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Indapamide + Perindopril

Uses of Indapamide + Perindopril

Indapamide + Perindopril is used to manage high blood pressure (hypertension). Indapamide is a diuretic that helps remove excess salt and water from the body, and Perindopril is an ACE inhibitor that helps blood vessels relax and widen.

This combination is commonly used for:

• Hypertension: Lowers high blood pressure when a single medicine does not provide adequate control.
• Long-term blood pressure management: Used as an ongoing treatment to help keep blood pressure within a healthy range.
• Reducing cardiovascular risk in people with stable coronary artery disease: Helps lower the risk of heart attack and cardiovascular death in people with stable coronary artery disease.
• Prevention of stroke: Helps reduce the risk of stroke linked to persistently high blood pressure.

Side effects of Indapamide + Perindopril

  • Cough

  • Dizziness or lightheadedness

  • Headache

  • Fatigue

  • Nausea

How Indapamide + Perindopril works

Indapamide + Perindopril works through two separate actions that together help lower blood pressure.

Indapamide is a thiazide-like diuretic. It works on the kidneys, helping the body remove excess salt and water through urine. This reduces the volume of fluid in the blood vessels, which helps lower blood pressure.

Perindopril is an ACE inhibitor. It works by blocking an enzyme called angiotensin-converting enzyme, which the body uses to produce a hormone called angiotensin II that narrows blood vessels. By blocking this enzyme, Perindopril allows blood vessels to relax and widen.

Together, Indapamide reduces fluid volume while Perindopril widens blood vessels, providing more effective blood pressure control than either medicine alone.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 10 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi RoshaMedical Content Writer| 10 years

BAMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Indapamide + Perindopril is available in tablet form for oral administration.

Age and Dose Restrictions

  • This medicine is meant for adults.

Contraindications

  • This medicine should not be taken by patients with known allergies to indapamide or perindopril.

  • It is also contraindicated in patients with bilateral renal artery stenosis (narrowing of the arteries to both kidneys).

Other Medications to Avoid

  • Indapamide + Perindopril may interact with other diuretics (eg., furosemide or hydrochlorothiazide), NSAIDs (eg., ibuprofen, naproxen) and direct renin inhibitors (eg., aliskiren, remikiren).

Overdose and Missed Dose

  • Taking more than the prescribed dose of Indapamide + Perindopril may cause symptoms such as very low blood pressure, dizziness, dehydration, or fainting. Severe overdose may also cause electrolyte disturbances, kidney impairment, or reduced consciousness. If you suspect an overdose, seek medical attention immediately.
  • If you miss a dose of Indapamide + Perindopril, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For dizziness or lightheadedness, try getting up slowly when rising from a sitting or lying position.

  • Increased thirst can be managed by drinking enough fluids unless instructed otherwise by your doctor.

Use in Driving and Operating Machinery

  • Indapamide + Perindopril may cause dizziness, therefore, it may affect your ability to drive or operate machinery. Avoid these activities if you feel dizzy after taking this medicine.

Use in Pregnancy and Lactation

  • Indapamide + Perindopril is not recommended during pregnancy or while breastfeeding. Consult your doctor before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Caution in Other Conditions

  • Patients with kidney disease, liver disease, diabetes or heart disease should exercise caution when taking Indapamide + Perindopril.

Special Dietary and Lifestyle Recommendations

  • Regular monitoring of blood pressure is crucial for patients taking this medication.

  • Regular physical activity, like walking or swimming, can also help lower blood pressure.

Frequently asked questions

No, the medicine combination of Indapamide + Perindopril is not a steroid. It is primarily used for managing high blood pressure and is made up of an angiotensin-converting enzyme (ACE) inhibitor (Perindopril) and a diuretic (Indapamide).

Indapamide + Perindopril is not associated with any direct effects on sleep. These medications are used to manage high blood pressure and do not typically impact sleep patterns.

Indapamide + Perindopril is not associated with any effects on fertility. They are primarily used for managing high blood pressure, with no known impact on fertility.

Yes, it is safe to take Indapamide + Perindopril daily as recommended by your doctor. It is used to manage high blood pressure and should be taken for the duration prescribed by your doctor.

The time for the medication to show its effects may vary for each individual based on their body's response to the medication. You should consult your doctor for specifics related to your treatment.

The best time to take Indapamide + Perindopril is as prescribed by your doctor. It is generally recommended to be taken at the same time each day for the best results.

No, you cannot buy Indapamide + Perindopril over the counter. This medication usually requires a prescription from a doctor.

Terms & Conditions


List of medicines for Indapamide + Perindopril

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Coversyl Plus Hd Tablet 10
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Perindprim Plus Tablet 10
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Pack of 10 Units
₹79.22
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Perigard D Tablet 10
Perigard D Tablet 10
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Pack of 10 Units
₹89.33
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Conape Plus 4/1.25 Mg Tablet 10
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Eviper D 4/1.25 Mg Tablet 10
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₹81.75
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Perigard-Df 2/1.2 Mg Tablet 10
Perigard-Df 2/1.2 Mg Tablet 10
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Coversyl Plus Tablet 10
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