Levosulpiride
AntacidUses of Levosulpiride
Levosulpiride is used to manage gastrointestinal conditions such as heartburn, bloating, nausea, and symptoms of irritable bowel syndrome (IBS). It is also prescribed for certain psychiatric conditions including depression.
Levosulpiride is commonly used for:
- Functional dyspepsia: Relieves symptoms such as upper abdominal discomfort, bloating, nausea, and the feeling of fullness after eating.
- Gastro-oesophageal reflux disease (GERD): Helps reduce symptoms of acid reflux including heartburn and regurgitation by improving the movement of food through the digestive tract.
- Irritable bowel syndrome (IBS): Eases bowel-related discomfort, bloating, and irregular bowel habits.
- Nausea and vomiting: Controls nausea and vomiting linked to digestive disorders or other causes.
- Depression: At higher doses, Levosulpiride may be prescribed for mild-to-moderate depression, particularly when digestive symptoms are also present.
- Schizophrenia: Used in the management of certain psychotic symptoms under specialist supervision.
Side effects of Levosulpiride
- Vertigo
- Weakness
- Dizziness
- Sleepiness
How Levosulpiride works
- Levosulpiride works through two key actions in the body: improving the movement of food through the digestive system and regulating chemical signals in the brain.
- In the digestive tract, Levosulpiride blocks dopamine D2 receptors found in the stomach and intestines. Dopamine normally slows down gut movement. By blocking these receptors, Levosulpiride speeds up the movement of food through the stomach and intestines, which relieves bloating, nausea, fullness, and heartburn. This type of action makes it a prokinetic agent.
- In the brain, Levosulpiride also blocks dopamine receptors and may also affect other neurotransmitter systems involved in mood regulation. This action helps regulate mood and manage symptoms of depression or psychotic disorders.
- Together, these mechanisms allow Levosulpiride to address both digestive discomfort and mood-related symptoms, depending on the dose and condition being treated.
Certified content
Written By
MBBS
Reviewed By
MBBS, DNB (OBGY)
Expert Advice
Dosage Forms Available
- Levosulpiride can be taken orally (tablet).
Age And Dose Restrictions
- This medication can be used in adults and children over 14 years of age.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to levosulpiride, in patients having pheochromocytoma, epilepsy, and maniac conditions.
Other Medications To Avoid With This Medicine
- Avoid taking antihypertensive medications (propranolol), antiarrhythmic agents (quinidine), diuretics (furosemide), and antidepressants (haloperidol) with this medication. These medications may alter the safety and effectiveness of levosulpiride.
Overdose And Missed Dose
- An overdose of Levosulpiride may cause symptoms such as involuntary muscle movements, restlessness, muscle stiffness, drowsiness, confusion, or a drop in blood pressure. These symptoms require prompt medical attention. If you suspect an overdose, contact your doctor or go to the nearest hospital immediately.
- If you miss a dose of Levosulpiride, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not double the dose to make up for the one you missed. Strict adherence to the prescribed dose is essential.
Use In Pregnancy And Lactation
- Caution is advised to take this medicine during pregnancy and breastfeeding women.
Caution In Other Conditions
- Caution should be taken while giving this medication in elderly patients in patients having liver and kidney diseases.
Special Dietary And Lifestyle Recommendation
- Avoid alcohol while taking this medication as it increases the sedative effects of this medicine.
- Opt for smaller, frequent meals to aid digestion.
- Say no to smoking and alcohol, which can worsen acidity and heartburn.
- Stay active with regular exercise to maintain a healthy weight.
- Avoid lying down right after eating to prevent reflux.
- Wear comfortable, loose-fitting clothes to ease digestion.
- Limit tea and soda intake to manage acidity.
- Take short breaks to walk or stretch every hour, avoiding prolonged sitting.
Frequently asked questions
1. Is Levosulpiride available over the counter, or do I need a prescription?
This medicine usually requires a prescription and is not available over the counter.
2. Is it safe to use Levosulpiride in elderly patients?
This medicine has to be used with caution in elderly patients as the side effects may worsen, especially in liver, kidney, and heart diseases.
3. Is Levosulpiride a habit forming medicine?
No, this medicine is not a habit forming medicine.
4. How much time does Levosulpiride take to work?
Within 1 to 2 hours, you must experience the benefit of Levosulpiride.
5. Should I stop taking Levosulpiride if I feel healthy?
No, please do not stop taking the medicine without first consulting your doctor. Sudden discontinuation of it does have the possibility of causing side effects, including acidity and heartburn.
6. Does taking Levosulpiride affect fertility?
No, it is unlikely to affect fertility in either men or women. However, there is currently insufficient evidence to justify any clear conclusion. Consult your doctor for the most accurate information.
7. Does taking Levosulpiride helpful in the treatment of gastric bleeding?
No, it reduces excessive stomach acid production, which causes acid reflux and heartburn. Consult your doctor immediately if you see any blood in your stool or mucous.
8. Does taking Levosulpiride cause sleepiness?
Yes, it may cause sleepiness. While using Levosulpiride, it is recommended that you should not drive or operate heavy machinery. It is suggested to relax until you feel better if you are experiencing sleep or dizziness.
9. What is Levosulpiride used for?
Levosulpiride is used to treat digestive disorders like nausea, vomiting, indigestion, and bloating. It helps improve digestion and is also used for irritable bowel syndrome (IBS), depression, and anxiety.
List of medicines for Levosulpiride
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