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Sodium Citrate

Uses of Sodium Citrate

Sodium Citrate is used in different formulations as a urinary alkaliniser, systemic alkaliniser, antacid, or anticoagulant additive.

It is commonly used for:

  • Urinary alkalinisation: Makes urine less acidic in selected conditions, including some uric-acid or cystine stone disorders.
  • Metabolic acidosis: Provides an alkali source in selected patients, as prescribed by your doctor.
  • Antacid use: Selected oral formulations can temporarily neutralise stomach acid.
  • Blood collection and storage: Citrate binds calcium and prevents clotting outside the body.

The exact formulation and indication must be confirmed; sodium citrate should not be presented as a general treatment for gout or all kidney stones.

Side effects of Sodium Citrate

  • Nausea

  • Vomiting

  • Stomach upset

  • Diarrhoea

  • Swelling of the hands, ankles, or feet

How Sodium Citrate works

  • Sodium Citrate works primarily as a systemic and urinary alkaliniser.
  • Once ingested, Sodium Citrate is metabolised into bicarbonate ions in the body. Bicarbonate increases the pH of blood and urine, making them less acidic. Higher urine pH prevents uric acid and cysteine from precipitating into solid kidney stones and helps dissolve existing crystals.
  • In the stomach, Sodium Citrate reacts with excess gastric acid to neutralise acidity, offering prompt relief from burning and stomach irritation.

Certified content

Written By

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Dr Nikita LoboMedical Content Reviewer| 9 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi RoshaMedical Content Writer| 10 years

BAMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Sodium Citrate is available for use as an oral solution and in tablet and capsule forms.

  • The oral solution is consumed by dilution in water, while the tablets and capsules are taken orally with fluids as advised.

Age and Dose Restrictions

  • This medicine is suitable for adults and children. The specific age for administration can vary based on the condition being managed and the doctor's recommendation.

Contraindications

  • Sodium Citrate is contraindicated in patients with hypersensitivity to any of its components.

  • It is also not advisable for use in individuals with severe renal impairment or active urinary infections.

Other Medications to Avoid

  • This medicine may interact with aluminum-based antacids (such as aluminium hydroxide), salicylates (like aspirin), and medications affecting cardiac rhythm (such as quinidine).

Overdose and Missed Dose

  • In cases of overdose, symptoms such as severe nausea, vomiting, muscle twitching, or convulsions may occur. Immediate medical attention is recommended if overdose symptoms are observed.

  • If a dose of Sodium Citrate is missed, it should be taken as soon as remembered. However, if it is nearly time for the next scheduled dose, the missed dose should be skipped to avoid doubling up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea or stomach upset, try taking Sodium Citrate with or after food.

  • If experiencing diarrhoea, ensure adequate hydration by drinking plenty of fluids.

Use in Driving and Operating Machinery

  • Sodium Citrate does not generally affect the ability to drive or operate machinery. However, individual responses can vary, and it is important to avoid performing these activities if feeling unwell or dizzy after taking the medication.

Use in Pregnancy and Lactation

  • Consult your doctor before using Sodium Citrate during pregnancy or while breastfeeding. The safety of this medication for use in these conditions has not been fully established.

Caution in Other Conditions

  • Caution is advised when using Sodium Citrate in patients with heart conditions or those on a sodium-restricted diet due to its sodium content.

  • Individuals with a history of kidney stones should also consult a doctor before using Sodium Citrate, as adjustments in dosage might be required.

Special Dietary and Lifestyle Recommendations

  • Increase fluid intake to help prevent kidney stone formation; water is particularly beneficial.

  • Limit consumption of foods high in purines such as red meat and seafood to help manage conditions like gout Sodium Citrate is used for.

  • Consider adopting a balanced diet low in sodium and rich in fruits and vegetables to aid in controlling acid levels within the body.

  • Regular monitoring of blood pressure is advised for those on a sodium-restricted diet who are taking Sodium Citrate.

Frequently asked questions

Sodium Citrate is usually a prescription medicine and is not typically available over the counter. It should be used under the guidance of a doctor.

Sodium Citrate starts working within a few hours of administration. However, it may take several days to achieve the desired effect on urine pH and composition.

Yes, Sodium Citrate can be used long-term under medical supervision for the prevention of kidney stones and management of chronic metabolic acidosis.

If you miss a dose of Sodium Citrate, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule.

Sodium Citrate should be stored at room temperature, away from heat, light, and moisture. Never freeze the oral solution.

There is no evidence to suggest that Sodium Citrate directly affects mood or sleep patterns. If you experience unusual mood changes or disturbances in your sleep pattern while taking this medication, consult your doctor.

There are no specific foods or drinks that are known to interact with Sodium Citrate. However, patients on a sodium-restricted diet should consult their doctor before taking Sodium Citrate.

Terms & Conditions


List of medicines for Sodium Citrate

Cool 1.53 Gm Syrup 200 Ml
Cool 1.53 Gm Syrup 200 Ml
Diligence Pharma
Pack of 200 ML
₹81
MRP ₹101.25
20% OFF

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