Chloroquine

Dosage Forms Available

Chloroquine can be taken orally (tablet and oral suspension).

Age and Dose Restrictions

• This medication is suitable for adults and children of all ages.

Contraindications

• Chloroquine should not be used by individuals who have known hypersensitivity or allergy to any 4-aminoquinoline compounds. It is also contraindicated in patients with retinal or visual field changes due to potential ocular toxicity.

Other Medications to Avoid

• Chloroquine may interact with antacids (such as aluminium hydroxide and magnesium hydroxide), H2 blockers (like cimetidine), immunosuppressants (such as cyclosporine), antimalarial medications (such as mefloquine), and antibiotic medicines (like ampicillin and praziquantel).

Overdose and Missed Dose

• Overdosing on Chloroquine can lead to severe side effects such as vision problems, seizures, weak or shallow breathing, irregular heartbeats, or life-threatening heart problems. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of Chloroquine, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue your regular dosing schedule. Do not double your dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage gastrointestinal side effects like diarrhoea and stomach cramps.

• Taking Chloroquine with food may help reduce nausea and vomiting.

Use in Driving and Operating Machinery

• Chloroquine may cause dizziness or blurred vision in some individuals. Therefore, caution is advised when driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

• Chloroquine is generally considered safe for use in pregnancy for malaria prevention, as well as during breastfeeding. However, it is advised to consult your doctor before taking this medication.

Caution in Other Conditions

• Patients with pre-existing heart conditions or liver diseases should exercise caution when using Chloroquine as this medication can affect these organs.

Special Dietary and Lifestyle Recommendations

• Regular check-ups, especially ocular examinations, are recommended for long-term Chloroquine therapy patients.

• Practising mosquito avoidance measures such as wearing protective clothing, using insect repellent, and sleeping under mosquito nets can help prevent malaria in high-risk areas.

• Regularly washing hands and maintaining good hygiene can help prevent amebiasis.