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Dicyclomine + Nimesulide

Uses of Dicyclomine + Nimesulide

  • Dicyclomine + Nimesulide is primarily used to manage painful gastrointestinal spasms and cramps associated with conditions like irritable bowel syndrome (IBS) and belongs to the group of anticholinergic and nonsteroidal anti-inflammatory medicines.

  • It is also indicated for painful menstruation (dysmenorrhea), intestinal colic, biliary colic and spasms, and as adjunctive treatment of peptic ulcer.

Side effects of Dicyclomine + Nimesulide

  • Dry mouth, throat, and nose

  • Blurred vision

  • Drowsiness or dizziness

  • Nausea or vomiting

  • Constipation

How Dicyclomine + Nimesulide works

  • Dicyclomine + Nimesulide is a combination medication with antispasmodic and anti-inflammatory properties.

  • Dicyclomine is an anticholinergic agent. It functions by blocking the action of a neurotransmitter called acetylcholine in areas like smooth muscle and secretory glands. This results in relaxation of smooth muscles, particularly in the digestive system, thus helping to ease spasms and cramps.

  • Nimesulide is a Nonsteroidal Anti-inflammatory Drug (NSAID), specifically selective COX-2 inhibitor. Through inhibiting the COX-2 enzyme, it hinders the production of prostaglandins, substances contributing to inflammation and pain. This leads to its anti-inflammatory, analgesic and fever-reducing effects.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Dicyclomine + Nimesulide is available in the form of tablets for use via the oral route.

Age and Dose Restrictions

  • This medicine is meant for adults and children above the age of 12 years.

Contraindications

  • Dicyclomine + Nimesulide is contraindicated in patients with known hypersensitivity to either dicyclomine, nimesulide or any excipients.

  • It is also contraindicated in patients with severe hepatic, renal or cardiac impairment and during or just before coronary artery bypass graft surgery.

Other Medications to Avoid

  • This combination may interact with anticholinergic medicines (such as atropine and scopolamine), tricyclic antidepressants (such as amitriptyline and imipramine), anticoagulants (like warfarin and heparin), SSRIs (like fluoxetine and sertraline) and other NSAIDs (such as aspirin and ibuprofen).

Overdose and Missed Dose

  • An overdose of this medication may cause symptoms such as excessive dryness of mouth, blurring of vision, nausea, vomiting, weakness, drowsiness or dizziness. If you experience any of these symptoms, inform your doctor immediately.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dry mouth, drink plenty of water throughout the day.

  • Rest and avoid performing physical activities if you feel dizzy or weak.

  • If you experience nausea, try taking the medicine with food or milk.

Use in Driving and Operating Machinery

  • Dicyclomine + Nimesulide may cause drowsiness or dizziness. These effects may affect your ability to drive or operate machinery. Avoid these activities if you feel affected after taking this medicine.

Use in Pregnancy and Lactation

  • Use of Dicyclomine + Nimesulide is contraindicated during pregnancy and lactation. If you are pregnant or breastfeeding, consult your doctor before using this medicine.

Caution in Other Conditions

  • Dicyclomine + Nimesulide should be used with caution in patients with glaucoma, obstructive diseases of the gastrointestinal or urinary tract, myasthenia gravis, hypertension, congestive heart failure, and in patients with bleeding disorders.

Special Dietary and Lifestyle Recommendations

  • Maintain a diet rich in fibre to help regulate bowel movements and reduce the chance of constipation.

  • Stay well hydrated by drinking plenty of water throughout the day.

  • Regular low-intensity physical activity such as walking can help manage symptoms associated with irritable bowel syndrome (IBS).

  • Limit intake of caffeinated drinks as they can worsen the symptoms of IBS.

  • Try relaxation techniques such as deep breathing exercises and yoga to help reduce stress and anxiety which can trigger IBS symptoms.

Frequently asked questions

No, Dicyclomine + Nimesulide is not a steroid. It is a combination of an anticholinergic and a nonsteroidal anti-inflammatory medication.

Dicyclomine + Nimesulide does not usually cause mood changes. However, if you notice any significant changes in your mood or behaviour while taking this medicine, inform your doctor.

There are no known contraindications for people with diabetes taking Dicyclomine + Nimesulide. However, it is always best to discuss any existing conditions with your doctor before starting a new medication.

Check the packaging or patient information leaflet to see if Dicyclomine + Nimesulide contains gluten. If you have coeliac disease or a sensitivity to gluten, always consult your doctor before starting new medications.

Yes, the active ingredients in Dicyclomine + Nimesulide are synthetic and do not come from animal sources. However, some tablet coatings may contain ingredients derived from animals. If you follow a vegetarian or vegan diet, check with your pharmacist to make sure the specific brand you are prescribed is suitable for your dietary needs.

There are no known effects of Dicyclomine + Nimesulide on menstruation. However, it is used to manage painful menstruation (dysmenorrhea).

The onset of action can vary depending on individual response and the specific condition being managed. Your doctor will be able to provide you with more personalized information.

Terms & Conditions


Available medicines for DICYCLOMINE + NIMESULIDE
Antica 20/100 MG Drops 10 ML
Antica 20/100 MG Drops 10 ML
Rhombus Pharma
Pack of 10 ML
₹31.98
MRP ₹39.00
18.00% OFF
Nise Spas 10/50 MG Tablet 10
Nise Spas 10/50 MG Tablet 10
Dr. Reddys Laboratories Ltd
Pack of 10 Units
₹22.21
MRP ₹27.08
18.00% OFF
Nicispas 20/100 MG Tablet 10
Nicispas 20/100 MG Tablet 10
Cipla Ltd.
Pack of 10 Units
₹19.96
MRP ₹40.00
50.10% OFF
Arsulide D 10/100 MG Tablet 10
Arsulide D 10/100 MG Tablet 10
Sterkem
Pack of 10 Units
₹57.40
MRP ₹70.00
18.00% OFF
Dolospan 20/10 MG Tablet 10
Dolospan 20/10 MG Tablet 10
Emcure Pharmaceuticals Ltd
Pack of 10 Units
₹59.04
MRP ₹72.00
18.00% OFF
Dyspas N 20/100 MG Tablet 10
Dyspas N 20/100 MG Tablet 10
Embiotic Lab
Pack of 10 Units
₹18.66
MRP ₹22.75
18.00% OFF
Antica 20/100 MG Tablet 10
Antica 20/100 MG Tablet 10
Rhombus Pharma
Pack of 10 Units
₹20.50
MRP ₹25.00
18.00% OFF
Termispaz 10/100 MG Tablet 10
Termispaz 10/100 MG Tablet 10
Resilient Cosmeceuticals Private Limited
Pack of 10 Units
₹56.58
MRP ₹69.00
18.00% OFF

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