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Ketorolac + Moxifloxacin

Uses of Ketorolac + Moxifloxacin

Ketorolac + Moxifloxacin is an eye medicine used to manage inflammation and prevent infection following eye surgery, and to treat bacterial eye infections.
This combination is commonly used for:
• Inflammation after cataract or refractive lens surgery: Reduces swelling and associated discomfort following these procedures.
• Prevention of infection after corneal refractive surgery: Lowers the risk of bacterial infection developing after surgery.
• Bacterial conjunctivitis: Treats infection caused by susceptible bacteria.
• Corneal infection following refractive surgery: Manages bacterial infection and associated inflammation affecting the cornea.

Side effects of Ketorolac + Moxifloxacin

  • Mild, transient burning, stinging and irritation upon instillation

  • Temporary blurred vision

  • Headache

  • Eye itching, redness, dryness and discomfort

  • Bitter taste

How Ketorolac + Moxifloxacin works

  • Ketorolac + Moxifloxacin works through two separate mechanisms to reduce eye inflammation and clear bacterial infection.
  • Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID). It blocks the production of prostaglandins, chemicals that cause inflammation and pain, easing swelling and discomfort in the eye.
  • Moxifloxacin is a fluoroquinolone antibiotic. It blocks bacterial enzymes called DNA gyrase and topoisomerase IV, which bacteria need to replicate their DNA. This stops the bacteria multiplying and clears the infection.
    Together, Ketorolac reduces inflammation while Moxifloxacin treats or prevents bacterial infection in the eye.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 10 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi RoshaMedical Content Writer| 10 years

BAMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ketorolac + Moxifloxacin is available for topical (single-vial sterile ophthalmic solution) use.

Age and Dose Restrictions

  • Ketorolac + Moxifloxacin is meant for adults.

Contraindications

  • Ketorolac + Moxifloxacin is contraindicated for patients with known allergy to either ketorolac, moxifloxacin, or any other NSAIDs or quinolone antibiotics. It should not be used by patients with epithelial herpes simplex keratitis, vaccinia, varicella, mycobacterial and fungal eye infections.

Other Medications to Avoid

  • Ketorolac + Moxifloxacin can interact with anti-coagulants (e.g., warfarin, heparin), SSRIs (e.g., fluoxetine, citalopram), antiplatelet agents (e.g., clopidogrel), Class IA and III antiarrhythmics (e.g., disopyramide, amiodarone), tricyclic antidepressants (e.g., imipramine) and other medicines that prolong the QT interval may have potential interaction with this combination.

Overdose and Missed Dose

  • If you accidentally instil a few extra drops of Ketorolac + Moxifloxacin, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
  • If you miss a dose, instil it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not instil a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For temporary blurred vision after administration, wait until your vision clears before doing any activities.

  • If eye itching, redness, dryness and discomfort occur, try rinsing your eyes with clean water at room temperature.

  • If a headache occurs, rest and relaxation may help. Avoid bright lights and reduce screen time.

Use in Driving and Operating Machinery

  • Ketorolac + Moxifloxacin may cause temporary blurred vision. It is advised to refrain from driving or operating heavy machinery until your vision is clear.

Use in Pregnancy and Lactation

  • Ketorolac + Moxifloxacin should be used with caution during pregnancy, particularly in the third trimester. It is advised to consult your doctor before using this medication combination.

Caution in Other Conditions

  • Patients with a history of recurrent corneal erosion syndrome should use this medication with caution as it may worsen the condition. Patients with known bleeding tendencies or those on anti-coagulants should use this medication cautiously as it may increase bleeding time.

Special Dietary and Lifestyle Recommendations

  • Maintain good hygiene to prevent re-infection or spread of the infection.

  • Avoid touching your eyes with dirty hands.

  • Protect your eyes from dust, smoke, pollen, and other irritants.

  • Rest your eyes frequently if you spend a lot of time reading or in front of screens.

  • Wear sunglasses to protect your eyes from excessive sunlight, which can cause inflammation and discomfort.

Frequently asked questions

Ketorolac + Moxifloxacin is not known to have any effect on sleep. However, if you experience any unusual sleep patterns after using this medicine, you should consult your doctor.

Ketorolac + Moxifloxacin is not known to affect fertility. If you have concerns about fertility, it is advisable to consult your doctor.

It is safe to use Ketorolac + Moxifloxacin as recommended by your doctor. Do not self-medicate or change the dosage without consulting your doctor.

The time taken for Ketorolac + Moxifloxacin to work may vary based on the condition being managed and individual responses. Consult your doctor for detailed information.

The best time to use Ketorolac + Moxifloxacin is as recommended by your doctor. It is usually used at fixed intervals.

Ketorolac + Moxifloxacin does not have any known effect on mood or emotions. However, everyone responds to medication differently, so if you notice changes in your mood, consult your doctor.

Ketorolac + Moxifloxacin does not have any known effects on the menstrual cycle. If you notice changes during your menstrual cycle, consult your doctor.

Terms & Conditions


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