Ketorolac + Olopatadine is an eye medicine used to manage allergic conjunctivitis, an allergic reaction affecting the eyes.
This combination is commonly used for:
• Allergic conjunctivitis: Relieves eye redness, itching, and swelling caused by allergens.
• Eye itching and tearing: Eases itching and watering of the eyes linked to allergic reactions.
• Foreign body sensation in the eye: Reduces the gritty or irritated feeling that can accompany eye allergies.
Burning or stinging sensation in the eyes
Blurred vision
Headaches
Unpleasant taste in the mouth
Dry eyes
Ketorolac + Olopatadine works through two separate mechanisms to relieve allergic conjunctivitis.
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID). It blocks the production of natural substances in the body that cause inflammation, reducing redness and swelling in the eye.
Olopatadine is an antihistamine and mast cell stabiliser. It blocks histamine, a substance released during an allergic reaction, and prevents mast cells from releasing further inflammatory substances.
Together, Ketorolac and Olopatadine provide more complete relief from itching, redness, and swelling than either medicine used alone.

Doctor of Medicine

BAMS, FMC, MD Resident
Ketorolac + Olopatadine is available for use via topical route in the form of ophthalmic/eye drops.
This medicine is meant for adults, and children above 3 years of age.
Ketorolac + Olopatadine is contraindicated in patients with known hypersensitivity to either ketorolac or olopatadine.
It is also contraindicated in corneal complications.
Asthma and NSAID allergies.
Ketorolac is contraindicated in patients with known bleeding tendencies or conditions that increase bleeding risk since NSAIDs can prolong bleeding time by inhibiting platelet aggregation.
This combination may interact with oral NSAIDs (such as ibuprofen and naproxen), blood thinners (like warfarin and aspirin).
If you miss a dose of Ketorolac + Olopatadine, instil it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not instil a double dose to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If you experience dry eyes, consider using over-the-counter artificial tear drops to alleviate discomfort.
If headaches persist, try resting and keeping yourself hydrated.
Ketorolac + Olopatadine eye drops may cause temporary blurring of vision. Avoid driving or operating heavy machinery until your vision clears.
Consult your doctor before using this medicine during pregnancy and lactation.
Patients with bleeding disorders, active bleeding, recent eye surgery, severe dry eyes, or advanced kidney disease should exercise caution when using Ketorolac + Olopatadine.
Maintain good eye hygiene to prevent infections or further irritation.
Avoid rubbing your eyes as it can worsen the symptoms.
Frequently asked questions
No, Ketorolac + Olopatadine is not a steroid. It is a combination of two active ingredients: Ketorolac, which is an NSAID and Olopatadine, which is an antihistamine and mast cell stabiliser.
You should always inform your doctor about all the medications you are currently taking, including any other eye drops or ointments. The doctor will then decide whether it's safe for you to use them together with Ketorolac + Olopatadine.
While certain natural remedies may provide temporary relief from symptoms of allergic conjunctivitis, they are not a replacement for prescription medication like Ketorolac + Olopatadine. Always consult your doctor before starting or stopping any medication.
Most patients experience significant relief from symptoms of allergic conjunctivitis within 30 minutes to an hour after instilling Ketorolac + Olopatadine eye drops. However, individual responses can vary.
This combination is usually available only with a prescription and is not sold over the counter.
If the eye drops get contaminated, discard the bottle immediately to avoid potential eye infection.
Ketorolac and Olopatadine are generally not associated with significant effects on mood or behavior when used as prescribed.
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