine affects you.
This combination is not recommended during pregnancy or breastfeeding. It may harm the foetus and can pass into breast milk, affecting the nursing baby. Consult your doctor before using this medication if pregnant or breastfeeding.
Caution is advised in using this medicine if you have breathing problems such as asthma, chronic obstructive pulmonary disease (COPD), or sleep apnoea, narrow-angle glaucoma, and kidney disease or urinary retention.
Drink plenty of fluids to help relieve congestion and keep hydrated.
Eat balanced meals to support overall health; include fruits, vegetables, lean proteins, and whole grains in your diet.
Maintain a regular sleep schedule to help manage fatigue associated with colds and allergies.
Avoid exposure to allergens like pollen, pet dander, and dust mites by keeping your living environment clean. Use air purifiers if necessary.
Limit or avoid smoking and exposure to second-hand smoke as it can exacerbate respiratory symptoms.
Manage stress through relaxation techniques such as yoga, meditation, or breathing exercises which can help alleviate symptoms triggered by stress.
Frequently asked questions
No. It is a combination medicine containing an antihistamine and an opioid pain reliever and cough suppressant.
Yes, one of its common side effects is drowsiness or sedation. It can, therefore, affect sleep patterns by making you sleepy or drowsy.
There is no scientific evidence to suggest that it affects fertility in humans. However, if you have concerns about this, please consult your doctor.
No specific diet restrictions have been noted for this medication. However, it is essential to maintain a balanced diet while on medication. If you have specific dietary concerns, please consult your doctor.
The safety of daily use of Chlorpheniramine + Codeine depends on the duration and dosage prescribed by your doctor. This medication should not be used for longer than recommended and should be taken only as directed.
The time taken can vary among individuals and depends on the severity of symptoms and individual response to the medication.
The best time to take it would be as directed by your doctor. It is generally taken when symptoms such as cough and allergic reactions are bothersome.
Company
About UsHealth ArticleHealth StoriesHealth LibraryDiseases & Health ConditionsAyurvedaUnderstanding Generic MedicinesAll MedicinesAll BrandsNeed HelpFAQSecuritySavings CalculatorAdvertise with UsSubscribe
Registered Office Address
Grievance Officer
Download Truemeds
Contact Us
Our customer representative team is available 7 days a week from 9 am - 9 pm.
v4.28.10
2026 - Truemeds | All rights reserved. Our content is for informational purposes only. See additional information.
Our Payment Partners

