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Ketoconazole + Zinc Pyrithione

Antidandruff

Uses of Ketoconazole + Zinc Pyrithione

Ketoconazole + Zinc Pyrithione is used to treat fungal and yeast-related conditions of the scalp and skin. It combines an antifungal agent with an antimicrobial and antifungal compound for enhanced control of dandruff and related scalp conditions.

This combination is commonly used for:

Dandruff (pityriasis capitis): Reduces the excessive flaking and scaling of the scalp caused by an overgrowth of the yeast Malassezia.

Seborrhoeic dermatitis: Controls the scaly, itchy, inflamed patches on the scalp and hairline associated with this chronic fungal skin condition.

Tinea versicolor (pityriasis versicolor): May be used for this superficial fungal infection that causes discoloured patches on the skin.

Itchy and flaky scalp: Relieves scalp irritation, itching, and visible flaking through its combined antifungal and antimicrobial action.

Side effects of Ketoconazole + Zinc Pyrithione

  • Itching
  • Redness
  • Irritation 
  • Burning sensation 

How Ketoconazole + Zinc Pyrithione works

  • Ketoconazole + Zinc Pyrithione works through two distinct antifungal mechanisms that together provide control of scalp infections.
  • Ketoconazole is an imidazole antifungal agent. It works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane. Without ergosterol, the fungal cell membrane becomes structurally unstable and leaky, leading to fungal cell death. This is particularly effective against Malassezia, the yeast primarily associated with dandruff and seborrhoeic dermatitis.
  • Zinc Pyrithione has antifungal and antibacterial properties. It is thought to act by disrupting membrane transport and cellular processes in fungal cells, leading to growth inhibition.
  • Together, the two agents act through different pathways against fungal organisms, providing broader control of scalp conditions.

Certified content

Written By

docImg
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years

MBBS

Reviewed By

Dr. Mandeep Chadha
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Expert Advice

Dosage Forms Available

  • Ketoconazole + Zinc Pyrithione is available for use via the topical route in the form of shampoo.

Age and Dose Restrictions

  • This medicine is meant for adults.

Contraindications

  • This medicine is contraindicated in patients with known allergies to ketoconazole, other azole derivatives, or zinc pyrithione.

Medications to Avoid with This Drug

  • Inform your doctor if you are using any other medications including over-the-counter medicines that may interact with this medication. 

Overdose and Missed Dose

  • As this is a topical (external use) preparation, the risk of overdose from normal use is very low. If the product is accidentally swallowed, seek immediate medical attention.
  • If you forget to use this medicine as scheduled, apply or use it as soon as you remember. Avoid applying more than the recommended amount to make up for a missed application. Follow the instructions on your prescription regarding frequency of use.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use in Driving And Operating Machinery

  • This medication does not impair your ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • Use this medicine during pregnancy and breastfeeding only if prescribed by your doctor.

Caution in Other Conditions

  • No special precautions need to be taken for patients with other conditions.

Special Dietary & Lifestyle Recommendation

  • To combat inflammation, swelling, and redness, incorporate anti-inflammatory foods into your diet, such as tomatoes, olive oil, green leafy vegetables, strawberries, cherries, blueberries, bell peppers, sweet potatoes, almonds, avocados, and wheat germ.
  • Consider taking fish oil supplements, as they can help suppress flare-ups of dermatitis caused by allergies and boost overall immunity.
  • For skincare, regularly wash affected areas with a mild shampoo and use conditioners, shampoos, and other products containing tea tree oil to relieve itching.
  • During flare-ups, avoid using styling hair sprays and gels, as well as alcohol-based products, which can trigger a reaction.

Frequently asked questions

This medicine's onset of action may require a few weeks for full efficacy to be realised.

If you're allergic to this medicine, don't take it. Seek medical help right away if you have any allergic reactions. 

Please do not discontinue Ketoconazole + Zinc Pyrithione without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.

No special precautions need to be taken for patients with liver or kidney issues.. 

This medication does not affect your fertility, however, discuss it with your doctor before taking it.

Ketoconazole + Zinc Pyrithione is used to treat dandruff, seborrheic dermatitis, and fungal scalp infections. It helps control fungal growth, reduces itching and flaking, and keeps the scalp clean and healthy.

Terms & Conditions


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CIN: U62099MH2019PTC320566
Telephone:09240250346

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Name: Kishor Kumar

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