Iguratimod is a disease-modifying antirheumatic drug (DMARD) used to manage rheumatoid arthritis, an autoimmune condition that causes joint pain and swelling.
Iguratimod is commonly used for:
• Rheumatoid arthritis: Reduces joint pain, swelling, and stiffness by controlling the underlying immune-related inflammation.
• Slowing joint damage: Helps limit long-term joint damage caused by ongoing inflammation in rheumatoid arthritis.
• Combination therapy: Often used alongside other DMARDs, such as methotrexate, when a single medicine does not adequately control symptoms.
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Iguratimod works by reducing the production of inflammatory substances in the body that drive joint damage in rheumatoid arthritis.
In rheumatoid arthritis, the immune system mistakenly attacks the lining of the joints, causing inflammation. This process is driven by chemical messengers called cytokines, which trigger swelling, pain, and gradual damage to joint tissue.
Iguratimod is thought to suppress the production of these inflammatory cytokines and reduce the activity of immune cells involved in joint inflammation. By controlling this underlying immune response, Iguratimod helps reduce joint pain and swelling and slows the progression of joint damage over time.

Doctor of Medicine

BAMS, FMC, MD Resident
Iguratimod is available as an oral medication in the form of tablets. It is indicated for use via the oral route.
This medicine is meant for adults only.
Individuals with severe liver impairment should not use Iguratimod.
It is also contraindicated in individuals with severe renal impairment, and severe or uncontrolled infections.
Iguratimod can interact with anticoagulants (such as warfarin), immunosuppressants (such as cyclosporine) and potentially hepatotoxic medications (like acetaminophen).
If you miss a dose of Iguratimod, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the one you missed.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For managing gastrointestinal effects like nausea and diarrhoea, try taking the medication with food.
Staying well-hydrated may help alleviate symptoms like constipation or dizziness.
Iguratimod may cause dizziness or fatigue. It is recommended to avoid driving or operating heavy machinery if such side effects are experienced.
The safety of Iguratimod during pregnancy and lactation has not been established. Hence, it is advised to consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution is advised for patients with pre-existing liver disease, kidney impairment, individuals at an increased risk of infection, and elderly patients while using Iguratimod.
Regular monitoring of liver function tests should be done when using this medicine.
Eating a balanced diet rich in fruits, vegetables, lean proteins and whole grains can help manage the underlying condition - rheumatoid arthritis.
Engaging in low-impact exercises such as walking, cycling or swimming can help maintain joint flexibility and build muscle strength.
Frequently asked questions
Iguratimod is not associated with causing sleep disturbances. It is primarily used for managing rheumatoid arthritis and does not typically impact sleep patterns.
Iguratimod is not associated with any impact on fertility. It is used for managing rheumatoid arthritis and has no known effects on reproductive health.
Yes, but it should only be taken as per the duration and dosage advised by your doctor.
The onset of action of Iguratimod can vary from person to person; however, some improvement in symptoms may be noticed within 4 weeks.
Yes, a prescription from a registered medical practitioner is required to obtain Iguratimod.
No, Iguratimod is not a steroid. It is a disease-modifying antirheumatic medicine (DMARD) that is primarily utilized to manage rheumatoid arthritis.
Before starting Iguratimod treatment, patients need to undergo a complete blood count, liver function tests, and kidney function tests. These tests need to be repeated regularly during treatment to check for side effects.
Iguratimod is used to manage rheumatoid arthritis. It helps reduce joint inflammation, pain, and stiffness by modulating the immune response and slowing disease progression.








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